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J Toxicol ; 2012: 951568, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22619673

RESUMO

The effect of residual concentrations of organophosphate pesticide chlorpyrifos (Lorsban 4E) on the activity of the acetylcholinesterase enzyme and oxygen : nitrogen ratio in the mussel Aulacomya ater was analyzed. Toxicity tests show a sensitivity to the pesticide in the bivalve estimated at 16 µg L(-1) (LC(50-96 hours)). Concentrations between 0.2 and 1.61 µg L(-1) were able to inhibit significantly the AChE activity, and concentrations between 0.8 and 1.61 µg L(-1) stimulate ammonia excretion and decrease oxygen : ammonia-N (O : N) ratio, with respect to the control group. A. ater proved to be a species sensitive to pesticide exposure and easy to handle in lab conditions. Thus, it is recommended as a bioindicator for use in programs of environmental alertness in the Eastern South Pacific coastal zone.

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