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Objetivo: Estimar a incidência de eventos adversos e identificar os fatores associados à sua ocorrência em pacientes cirúrgicos de um hospital geral de referência do interior de Minas Gerais, Brasil. Método: Estudo retrospectivo e documental realizado em 851 prontuários de pacientes submetidos a procedimentos cirúrgicos. Para rastrear e identificar o evento adverso, utilizou-se uma adaptação do método Global Trigger Tool, adotou-se a dupla revi-são dos documentos de forma independente e a análise de dados por estatística descritiva, teste χ2, t de Student e regressão logística. Resultados: Foram identificados 145 eventos adversos em 108 prontuários, mais da metade relacionada a complicações no local da cirurgia, como sangramento e infecções de sítio cirúrgico. O tempo de internação prolongado, a duração da cirurgia superior a quatro horas e procedimentos cirúrgicos classificados como con-taminados mostraram-se associados a maiores chances de ocorrência do evento adverso (p<0,001). Conclusão: Os eventos adversos na assistência cirúr-gica possuem elevada frequência e impacto de danos causados, reforçando a importância das estratégias voltadas para a segurança do paciente cirúrgico

Objective: To estimate the incidence of adverse events and identify the factors associated with their occurrence in surgical patients at a general reference hospital in the interior of Minas Gerais, Brazil. Method: Retrospective and documentary study carried out in 851 medical records of patients undergoing surgical procedures. To track and identify the adverse event, an adaptation of the Global Trigger Tool method was used, with double review of documents independently and data analysis using descriptive statistics, χ2 test, Student's t-test and logistic regression. Results: 145 adverse events were identified in 108 medical records, more than half related to complications at the surgical site, such as bleeding and surgical site infections. Prolonged hos-pital stay, duration of surgery longer than four hours and surgical procedures classified as contaminated were associated with greater chances of adverse event occurrence (p<0.001). Conclusion: Adverse events in surgical care have a high frequency and impact of damage caused, reinforcing the importance of strategies aimed at the safety of surgical patients

Objetivo: Estimar la incidencia de eventos adversos e identificar los factores asociados a su ocurrencia en pacientes quirúrgicos en un hospital general de referencia en el interior de Minas Gerais, Brasil. Método: Estudio retrospectivo y documental realizado en 851 historias clínicas de pacientes sometidos a procedimientos quirúrgicos. Para el seguimiento e identificación del evento adverso se utilizó una adaptación del método Global Trigger Tool. Se adoptó el procedimiento de doble revisión de documentos de forma independiente y el análisis de datos se realizó mediante estadística descriptiva, prueba de chi-cuadrado, prueba t de Student y regresión logística. Resultados: Se identificaron 145 eventos adversos en 108 historias clínicas. Más de la mitad se relacionaron con complicaciones en el sitio quirúrgico, como sangrado e infecciones del sitio quirúrgico. La estancia hospitalaria prolongada, la duración de la cirugía mayor a cuatro horas y la realización de procedimientos quirúrgicos clasificados como contaminados se asociaron con mayo-res posibilidades de ocurrencia de eventos adversos (p<0,001). Conclusión: Los eventos adversos en la atención quirúrgica tienen una alta frecuencia e impacto del daño causado, reforzando la importancia de las estrategias dirigidas a la seguridad de los pacientes quirúrgicos

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OBJECTIVE: the study evaluated the effect of using the safe surgery checklist (CL) on the incidence of adverse events (AE). METHODS: cross-sectional and retrospective research with 851 patients undergoing surgical procedures in 2012 (n=428) and 2015 (n=423), representing the periods before and after CL implantation. The AE incidences for each year were estimated and compared. The association between the occurrence of AE and the presence of CL in the medical record was analyzed. RESULTS: a reduction in the point estimate of AE was observed from 13.6% (before using the CL) to 11.8% (with the use of the CL). The difference between the proportions of AE in the periods before and after the use of CL was not significant (p=0.213). The occurrence of AE showed association with the following characteristics: anesthetic risk of the patient, length of stay, surgery time and classification of the procedure according to the potential for contamination. Considering the proportion of deaths, there was a significant reduction in deaths (p=0.007) in patients whose CL was used when compared to those without the use of the instrument. There was no significant association between the presence of CL and the occurrence of AE. It was concluded that the presence of CL in the medical record did not guarantee an expected reduction in the incidence of AE. CONCLUSION: however, it is believed that the use of the instrument integrated with other patient safety strategies can improve the safety/quality of surgical care in the long term.

