Assuntos
Dermatologia/métodos , Dermatopatias/complicações , Dermatopatias/diagnóstico , Dermatopatias/epidemiologia , Dermatopatias/tratamento farmacológico , Dermatopatias/genética , Dermatopatias/imunologia , Dermatopatias/patologia , Dermatopatias/terapia , Pele/anatomia & histologia , Pele/embriologia , Pele/imunologiaRESUMO
The lines of Blaschko represent a pattern followed by many skin disorders. We review the clinical and histologic features of X-linked, congenital/nevoid, and acquired skin diseases that follow these lines. We also include cutaneous disorders that have a linear distribution but do not follow Blaschko's lines. Finally, we differentiate Blaschko's lines from other patterns on the skin such as dermatomes and Langer's lines.
Assuntos
Feminino , Masculino , Humanos , História do Século XX , Alemanha , Dermatopatias/história , Dermatopatias/patologia , Neoplasias Cutâneas/história , Neoplasias Cutâneas/patologia , Pele/patologiaRESUMO
PART I - Skin disorders in which a radiograph may detect associated bony changes or abnormalities of calcification are discussed. They are grouped into eight categories: (1) inherited diseases (e.g., alkaptonuria, neurofibromatosis); (2) congenital disorders (e.g., Sturge-Weber and Proteus syndromes); (3) inflammatory conditions (e.g., dermatomyositis, sarcoidosis); (4) infections (e.g., dental sinus, syphilis); (5) neoplasias (e.g., histiocytosis, mastocytosis); (6) drug- and environment-induced (e.g., acroosteolysis, retinoid toxicity); (7) calcinosis cutis; and (8) osteoma cutis. Part I of our review discusses the first two categories.
Assuntos
Humanos , Anormalidades Múltiplas/diagnóstico por imagem , Anormalidades Múltiplas/patologia , Anormalidades da Pele , Calcinose/diagnóstico por imagem , Calcinose/patologia , Dermatopatias/complicações , Dermatopatias/diagnóstico por imagem , Dermatopatias/genética , Dermatopatias/patologia , Doenças Genéticas Inatas/diagnóstico por imagem , Doenças do Desenvolvimento Ósseo/diagnóstico por imagem , Doenças Ósseas/complicações , Osso e Ossos/diagnóstico por imagem , Osso e Ossos/patologia , Pele/diagnóstico por imagemRESUMO
A review of the basics of pigment cell biology is followed by a discussion of the characteristics of several disorders of hypopigmentation. By determining such features as inheritance pattern, time of onset (congenital, childhood, adulthood), natural history (stable vs progressive), type of pigment loss (diffuse or circumscribed), distribution of lesions (generalized vs localized), degree of pigment loss (incomplete or complete), number of melanocytes, if any, in biopsy specimens of affected areas, type of melanocytic dysfunction, and associated inflammation or infection, one can classify the disorders of hypopigmentation. The proposed pathophysiology for each disorder of hypomelanosis is presented.