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OBJECTIVES: to evaluate the profile of emergency care of trauma patients at Hospital Universitário Evangélico Mackenzie (HUEM) during the period of restrictive measures due to COVID-19 (03/13/2021 to 04/05/2021), and compare to the same period at the beginning of the pandemic, in 2020, and before the pandemic, in 2019. METHODS: quantitative and descriptive observational cross-sectional study. The final sample of 8,338 was analyzed in terms of date, gender, age and service responsible for providing care; the traumas were analyzed according to the etiology and conduct of the treatment and outcome. RESULTS: there was a percentage increase in non-traumatic emergency care during the pandemic, and the medical clinic held a third of admissions in 2021. There was a reduction in trauma care, since in 2019 traumas were responsible for 44.9% of admissions and by 23.5% in 2021. There was a significant difference in the proportion between the attendance of men and women, and the percentage of men victims of trauma was higher than in the pre-pandemic periods. There was a reduction in absolute numbers, with statistical significance, in traffic accidents, falls from the same level, burns, general blunt trauma and sports and leisure trauma. The proportion of conservative treatments with hospital discharge reduced. There was a significant difference in the number of deaths, decreasing in 2020 but increasing in 2021. CONCLUSION: there was a reduction in trauma care during the pandemic, but the profile remained the adult male victim of a traffic accident. More severe traumas were admitted, resulting in an increase in surgical treatment, hospitalizations and deaths.

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ABSTRACT Objectives: to evaluate the profile of emergency care of trauma patients at Hospital Universitário Evangélico Mackenzie (HUEM) during the period of restrictive measures due to COVID-19 (03/13/2021 to 04/05/2021), and compare to the same period at the beginning of the pandemic, in 2020, and before the pandemic, in 2019. Methods: quantitative and descriptive observational cross-sectional study. The final sample of 8,338 was analyzed in terms of date, gender, age and service responsible for providing care; the traumas were analyzed according to the etiology and conduct of the treatment and outcome. Results: there was a percentage increase in non-traumatic emergency care during the pandemic, and the medical clinic held a third of admissions in 2021. There was a reduction in trauma care, since in 2019 traumas were responsible for 44.9% of admissions and by 23.5% in 2021. There was a significant difference in the proportion between the attendance of men and women, and the percentage of men victims of trauma was higher than in the pre-pandemic periods. There was a reduction in absolute numbers, with statistical significance, in traffic accidents, falls from the same level, burns, general blunt trauma and sports and leisure trauma. The proportion of conservative treatments with hospital discharge reduced. There was a significant difference in the number of deaths, decreasing in 2020 but increasing in 2021. Conclusion: there was a reduction in trauma care during the pandemic, but the profile remained the adult male victim of a traffic accident. More severe traumas were admitted, resulting in an increase in surgical treatment, hospitalizations and deaths.

RESUMO Objetivo: avaliar o perfil de atendimento emergencial dos pacientes vítimas de trauma do Hospital Universitário Evangélico Mackenzie (HUEM) durante o período de medidas restritivas devido à COVID-19 (13/03/2021 a 05/04/2021) e comparar ao mesmo período no início da pandemia, em 2020, e antes da pandemia, em 2019. Métodos: estudo transversal observacional quantitativo e descritivo. A amostra final de 8.338 foi analisada quanto a data, sexo, idade e serviço responsável pelo atendimento; os traumas foram analisados conforme a etiologia e a conduta do tratamento e desfecho. Resultados: houve aumento percentual no atendimento a urgências não traumáticas durante a pandemia, e a clínica médica deteve um terço das admissões em 2021. Ocorreu redução nos atendimentos por trauma, visto que em 2019 os traumas foram responsáveis por 44,9% das admissões e por 23,5% em 2021. Houve diferença significativa na proporção entre os atendimentos de homens e mulheres, sendo que o percentual de homens vítimas de traumas foi maior do que os períodos pré pandêmicos. Observou-se redução em números absolutos, com significância estatística, nos eventos de trânsito, queda de mesmo nível, queimaduras, traumas contusos gerais e traumas esportivos e de lazer. A proporção de tratamentos conservadores com alta hospitalar reduziu. Houve diferença significativa na quantidade de óbitos, reduzindo em 2020, mas aumentando em 2021. Conclusão: houve redução do atendimento no trauma durante a pandemia, mas o perfil permaneceu sendo o homem adulto vítima de eventos de trânsito. Traumas de maior gravidade foram admitidos, resultando no aumento de tratamento cirúrgico, internamentos e óbitos

