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Background: Most residents do not have a defined program for simulation training in video surgery in Brazil. The training takes place for the most part in vivo or in short courses. The goal of this article is to describe and evaluate a set of exercises using low-cost materials, created by the residents themselves, to enable basic skills training in video surgery. Materials and Methods: Seven exercises were elaborated aiming to simulate main maneuvers performed in video surgery. The residents were guided by a written and video description showing the execution of the exercises, performed the exercises, and answered a questionnaire. After 3 weeks of free training, the residents performed the exercises and answered the questionnaire again. Results: Seven residents started the study; however, 6 completed the two steps. Among the participants, 83% received in vivo video surgery training, and only 2 (33%) received some supervised simulation training in minimally invasive surgery before this time. All participants considered the set of seven exercises representative of the actual skills in video surgery. There was no difficulty in acquiring the materials or in assembling them to carry out the training. All the participants had a shorter training time than initially proposed, on average 1 day/week for 20 minutes. Conclusions: A simple set of exercises can be elaborated by the residents themselves and make feasible the simulated training in video surgery even without the availability of sophisticated and expensive materials. The presence of a tutor and the scheduling of exclusive training seem necessary for more satisfactory results.

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Objective To evaluate post-operative complications of circumcision requiring surgical reintervention. Methods Retrospective analysis of medical records of patients submitted to circumcision from May 1st, 2015 to May 31st, 2016. Results A total of 2,441 circumcisions were performed; in that, 1,940 using Plastibell and 501 by the classic technique. Complications requiring surgical reintervention were found in 3.27% of patients. When separated by surgical technique, 3.4% of circumcisions using Plastibell device required reoperation, as compared to 3% of conventional technique (p=0.79). Preputial stenosis was most frequently found in classic circumcision, with statistical significance (p<0.001). Bleeding was more frequent when using Plastibell device, but the difference was not statistically different (p=0.37). Patients' age was also evaluated to investigate if this variable influenced on the postoperative outcome, but no significant difference was found. Conclusion There was no statistically significant difference when comparing complications between the different techniques performed at this hospital. Preputial stenosis was most frequently found in the classic circumcision, while bleeding was more prevalent when using Plastibell device. Patients' age did not influence in complications.

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ABSTRACT Objective To evaluate post-operative complications of circumcision requiring surgical reintervention. Methods Retrospective analysis of medical records of patients submitted to circumcision from May 1st, 2015 to May 31st, 2016. Results A total of 2,441 circumcisions were performed; in that, 1,940 using Plastibell and 501 by the classic technique. Complications requiring surgical reintervention were found in 3.27% of patients. When separated by surgical technique, 3.4% of circumcisions using Plastibell device required reoperation, as compared to 3% of conventional technique (p=0.79). Preputial stenosis was most frequently found in classic circumcision, with statistical significance (p<0.001). Bleeding was more frequent when using Plastibell device, but the difference was not statistically different (p=0.37). Patients' age was also evaluated to investigate if this variable influenced on the postoperative outcome, but no significant difference was found. Conclusion There was no statistically significant difference when comparing complications between the different techniques performed at this hospital. Preputial stenosis was most frequently found in the classic circumcision, while bleeding was more prevalent when using Plastibell device. Patients' age did not influence in complications.

RESUMO Objetivo Avaliar as complicações pós-operatórias de postectomia que necessitaram de reintervenção cirúrgica. Métodos Estudo retrospectivo com análise de prontuários de pacientes submetidos à postectomia entre 1o de maio de 2015 a 31 de Maio de 2016. Resultados Foram realizadas 2.441 postectomias no período, sendo 501 utilizando a técnica clássica e 1.940 utilizando o dispositivo Plastibell. Apresentaram complicações que necessitaram reintervenção cirúrgica 3,27% dos pacientes. Quando separados por técnica operatória, 3,4% das postectomias com Plastibell foram reoperadas, comparando com 3% das postectomias convencionais (p=0,79). A estenose de prepúcio foi mais frequentemente encontrada na técnica clássica, com significância estatística (p<0,001). Sangramento foi mais frequente nos casos com uso do Plastibell, porém sem diferença significativa (p=0,37). A idade dos pacientes também foi avaliada para investigar se esta variável influenciou na taxa de complicações pós-operatórias, porém não houve diferença significativa. Conclusão Não houve diferença estatisticamente significativa quando comparadas as complicações entre as diferentes técnicas cirúrgicas utilizadas neste serviço. A estenose de prepúcio foi mais frequentemente encontrada nos pacientes operados pela técnica convencional enquanto demonstrou-se tendência a maior sangramento com uso do Plastibell. A idade dos pacientes não influenciou na presença de complicações.

