RESUMO

Cationic derivatives of 5,10,15-tris[4-(pyridin-4-ylsulphanyl)-2,3,5,6-tetrafluorophenyl]-corrolategallium(III)pyridine and 5,10,15-tris[4-(pyridin-2-ylsulfanyl)-2,3,5,6-tetrafluorophenyl]-correlategallium(III)pyridine were synthesized and their photosensitizing properties against the naturally bioluminescent Gram-negative bacterium Allivibrio fischeri were evaluated. The cationic corrole derivatives exhibited antibacterial activity at micromolar concentrations against this Gram-negative bacterium strain.

Assuntos

Aliivibrio fischeri/efeitos dos fármacos , Antibacterianos/farmacologia , Luminescência , Porfirinas/farmacologia , Antibacterianos/química , Cromatografia em Camada Fina , Ensaio de Unidades Formadoras de Colônias , Testes de Sensibilidade Microbiana , Porfirinas/química