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O trauma é a 5ª. causa de morte no mundo e, na população com menos de 40 anos, é a maior causa de óbitos. O abdome é região frequentemente lesada e requer tratamento cirúrgico com frequência. Em se tratando de trauma contuso, exames de imagem oferecem diagnóstico mais acurado conduzindo tratamento mais adequado. O objetivo deste estudo foi avaliar a relação dos achados tomográficos, do exame físico e a prevalência das lesões. Foram selecionados 39 politraumatizados e vítimas de trauma abdominal contuso, através de um estudo prospectivo. Foram comparados exame físico e o achado tomográfico. Em conclusão, mostrou-se que a avaliação clínica isoladamente pode fazer com que lesões passem desapercebidas; a tomografia computadorizada teve boa sensibilidade e especificidade devendo ser realizada para diagnosticar e melhor guiar a terapêutica.

Trauma is the 5th cause of death in the world and, in the population under 40 years old, it is the biggest cause of death. The abdomen is a frequently injured region and often requires surgical treatment. In the case of blunt trauma, imaging tests offer a more accurate diagnosis leading to more appropriate treatment. The aim of this study was to evaluate the relationship between tomographic and physical examination findings and the prevalence of lesions. Thirty-nine polytraumatized and victims of blunt abdominal trauma were selected through a prospective study. Physical examination and tomographic findings were compared. In conclusion, it has been shown that clinical assessment alone can make lesions go unnoticed; computed tomography had good sensitivity and specificity and should be performed to diagnose and better guide therapy.

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A apendicite aguda representa a causa mais comum de emergência abdominal. O diagnóstico é predominantemente clínico, mas pode ser desafiador. Os objetivos deste estudo foram avaliar a associação entre a pontuação do escore de Alvarado, achados cirúrgicos e o resultado anatomopatológico do apêndice.Trata-se de estudo transversal, quantitativo e descritivo, que obteve informações por meio de prontuários eletrônicos de todos os pacientes que foram operados por suspeita de apendicite. Foram analisados 42 prontuários. Desses, 6 foram excluídos, resultando em uma amostra de 36 pacientes. Com relação à escala de Alvarado, o dado mais frequente foi a dor à palpação em FID, apendicectomia negativa foi de 13,9%. À inspeção cirúrgica, a maioria das apendicectomias estavam em estados iniciais da doença, com hiperemia e edema. Os compatíveis com grau I foram classificaram entre 5 e 8 na escala. Foi possível observar que os que tiveram apendicectomias negativas tinham tendência de graus mais altos. Em conclusão, a escala de Alvarado representa ferramenta útil na triagem de pacientes com suspeita de apendicite, podendo orientar as condutas a serem aplicadas.

Acute appendicitis represents the most common cause of abdominal emergence. Diagnosis is predominantly clinical but can be challenging. The objectives of this study were to evaluate the association between the Alvarado score, surgical findings and the anatomopathological result of the appendix. This is a cross-sectional, quantitative and descriptive study, which obtained information through electronic medical records of all patients who were operated on for suspected appendicitis. 42 medical records were analyzed. Of these, 6 were excluded, resulting in a sample of 36 patients. Regarding the Alvarado scale, the most frequent data was pain on palpation in FID, negative appendectomy was 13.9%. Upon surgical inspection, most appendectomies were in the early stages of the disease, with hyperemia and edema. Grade I compatibles were rated between 5 and 8 on the scale. It was possible to observe that those who had negative appendectomies tended to have higher grades. In conclusion, the Alvarado scale represents a useful tool in the screening of patients with suspected appendicitis and can guide the procedures to be applied.

