RESUMO
Trescientos noventa y cuatro pacientes con úlcera duodenal diagnosticada endoscópica fueron randomizados para recibir ranitidina 150 mg bid o ranitidina 300 mg bid en un estudio multicéntrico, prospectivo, doble-ciego, llevado a cabo en 7 países latinoamericanos. La endoscopía a las 4 semanas mostró curación completa de las úlceras en 171 de 196 pacientes (87.2%) tratados con ranitidina 150 mg bid y 178 de 198 (89.9%) tratados con ranitidina 300 mg bid. Ambos regímenes de tratamientos fueron igualmente efectivos, reduciendo rápidamente la incidencia de los síntomas ulcerosos. Es probable que el regimen de dosis elevadas con ranitidina sea adecuado en pacientes con enfermedad ulcerosa severa
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Ranitidina/uso terapêutico , Úlcera Duodenal/tratamento farmacológico , Ensaios Clínicos como Assunto , Método Duplo-Cego , México , Estudos Multicêntricos como Assunto , Panamá , Ranitidina/administração & dosagem , América do Sul , Fatores de TempoRESUMO
Trescientos noventa y cuatro pacientes con úlcera duodenal diagnosticada endoscópica fueron randomizados para recibir ranitidina 150 mg bid o ranitidina 300 mg bid en un estudio multicéntrico, prospectivo, doble-ciego, llevado a cabo en 7 países latinoamericanos. La endoscopía a las 4 semanas mostró curación completa de las úlceras en 171 de 196 pacientes (87.2%) tratados con ranitidina 150 mg bid y 178 de 198 (89.9%) tratados con ranitidina 300 mg bid. Ambos regímenes de tratamientos fueron igualmente efectivos, reduciendo rápidamente la incidencia de los síntomas ulcerosos. Es probable que el regimen de dosis elevadas con ranitidina sea adecuado en pacientes con enfermedad ulcerosa severa (AU)
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Úlcera Duodenal/tratamento farmacológico , Ranitidina/uso terapêutico , Método Duplo-Cego , Ensaios Clínicos como Assunto , América do Sul , México , Panamá , Estudos Multicêntricos como Assunto , Fatores de Tempo , Ranitidina/administração & dosagemRESUMO
394 patients with endoscopically diagnosed duodenal ulcer were randomly allocated to treatment with ranitidine 150 bid o ranitidine 300 mg bid in a prospective double-blind multicenter trial conducted in seven LatinoAmerican countries. Endoscopy at 4 weeks showed complete ulcer healing en 171 of 196 patients (87.2%) treated with ranitidine 150 mg bid and 178 of 198 (89.9%) treated with ranitidine 300 mg bid. Both treatment regimens were equally effective at rapidly reducing the incidence of ulcer-related symptoms. It is possible that higher dosage regimen of ranitidine would be useful in patients with more severe duodenal ulcer disease.
Assuntos
Úlcera Duodenal/tratamento farmacológico , Ranitidina/administração & dosagem , Adulto , Método Duplo-Cego , Esquema de Medicação , Feminino , Humanos , Masculino , México , Pessoa de Meia-Idade , Panamá , América do SulRESUMO
394 patients with endoscopically diagnosed duodenal ulcer were randomly allocated to treatment with ranitidine 150 bid o ranitidine 300 mg bid in a prospective double-blind multicenter trial conducted in seven LatinoAmerican countries. Endoscopy at 4 weeks showed complete ulcer healing en 171 of 196 patients (87.2
) treated with ranitidine 150 mg bid and 178 of 198 (89.9
) treated with ranitidine 300 mg bid. Both treatment regimens were equally effective at rapidly reducing the incidence of ulcer-related symptoms. It is possible that higher dosage regimen of ranitidine would be useful in patients with more severe duodenal ulcer disease.
RESUMO
Experimental pancreatic transplantation was performed in dogs using different surgical techniques. Ten dogs underwent whole organ graft with diversion of exocrine secretion by anastomosis of duodenal segment to bladder (six animals) and of duodenum to a jejunal loop (four animals). Segmental pancreatic grafts were performed in 10 dogs with ductal filling with polymer in six animal and duct ligation in four dogs. It is concluded that segmental pancreatic graft with ductal filling with polymer is preferable to the other surgical techniques
Assuntos
Cães , Animais , Transplante de Pâncreas/métodos , Neopreno/administração & dosagem , Transplante de Pâncreas/fisiologiaRESUMO
Experimental pancreatic transplantation was performed in dogs using different surgical techniques. Ten dogs underwent whole organ graft with diversion of exocrine secretion by anastomosis of duodenal segment to bladder (six animals) and of duodenum to a jejunal loop (four animals). Segmental pancreatic grafts were performed in 10 dogs with ductal filling with polymer in six animal and duct ligation in four dogs. It is concluded that segmental pancreatic graft with ductal filling with polymer is preferable to the other surgical techniques (AU)
Assuntos
Cães , Animais , Transplante de Pâncreas/métodos , Transplante de Pâncreas/fisiologia , Neopreno/administração & dosagemRESUMO
Experimental pancreatic transplantation was performed in dogs using different surgical techniques. Ten dogs underwent whole organ graft with diversion of exocrine secretion by anastomosis of duodenal segment to bladder (six animals) and of duodenum to a jejunal loop (four animals). Segmental pancreatic grafts were performed in 10 dogs with ductal filling with polymer in six animals and duct ligation in four dogs. It is concluded that segmental pancreatic graft with ductal filling with polymer is preferable to the other surgical techniques.
Assuntos
Transplante de Pâncreas/métodos , Animais , Cães , Neopreno/administração & dosagem , Transplante de Pâncreas/fisiologiaRESUMO
Experimental pancreatic transplantation was performed in dogs using different surgical techniques. Ten dogs underwent whole organ graft with diversion of exocrine secretion by anastomosis of duodenal segment to bladder (six animals) and of duodenum to a jejunal loop (four animals). Segmental pancreatic grafts were performed in 10 dogs with ductal filling with polymer in six animals and duct ligation in four dogs. It is concluded that segmental pancreatic graft with ductal filling with polymer is preferable to the other surgical techniques.
RESUMO
Experimental pancreatic transplantation was performed in dogs using different surgical techniques. Ten dogs underwent whole organ graft with diversion of exocrine secretion by anastomosis of duodenal segment to bladder (six animals) and of duodenum to a jejunal loop (four animals). Segmental pancreatic grafts were performed in 10 dogs with ductal filling with polymer in six animals and duct ligation in four dogs. It is concluded that segmental pancreatic graft with ductal filling with polymer is preferable to the other surgical techniques.
RESUMO
Se comunica un caso de carcinoma hepatocelular variedad fibrominar, asociado a fenómenos paraneoplásicos, en una mujer de 17 años. La presentación clínica fue con hipertiroidismo y cursó con metástasis pulmonares y en tejido muscular de región glútea. Se revisa la literatura científica, encontrándose sólo un caso relatado con similar cuadro endócrino