Assuntos
Anestesiologistas/estatística & dados numéricos , Deficiência de Vitamina D/epidemiologia , Vitamina D/análogos & derivados , Adulto , Chile/epidemiologia , Feminino , Humanos , Hiperparatireoidismo/epidemiologia , Hiperparatireoidismo/etiologia , Internato e Residência , Masculino , Pessoa de Meia-Idade , Prevalência , Estações do Ano , Luz Solar , Inquéritos e QuestionáriosRESUMO
Four hundred and eighty six infected adults (90,7 percent men) were prospectively followed from 1988 to 1993 at a multi-professional center in Santiago, Chile. 87,8 percent of male patients (pts), 84 percent of them homo/bisexual, and 64,4 percent of women acquired the infection sexually. At the beginning of the follow up (F/U) 51 percent of men and 71 percent of women were asymptomatic and 30 percent of the total group had AIDS. (AIDS definition: CDC 1993, excluded CD4 lymphocyte count <200 x mm3). 240/486 (49,4 percent) had developed AIDS at the end of the study (12/31/93). AIDS defining events (ADE) were: interstitial pneumonia (confirmed or suggestive as caused by P. carinii [PCP]), 25 percent; tuberculosis (all forms), 22.1 percent; wasting, 13.8 percent; Kaposi Sarcoma, 9.2 percent; esophageal candidiasis, 6.7 percent; isosporiasis, 5,4 percent. Of all PCP cases, 72 percent were ADE, the rest, post AIDS'. As expected, AIDS pts continued having major complications (mainly bacterial pneumonias, PCPs, esophagitis, tuberculosis and diarrhea due to I. belli and Cryptosporidium. Less frequently, but also observed, were toxoplasmic encephalitis and cryptococcal meningitis). Known mortality (excluded abandonment of F/U) was 27 percent for the whole group and varied from 5.8 percent, 51,6 percent to 69.2 percent for the first, 4th and 6th yaer of F/U respectively. For II-III CDC pts the mortality was 5 percent and 57 percent and for IV CDC pts it was 38 percent and 100 percent during the first and 6th year of F/U respectively. 36 percent, 53 percent, 74 percent and 85 percent of the pts followed for 1, 3, 5 and 6 years respectively had developed AIDS by the end of 1993. Multifactorial causes with either diarrhea, wasting or both were responsible for the death in half the pts in whom this was known, 15 percent died of respiratory complications and 5,7 percent of cryptococcal meningitis. 80 percent of AIDS pts survived their ADE. This study has provided information about the clinical profile of the HIV infection and natural history of the disease in Chile
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Infecções por HIV/diagnóstico , Síndrome da Imunodeficiência Adquirida/diagnóstico , Homossexualidade/estatística & dados numéricos , Infecções por HIV/transmissão , Infecções por HIV/epidemiologia , História Natural das Doenças , Intervalo Livre de Doença , Distribuição por Sexo , Síndrome da Imunodeficiência Adquirida/epidemiologia , Síndrome da Imunodeficiência Adquirida/transmissãoRESUMO
Se realizó un estudio en 277 pacientes con cuadro dispéptico lográndose un diagnóstico causal mediante endoscopia o radiología de las vías digestivas altas, siendo la gastritis y la hernia hiatal con reflujo los diagnósticos más frecuentes. Todos los pacientes fueron tratados con una asociación de Bromopride, un enzimatico y DMP, permitiéndose una medicación concomitante en algunos casos. El 95.3 por ciento de los pacientes al final del estudio reportaron ausencia de los síntomas estudiados; y el 98.2 por ciento tuvieron una respuesta terapéutica considerada entre buena y muy buena. Los pacientes tratados con medicaciones concomitantes (anti-H2 o antiácidos) tuvieron tasas de mejoría similares o mejores que no fueron estadísticamente significativas con el resto del grupo. Se concluyó en este trabajo que la medicación propuesta, es efectiva para el tratamiento de estos cuadros y que es necesario para el médico y beneficioso para el paciente identificar la causa de dispepsia