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A tetralogia de Fallot é a cardiopatia congênita cianótica mais comum. Caracteriza-se por tétrade de malformações anatômicas que incluem estenose pulmonar, defeito do septo ventricular, hipertrofia do ventrículo direito e dextroposição da aorta (cavalgamento da aorta). O objetivo deste estudo foi analisar e descrever as alterações anatômicas cardíacas, tratamento e prognóstico de pacientes com a doença. É revisão narrativa de artigos indexados na base de dados PubMed, Google Acadêmico e LILACS utilizando os descritores "tetralogy of Fallot", "congenital heart disease", "cyanotic disease". Em conclusão, a tetralogia de Fallot é cardiopatia congênita comum e com prognóstico ruim caso não seja realizado diagnóstico e tratamento precoces. O seguimento médico contínuo e próximo ao paciente é importante para acompanhar a evolução e programar novas intervenções caso necessárias.

Tetralogy of Fallot is the most common cyanotic congenital heart disease. It is characterized by tetrads of anatomical malformations that include pulmonary stenosis, ventricular septal defect, right ventricular hypertrophy, and aortic dextroposition (aortic cavalcade). The objectives of this study were to analyze and describe cardiac anatomical changes, treatment and prognosis of patients with the disease. It was a narrative review of articles indexed in PubMed, Academic Google and LILACS databases using the descriptors "Tetralogy of Fallot", "congenital heart disease", "cyanotic disease". In conclusion, tetralogy of Fallot is a common congenital heart disease with poor prognosis if early diagnosis and treatment are not performed. Continuous medical follow-up and to be close to the patient are important to monitor the evolution and schedule new interventions if necessary.

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A hemoglobina glicosilada é amplamente utilizada em estudos clínicos para avaliação e acompanhamento do diabete melito. O objetivo deste estudo foi analisar os níveis de hemoglobina glicosilada (HbA1c) no pré e pós-operatório de pacientes obesos diabéticos submetidos ao bypass gastrointestinal. É prospectivo, observacional e transversal, incluiu a análise de 92 prontuários de pacientes submetidos ao bypass. Em relação à hemoglobina glicosilada, houve diferença estatística (p<0,001) entre os valores pré e pós (6 meses) com redução média de 0,73. Em conclusão, a redução significativa da hemoglobina glicosilada após 6 meses do bypass, demonstra que ela é bom fator preditivo para avaliação da redução do diabete pós-tratamento cirúrgico.

Glycosylated hemoglobin is widely used in clinical studies for the evaluation and follow-up of diabetes mellitus. The aim of this study was to analyze the pre and postoperative levels of glycosylated hemoglobin (HbA1c) in obese diabetic patients undergoing gastrointestinal bypass. It is prospective, observational and cross-sectional, including the analysis of 92 medical records of patients undergoing bypass. Regarding glycosylated hemoglobin, there was a statistical difference (p<0,001) between pre and post values (6 months) with a mean reduction of 0.73. In conclusion, the significant reduction in glycosylated hemoglobin after 6 months of bypass demonstrates that it is a good predictive factor for assessing the reduction in diabetes after surgical treatment.

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A endometriose é condição ginecológica crônica, caracterizada pela presença de tecido semelhante ao endométrio fora da cavidade uterina. Apesar da causa ser complexa e pouco elucidada, estudos sugerem fortes associações entre endometriose e anormalidades no sistema imunológico. Assim é importante determinar a prevalência de fator anti nuclear (FAN) e anti-DNA em pacientes diagnosticadas com endometriose e suas associações. Foi realizado estudo transversal analítico para elucidar o tema. A amostra foi composta por 94 pacientes com diagnóstico de endometriose confirmado por videolaparoscopia e biópsia com estudo anatomopatológico. Como grupo controle foram utilizados 91 pacientes pareados em idade e gênero. Em conclusão, pacientes com endometriose apresentam maior prevalência de FAN em relação ao grupo controle. A positividade do FAN não tem associação com o estadiamento ASRM da endometriose e gravidade da doença. As pacientes com endometriose não apresentaram reatividade para o anticorpo anti-ds-DNA.

