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1.
Front Nutr ; 9: 781540, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35308279

RESUMO

Introduction: Bioethics and nutrition are essential issues in end of life, advanced dementia, life-sustaining therapies, permanent vegetative status, and unacceptably minimal quality of life. Even though artificially administered nutrition (AAN), for this type of health condition, does not improve quality of life and extension of life, and there is evidence of complications (pulmonary and gastrointestinal), it has been used frequently. It had been easier considering cardiopulmonary resuscitation as an ineffective treatment than AAN for a healthy team and/or family. For this reason, many times, this issue has been forgotten. Objectives: This study aimed to discuss bioethical principles and AAN in the involved patients. Discussion: The AAN has been an essential source of ethical concern and controversy. There is a conceptual doubt about AAN be or not be a medical treatment. It would be a form of nourishment, which constitutes primary care. These principles should be used to guide the decision-making of healthcare professionals in collaboration with patients and their surrogates. Conclusions: This difficult decision about whether or not to prescribe AAN in patients with a poor prognosis and without benefits should be based on discussions with the bioethics committee, encouraging the use of advanced directives, education, and support for the patient, family, and health team, in addition to the establishment of effective protocols on the subject. All of this would benefit the most important person in this process, the patient.

3.
Case Rep Hematol ; 2017: 8394732, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28326208

RESUMO

Hematopoietic stem cell transplantation (HSCT) is an important treatment option for children with severe and refractory sickle cell disease (SCD) with debilitating clinical complications. HSCT with cells from the bone marrow of a HLA-identical sibling used in SCD has a low mortality risk, high cure rate, and high event-free survival rate after a median follow-up of 5-6 years. However, matched donors are found in only about 20% of the patients. A boy aged 8 years with SCD had a sister, <2 years old, a fully compatible donor. The boy met all eligibility criteria to undergo HSCT, and he was suffering from cognitive and neurologic impairment due to ischemic events. A Bioethical Committee jointly discussed the ethical issues on this case after a pediatric evaluation released the very young sister for donation. The justification was that the sister would benefit from the donation too because of the greater likelihood of survival and cure and less suffering of her brother. The parents were informed about the risks and benefits for both children, and the family was psychologically evaluated. After their consent, HSCT was performed and the patient is cured from SCD. The complication for the donor was the need for blood transfusion.

6.
Einstein (Säo Paulo) ; 8(2)abr.-jun. 2010. ilus
Artigo em Inglês, Português | LILACS | ID: lil-550959

RESUMO

Pericardial cysts account for 12-18% of all mediastinal masses. They are usually asymptomatic and incidentally detected. However, when large, they can cause symptoms. Most pericardial cysts are located in the right cardiophrenic angle, but they can be anywhere in the mediastinum. We reported a pleuropericardial cyst torsion after physical stress, a very rare complication of this condition. The diagnosis was made by computed tomography and confirmed by video-assisted thoracoscopy.


Cistos pericárdicos constituem 12-18% de todas as massas mediastinais. Geralmente, são assintomáticos e detectados incidentalmente, podendo manifestar sintomas quando alcançam um tamanho aumentado. Na maioria das vezes, estão situados no seio cardiofrênico direito, mas podem ocupar outra localização no mediastino. Neste artigo, relatamos uma torção de cisto pleuropericárdico após esforço físico, uma complicação raríssima dessa condição, cujo diagnóstico foi realizado por meio da tomografia computadorizada do tórax e confirmado posteriormente por videotoracoscopia.


Assuntos
Humanos , Diagnóstico por Imagem , Cisto Mediastínico , Anormalidade Torcional
7.
Einstein (Sao Paulo) ; 8(2): 228-31, 2010 Jun.
Artigo em Inglês, Português | MEDLINE | ID: mdl-26760009

RESUMO

Pericardial cysts account for 12-18% of all mediastinal masses. They are usually asymptomatic and incidentally detected. However, when large, they can cause symptoms. Most pericardial cysts are located in the right cardiophrenic angle, but they can be anywhere in the mediastinum. We reported a pleuropericardial cyst torsion after physical stress, a very rare complication of this condition. The diagnosis was made by computed tomography and confirmed by video-assisted thoracoscopy.

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