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ABSTRACT Objective: the study evaluated the effect of using the safe surgery checklist (CL) on the incidence of adverse events (AE). Methods: cross-sectional and retrospective research with 851 patients undergoing surgical procedures in 2012 (n=428) and 2015 (n=423), representing the periods before and after CL implantation. The AE incidences for each year were estimated and compared. The association between the occurrence of AE and the presence of CL in the medical record was analyzed. Results: a reduction in the point estimate of AE was observed from 13.6% (before using the CL) to 11.8% (with the use of the CL). The difference between the proportions of AE in the periods before and after the use of CL was not significant (p=0.213). The occurrence of AE showed association with the following characteristics: anesthetic risk of the patient, length of stay, surgery time and classification of the procedure according to the potential for contamination. Considering the proportion of deaths, there was a significant reduction in deaths (p=0.007) in patients whose CL was used when compared to those without the use of the instrument. There was no significant association between the presence of CL and the occurrence of AE. It was concluded that the presence of CL in the medical record did not guarantee an expected reduction in the incidence of AE. Conclusion: however, it is believed that the use of the instrument integrated with other patient safety strategies can improve the safety/quality of surgical care in the long term.

RESUMO Objetivo: o estudo objetivou avaliar o efeito da utilização do checklist (CL) de cirurgia segura na incidência de eventos adversos (EA). Método: pesquisa transversal e retrospectiva com 851 pacientes submetidos a procedimentos cirúrgicos nos anos de 2012 (n=428) e 2015 (n=423), representando os períodos antes e após a implantação do CL. As incidências de EA para cada ano foram estimadas e posteriormente comparadas. Também foi analisada a associação entre a ocorrência do EA e a presença do CL no prontuário. Resultados: observou-se uma redução na estimativa pontual de EA de 13,6% (antes do uso do CL) para 11,8% (com a utilização do CL). No entanto, a diferença entre as proporções de EA nos períodos antes e após a utilização do CL não foi significativa (p=0,213). A ocorrência do EA mostrou associação significativa às seguintes características: risco anestésico do paciente, tempo de internação, tempo de cirurgia e classificação do procedimento segundo o potencial de contaminação. Considerando a proporção de óbitos ocorridos nas amostras, observou-se uma redução significativa de mortes (p=0,007) em pacientes cujo CL foi utilizado quando comparados aqueles sem o uso do instrumento. Não foi verificada associação significativa entre a presença do CL no prontuário e a ocorrência do EA de forma geral. Conclusão: a presença do CL no prontuário não garantiu uma redução esperada na incidência de EA. No entanto, acredita-se que o uso do instrumento integrado às demais estratégias de segurança do paciente possa melhorar a segurança/qualidade da assistência cirúrgica em longo prazo.

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BACKGROUND: Currently, adolescents' lifestyle is commonly characterized by physical inactivity, sedentary behavior, and inappropriate eating habits in general. A person-oriented approach as Latent Class Analysis (LCA) can offer more insight than a variable-centered approach when investigating lifestyle practices, habits, and behaviors of adolescent population. OBJECTIVE: The aim of the present study was to assess which variables are mostly used to represent the physical activity level, sedentary behavior SB) and nutritional habit in the adolescents' lifestyle in studies that used the LCA. DESIGN: Scoping review. METHODS: The study was a performed in accordance with the proposed criteria for systematic reviews and meta-analyses-Preferred Reporting Items for Systematic Reviews and Meta-Analyses and registered in PROSPERO (CRD42018108444). The original articles were searched in MEDLINE/PubMed, Scopus, ScienceDirect, Web of Science, PsycINFO, and SPORTdiscus. The Quality Assessment Tool analyzed the risk of bias of the included studies. RESULTS: 30 original articles were selected. The physical activity level (28 studies), SB and nutritional habits (18 studies) were the most common variable used to evaluate the adolescent's lifestyle by LCA model. Specifically, physical inactivity and high SB were the manifest variables with higher frequency in the negative latent classes (LCs) in adolescent girls. On the other hand, physical exercises and sports were activities more commonly labeled as positive LCs. CONCLUSIONS: The LCA models of the most of selected studies showed that physical inactivity, high SB were the most common in the LCs with negative characteristics of the adolescents' lifestyle. Better understanding the results of analyzes of clusters of multivariate behaviors such as the LCA can help to create more effective strategies that can make the lifestyle of adolescents healthier.