Endometriosis is a chronic gynecological condition, characterized by the presence of tissue similar to the endometrium outside the uterine cavity. Although the etiology is complex and poorly understood, studies suggest strong associations between endometriosis and abnormalities in the immune system. Thus, it is important to determine the prevalence of anti-nuclear factor (ANA) and anti-DNA in patients diagnosed with endometriosis and their associations. An analytical cross-sectional study was carried out to elucidate the topic. The sample consisted of 94 patients with a diagnosis of endometriosis confirmed by videolaparoscopy and biopsy with anatomopathological study. As a control group, 91 patients matched for age and gender were used. In conclusion, patients with endometriosis have a higher prevalence of ANA compared to the control group. ANA positivity is not associated with ASRM staging of endometriosis and disease severity. Patients with endometriosis did not show reactivity to anti-ds-DNA antibody.

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Racional: O impacto da infeção congênita e perinatal pelo CMV na saúde pública é muito relevante, sendo a infecção congênita mais predominante, porém pouco abordada. Objetivos: Avaliar o perfil dos pacientes com diagnóstico positivo para infecção congênita e perinatal por citomegalovírus. Métodos: Estudo observacional, analítico, transversal, com coleta de dados retrospectiva. Os dados foram obtidos segundo critérios demográficos, imunológicos, virológicos, terapêuticos e de análise dos exames de imagem.Resultados: Foram coletados dados de 35 pacientes que inicialmente receberam o diagnóstico, entretanto somente 17 preenchiam os critérios de inclusão. Conclusões: A amostra estudada foi de casos sintomáticos e reflete proporcionalmente pouco de uma doença tão prevalente. Isto se deve a dificuldade diagnóstica maternofetal; portanto, é importante enfocar e investir em pesquisa e novas ferramentas para um diagnóstico precoce.

Background: The impact of congenital and perinatal CMV infection on public health is very relevant, with congenital infection being the most prevalent, but little addressed. Objective: To evaluate, through the analysis of medical records, the profile of patients with diagnosis of congenital or perinatal cytomegalovirus infection during the stipulated study time. Methods: Observational study, analytical, cross-sectional, with retrospective data collection. The data were obtained according to demographic, immunologic, virologic and therapeutic criteria, as well as imaging exams analysis. Results: Data were collected from 35 patients who initially received the congenital or perinatal infection diagnosis during the time stipulated by the study, but only 17 met the inclusion criteria. Conclusions: The studied sample of symptomatic patients proportionally reflects little of such a prevalent disease. This happens because of the difficult mother-fetus diagnosis. Therefore, it is important to focus and invest in research and new tools seeking the early diagnosis.

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BACKGROUND: Crusts in 7th follow-up day: G1 yes; G2 no; G3 no (left to right). Bespite all the advances in medicine and the wide variety of dressings available, the treatment of burn wounds still represents an important medical challenge. The pinus cellulose membrane dressing is a biomaterial with characteristics similar to those of bacterial cellulose, but with lower cost. AIM: To evaluate the efficacy of pinus nanocellulose membrane on healing of deep second degree burns in rats and compare with Membracel®. METHOD: Thirty male Wistar rats were submitted to deep second degree burn in dorse, with boiling water at 97o C for 20 s, generating a 314 mm² area wound. The animals were distributed in three dressing groups (n=10): group 1 - simple gauze; group 2 - bacterial cellulose membrane (Membracel®); and group 3 - pinus cellulose membrane. They were evaluated for 20 days to verify clinical condition, macro and microscopic appearance and wound contraction. RESULTS: All of them remained clinically well with no differences in weight. Crusts were observed in group 1, and none in groups 2 and 3. Regarding to scar contraction, groups 2 and 3 were similar, better than group 1. Microscopic analysis showed predominance of advanced healing degree in groups 1 and 3, and initial in group 2. Mature collagen was predominant in all groups. CONCLUSION: The pinus nanocellulose membrane is effective in the treatment of experimental second degree burn in rats and its effectiveness is similar to that of the bacterial nanocellular membrane.

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