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Objetivos: Analisar dados epidemiológicos de pacientes submetidos à PAAF, classificados como lesões foliculares (classe IV) e suspeitos para malignidade (classe V) pelo Sistema Bethesda para Laudos Citopatológicos da Tireoide e avaliar o desempenho do painel imunocitoquímico com os marcadores CK-19, Galectina-3 e HBME-1 no diagnóstico destes pacientes. Metodologia: Estudo retrospectivo transversal, que analisou 24 laudos anatomopatológicos do Centro de Patologia de Curitiba, entre 2011 e 2014, classificados como classe IV e V do Sistema Bethesda, cujas lâminas foram avaliadas pela imunocitoquímica, usando-se os marcadores CK-19, GAL-3 e HBME-1. Resultados: 83,3% dos pacientes eram mulheres, com idade média de 45,7 anos. O tamanho médio das lesões foi 12,5mm, localizadas 56,5% no lobo D. O painel de marcadores apresentou sensibilidade 100%, especificidade 90,5% e eficácia 95,5% para as lesões avaliadas. Conclusão: A imunocitoquímica demostrou-se um exame pré-operatório eficaz para diferenciação de lesões foliculares e suspeitas para malignidade do carcinoma papilífero da tireoide

Objectives: To analyze epidemiological data of patients who undergone FNA that was classified as follicular lesions (Class IV) and suspicious for malignancy (Class V) by the Bethesda System for Reporting Thyroid Cytopathology and evaluate the performance of immunocytochemical panel with markers CK-19, Galectin-3 and HBME-1 in these patients. Methodology: This is a cross-sectional retrospective study. It was analyzed 24 pathological between 2011 and 2014, from the Curitiba Pathology Center, classified as Class IV and V in the Bethesda System for Reporting Thyroid Cytopathology, which slides were stained with immunocytochemistry using the markers: CK19 GAL-13 and HBME-1. Results: In this study 83.3% of the patients were women with a mean age of 45.7 years. The average size of the nodules was 12.5mm and 56.5% was located in the right lobe. Regarding the diagnosis of follicular lesions and suspicious for malignancy, the sensitivity of the exam with the standard biological markers used was 100%, specificity 90,5% and efficacy 95.5%. Conclusion: The immunocytochemistry demonstrated to be an effective pre-operative exam for differentiation of follicular lesions and suspicious for malignancy of papillary thyroid carcinoma

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Objetivos: Analisar dados epidemiológicos de pacientes submetidos à PAAF, classificados como lesões foliculares (classe IV) e suspeitos para malignidade (classe V) pelo Sistema Bethesda para Laudos Citopatológicos da Tireoide e avaliar o desempenho do painel imunocitoquímico com os marcadores CK-19, Galectina-3 e HBME-1 no diagnóstico destes pacientes. Metodologia: Estudo retrospectivo transversal, que analisou 24 laudos anatomopatológicos do Centro de Patologia de Curitiba, entre 2011 e 2014, classificados como classe IV e V do Sistema Bethesda, cujas lâminas foram avaliadas pela imunocitoquímica, usando-se os marcadores CK-19, GAL-3 e HBME-1. Resultados: 83,3% dos pacientes eram mulheres, com idade média de 45,7 anos. O tamanho médio das lesões foi 12,5mm, localizadas 56,5% no lobo D. O painel de marcadores apresentou sensibilidade 100%, especificidade 90,5% e eficácia 95,5% para as lesões avaliadas. Conclusão: A imunocitoquímica demostrou-se um exame pré-operatório eficaz para diferenciação de lesões foliculares e suspeitas para malignidade do carcinoma papilífero da tireoide

Objectives: To analyze epidemiological data of patients who undergone FNA that was classified as follicular lesions (Class IV) and suspicious for malignancy (Class V) by the Bethesda System for Reporting Thyroid Cytopathology and evaluate the performance of immunocytochemical panel with markers CK-19, Galectin-3 and HBME-1 in these patients. Methodology: This is a cross-sectional retrospective study. It was analyzed 24 pathological between 2011 and 2014, from the Curitiba Pathology Center, classified as Class IV and V in the Bethesda System for Reporting Thyroid Cytopathology, which slides were stained with immunocytochemistry using the markers: CK19 GAL-13 and HBME-1. Results: In this study 83.3% of the patients were women with a mean age of 45.7 years. The average size of the nodules was 12.5mm and 56.5% was located in the right lobe. Regarding the diagnosis of follicular lesions and suspicious for malignancy, the sensitivity of the exam with the standard biological markers used was 100%, specificity 90,5% and efficacy 95.5%. Conclusion: The immunocytochemistry demonstrated to be an effective pre-operative exam for differentiation of follicular lesions and suspicious for malignancy of papillary thyroid carcinoma