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In studies of cancer survival, Population-Based Cancer Registries (PBCRs) can provide an overview of the disease for places that have this source of information available. In Brazil, PBCR is officially available in 22 state capitals and 8 cities in the interior of the country. PBCR data from Cuiabá and Várzea Grande, state of Mato Grosso, in Midwestern Brazil, were used to estimate the survival rate of colon (C18), rectosigmoid junction (C19) and rectum (C20) cancer cases diagnosed in 2000-2009 according to the International Classification of Diseases, 10th Revision. Five-year survival rate was estimated by the unbiased and consistent net survival estimator, which is used in the country estimates of the global surveillance of cancer survival programme CONCORD Group, for all cases, and also by sex, age group, diagnosis period and place of residence. The probability of death and the number of years of life lost to illness were also estimated. The estimated standardised 5-year survival rate for colorectal cancer was 45.46% (95% CI: 43.09%-47.96%) in the cities of Cuiabá and Várzea Grande. There was no difference between the curves when the survival rate was assessed by diagnostic period (2000-2004 and 2005-2009), sex, age group or city of residence. The gross 5-year probability of death from the disease was 51.2%, accounting for 6.4% of the gross probability of death from other causes, with 2.07 being the years of life lost to illness. The results obtained for Cuiabá and Várzea Grande are compatible with survival rates estimated for Brazil in the CONCORD study, but demonstrate the need to identify reasons why we continue to have low survival rates when compared to most countries involved in the global study mentioned. The results may reflect late diagnosis, difficult access and delays in starting treatment.

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BACKGROUND: Female adolescents are considered a risk group for cardiometabolic disease due to their lifestyle (LS). OBJECTIVE: To evaluate the association between LS classes and body composition groups with cardiometabolic disease risk factors and pro- and anti-inflammatory biomarkers in female adolescents. METHODS: This cross-sectional study was carried out with female adolescents aged 14 to 19 years, from Viçosa-MG, Brazil. Latent class analysis assessed LS classes. Kinanthropometric measurements were taken together with the body fat percentage (BF%), being analyzed by the Dual Energy X-ray Absorptiometry (DEXA) equipment. Blood pressure and biochemical parameters were analyzed in the Health Division of the Federal University of Viçosa. The pro- and anti-inflammatory biomarkers were analyzed using Luminex technology. Associations with biomarkers were estimated by multiple linear regression. RESULTS: 405 female adolescents were evaluated. The majority, 82.57%, 72.90%, and 65.31%, were classified as inactive by the number of steps, with high screen and cell phone time, respectively. Furthermore, 41.55% did meet the minimum of 60 minutes of moderate-to-vigorous physical activity (MVPA) and 54.69% had high values of BF% (DEXA). The "Sedentary & Inactive LS" class together with the high levels of weight and BF% were associated with increased levels of blood pressure, lipid profile, and uric acid. It was also found that "Inactive & Sedentary LS", high BF%, insulin resistance, and ultra-sensitive C-reactive protein were associated with the concentrations of proinflammatory biomarkers of tumor necrosis factor-α, interleukin-6, and leptin. CONCLUSION: We concluded that female adolescents with overweight/obese and high BF% presented higher values of anthropometric indicators, levels of blood pressure, concentration of uric acid and hs-CRP, and lower concentration of HDL. Inactive and Sedentary lifestyle of these girls, along with excess body fat, insulin resistance, and higher concentrations of hs-CRP were associated with the higher concentration proinflammatory markers.

