RESUMO
A clinical case of placental site trophoblastic tumor, is presented in a patient of 27 years old. Diagnosis, clinical behavior and treatment are emphasized in this very infrequent pathology.
Assuntos
Tumor Trofoblástico de Localização Placentária/patologia , Neoplasias Uterinas/patologia , Adulto , Feminino , Seguimentos , Humanos , GravidezAssuntos
Adenocarcinoma/cirurgia , Laparoscopia , Neoplasias Ovarianas/cirurgia , Idoso , Feminino , Humanos , ReoperaçãoRESUMO
Three extracorporal uterine endometrial stromal-like sarcomas are reported. One of them was a bilateral ovarian sarcoma, with extensive infiltration and vascular compromise of paratubarian tissues, parametrium, omentum, and periureteral tissue. Endometriotic foci were also found in the ovaries and periureteral tissue. The other two cases corresponded to localized polypoid lesions of the endocervical and vaginal mucosa, respectively. None of these cases was associated with endometriosis. Histologically, the tumors were made up of rounded cells, with scant cytoplasm, numerous small vessels and low mitotic index. The findings correspond to those of low grade endometrial stromal sarcomas. The present cases emphasize the multipotentiality of müllerian organs. Not only different types of paramesonephric epithelial tumors can develop from these organs, but also different müllerian sarcomas.
Assuntos
Neoplasias dos Genitais Femininos/patologia , Sarcoma do Estroma Endometrial/patologia , Adulto , Feminino , Humanos , Neoplasias Ovarianas/patologia , Neoplasias do Colo do Útero/patologia , Neoplasias Vaginais/patologiaRESUMO
A uterine smooth muscle tumor belonging to the category of unknown malignant potential in a 20-year-old woman is reported. The major axis of the tumor was 5 cm, and the tumor was soft and homogeneous. Histologically, it was composed of cellular groups, arranged in an epithelioid pattern, with hyaline bands dissecting the groups, moderate nuclear hyperchromasia and pleomorphism, and mitotic index of 2 per 10 high power fields; the tumor had infiltrating margins and tumoral vascular invasions were found. Immunohistochemically, the tumor was positive for vimentin, and negative for keratins, desmin, actin, and S 100 protein. Epithelioid smooth muscle tumors of the uterus should be classified as tumors of unknown malignant potential under the following conditions: if they are larger than 5 cm, if they show at least moderate cellular pleomorphism, if their mitotic index is at least 1 per 10 high power fields, or if they show cellular necrosis. The present immunohistochemical findings suggest more a fibroblastic than a smooth muscle cell origin of this neoplasm.
Assuntos
Leiomioma Epitelioide/patologia , Neoplasias Uterinas/patologia , Adulto , Feminino , HumanosRESUMO
Between 1987 to 1992, nine patients with metastatic ovarian tumors of extragenital origin were analyzed. Seven corresponded to Krükenberg tumors, according to the traditional description of carcinoma with signet-ring cells and stroma with sarcomatoid reaction. The primary neoplasia was detected in 8 patients (89%) and corresponded to: gastric cancer (n = 4), colon cancer (n = 2), gallbladder cancer (n = 1) and breast cancer (n = 1). Mean survival in these patients was 11 months (range 4 to 20 months). Irrespective of their histology and origin, all the lesions were found to share similar macroscopic characteristics: bilateral enlarged ovaries, solid and embossed appearance.
Assuntos
Tumor de Krukenberg/secundário , Neoplasias Ovarianas/secundário , Neoplasias Gástricas/patologia , Adulto , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Tumor de Krukenberg/patologia , Pessoa de Meia-Idade , Neoplasias Ovarianas/patologia , Estudos RetrospectivosRESUMO
Three hundred and five patients undergoing exploratory laparotomy by adnexial tumors in our institution from January 1987 to October 1992 were studied. The results of the frozen sections vs permanent sections were compared. The diagnosis was concordant in 98.7% of the cases. Sensitivity was 96.9% and specificity was 99.6%. These results consagrate frozen sections as an accuracy and efficient intraoperative diagnostic form in the ovary tumoral pathology.
Assuntos
Secções Congeladas , Neoplasias Epiteliais e Glandulares/patologia , Neoplasias Ovarianas/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Criança , Feminino , Humanos , Pessoa de Meia-Idade , Sensibilidade e EspecificidadeRESUMO
One observed case of verrucous carcinoma involving the uterine cervix is presented. Both clinical and pathologic aspects, and pertinent literature are discussed.