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Objetivo: Avaliar a relação entre a massa óssea e marcadores séricos de estresse oxidativo/ antioxidação (bilirrubina total/frações e ácido úrico), bem como averiguar a associação entre tais variáveis e outros dados que interferem na massa óssea (idade, alcoolismo, tabagismo, raça, tempo de menopausa e histórico de fraturas). Dosagem de aminotransferases e de enzimas canaliculares foram usadas como marcadores de integridade hepática. Método: Foram selecionados 105 pacientes.A análise do índice de massa óssea foi feita pela verificação dos escores Z, T e g/cm2 (BMD) em fêmur total e coluna vertebral lombar por densitometria pelo método DEXA.Resultados: Foram encontradas correlações entre bilirrubina direta e: T-score (p = 0,0004) e BMD (p=0,0177) de coluna lombar. Também houve correlação entre a bilirrubina total e o T-score de quadril (p= ,0239). Os estudos de correlação entre massa óssea e bilirrubina indireta e com acido úrico não obtiveram resultado significante (p=ns).Conclusão: Existe associação entre bilirrubina total e bilirrubina direta com massa óssea, mostrando que o prejuízo de massa óssea está associado com consumo destes marcadores.

Objective: To evaluate the relation between bone mass and serum markers of oxidative stress/oxidation (total bilirubin / fractions and uric acid), and investigate the association between these variables and other data that interfere with bone (age, alcoholism, smoking, race, time since menopause and history of fractures). aminotransferase dosage and GGT were used as liver integrity markers.Method: About 105 patients were selected. Analysis of bone mass index was made by checking the Z scores, and T g / cm2 (BMD) in total hip and lumbar spine by densitometry by DEXA method.Results: Correlations were found between and direct bilirubin: T-score (p = 0.0004) and BMD (p = 0.0177) in the lumbar spine. There was also a correlation between total bilirubin and hip T-score (p = 0239). The correlation studies between bone mass and indirect bilirubin and uric acid did not obtain significant result (p = ns).Conclusion: There is an association between total bilirubin and direct bilirubin with bone mass, showing that the loss of bone mass is associated with consumption of these markers.

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Objetivo: Verificar a frequência de instabilidade de microssatélites (IMS) em casos de carcinoma colorretal, bem como seus fatores de risco. Material e Método: Foram analisados históricos de pacientes com CCR, avaliando sexo, idade, presença ou ausência de instabilidade de microssatélites MLH-1 e MSH- 2, positividade e negatividade do marcador p53, reatividade do marcador Ki67, profundidade da lesão, invasão vascular e linfonodal e localização do tumor. Resultados: Obteve-se 10,37% de casos com IMS. Não houve correlação entre IMS e idade, gênero, localização do tumor, invasão linfonodal e vascular, profundidade da lesão, mutação de TP53 e taxa de proliferação por anti Ki67. Conclusão: Nesse estudo a presença de IMS no CCR não apresentou relação com fatores clínicos e epidemiológicos conhecidos para essa neoplasia.

Objective: The aim of this study was to verify the frequency of microsatellite instability (MSI) in cases of colorectal carcinoma and their risk factors. Material and Method: We analyzed historical CRC patients, evaluating sex, age, instability MLH -1 microsatellite and MSH- 2 , positivity of the p53 marker, percentage of Ki67 marker , presence of lymph nodes metastases , depth of lesion , vascular and lymph nodes invasion and tumor location. Results: There was 10.37 % of cases with IMS. There was no correlation between IMS and age, gender, tumor location , lymph node and vascular invasion, depth of the lesion , TP53 mutation and proliferation rate by anti Ki67. Conclusion: The presence of IMS in CRC is not related with clinical and epidemiological factors known to this neoplasm.

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Portadores de fibromialgia queixam-se de dor generalizada, fadiga e distúrbios do sono. Os exames laboratoriais são caracteristicamente negativos nesta patologia. Devido à natureza pouco específica dos sintomas e a falta de provas palpáveis de um processo inflamatório, estes pacientes nem sempre têm as suas queixas devidamente valorizadas. No presente estudo procurou-se demonstrar o grande impacto desta patologia na qualidade de vida de seus portadores comparando-a com a de portadores de artrite reumatóide. Além disso procurou-se verificar se este prejuízo estava associado com o grau de dor percebido pelo paciente ou com o número de pontos sensíveis encontrados ao exame físico.

Fibromyalgia patients complain of generalized pain, fatigue and sleep disturbance. Laboratory exams are typically negative in this pathology. Due to this lack of symptom's specificity and palpable proofs of inflammatory disease, these patients complaints are not taken seriously. In this study we try to demonstrate the high impact of fibromyalgia in the patient's life quality comparing them with rheumatoid arthritis patients. We also try to verify the relationship between poor life quality with generalized pain and number of tender points at physical examination.