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Mortality due to colorectal cancer is increasing in Brazil, but an organised approach to screening and prevention is lacking. Considering the importance of this disease, the present study examines recent mortality trends of colorectal cancer mortality in the meso- and microregions in the state of Mato Grosso with the objective of analysing spatiotemporal trends to help guide the allocation of health services related to this type of cancer. Mortality data from the Brazilian national public health system from 1996 to 2015 were analysed investigating spatiotemporal trends using Conditional Autoregressive (CAR) models, a class of Bayesian hierarchical models that rely on Markov Chain Monte Carlo (MCMC) simulations. Convergence issues arose with several types of CAR models, but notably not with the linear variant, which models the mortality within each spatial region as a linear function of time. Men and women of all ages displayed higher and increasing mortality rates in the Cuiabá and Rondonópolis microregions. Additional regions of increasing mortality were found for specific age and gender strata. It was concluded that spatiotemporal modelling is a useful tool for the characterisation of diseases, including cancer, which are influenced by several factors and need to be monitored over space and time. The combination of spatial and temporal analyses of mortality shown in this paper unveils important information regarding the small areas dynamics, which may guide discussions, regulation and application of decentralised public health policies.

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OBJECTIVE: to identify adherence to the safe surgery checklist from its filling out in a general referral hospital in the interior of Minas Gerais state, as well as to verify factors associated with its use. METHODS: this is a retrospective, documentary, cross-sectional study with a quantitative approach. Data collection was performed through a retrospective review of medical records of patients undergoing surgery within one year. Patients of all specialties, aged 18 years or older, and with hospitalization period equal to or greater than 24 hours were included. The probabilistic sample was composed of 423 cases. RESULTS: the checklist was present in 95% of the medical records. However, only 67.4% of them were completely filled out. The presence of the checklist in the medical record was significantly associated with the anesthetic risk of the patient. There was no difference in the filling out percentage among the three checklist moments: before anesthetic induction (sign in), before surgical incision (time out or surgical pause), and before the patient leaves the operating room (sign out). There were also no significant differences regarding the filling out percentage of the surgeon's responsibility items. Considering the surgical procedure performed, inconsistencies were found in the laterality item. CONCLUSION: despite the high percentage of medical records with checklist, the presence of incompleteness and inconsistency may compromise the expected results in the safety of the surgical patient.

OBJETIVO: identificar a adesão ao checklist de cirurgia segura, a partir do seu preenchimento, em um hospital geral de referência do interior do Estado de Minas Gerais, bem como, verificar os fatores associados à sua utilização. MÉTODOS: trata-se de estudo transversal, documental, retrospectivo de abordagem quantitativa. A coleta de dados foi realizada por meio da revisão retrospectiva de prontuários de uma amostra de pacientes operados no período de um ano. Foram incluídos os atendimentos de pacientes cirúrgicos de todas as especialidades, com idade de 18 anos ou mais, e período de internação igual ou maior do que 24 horas. A amostra probabilística foi de 423 casos. RESULTADOS: o checklist estava presente em 95% dos prontuários. Porém, apenas 67,4% deles estavam com preenchimento completo. A presença do checklist no prontuário apresentou associação significativa com o risco anestésico do paciente. Não houve diferença no percentual de preenchimento entre os três momentos do checklist: antes da indução anestésica (sign in), antes da incisão cirúrgica (time out ou parada cirúrgica) e antes do paciente deixar a sala de cirurgia (sign out). Também não foram encontradas diferenças significativas em relação ao percentual de preenchimento dos itens de responsabilidade do cirurgião. Considerando o procedimento cirúrgico realizado, foram encontradas incoerências no item lateralidade. CONCLUSÃO: apesar do elevado percentual de prontuários com checklist, a presença de incompletude e incoerência pode comprometer os resultados esperados na segurança do paciente cirúrgico.

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