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INTRODUCTION: Posterior reversible encephalopathy syndrome (PRES) is an entity characterized by neurologic symptoms such as headaches, altered mental status, seizures and visual changes, and it is associated with white matter vasogenic edema predominantly affecting the posterior occipital and parietal lobes of the brain. CASE REPORT: A 19-year-old patient developed PRES after the use of chemotherapy for a testicular teratocarcinoma and after the development of a blood pressure elevation. DISCUSSION: Few cases described the involvement of the spinal cord in this syndrome. In the majority of these cases, the spinal cord involvement was asymptomatic or with few symptoms of spinal cord disease.
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Perinephric abscesses are life-threatening conditions, which are rarely associated with neoplasms of the kidney or upper tract collecting system. We report, to our knowledge, the first case of squamous carcinoma of the upper tract presenting as a perinephric abscess, diagnosed after radical nephrectomy.
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The aim of the study is to evaluate the effect of simvastatin in erectile dysfunction (ED) secondary to endothelial dysfunction. This study is a double-blind, randomized, placebo-controlled, clinical trial in patients with ED and endothelial dysfunction. Patients were randomized to receive 20 mg simvastatin (n = 21) or placebo (n = 20) daily for 6 months and subsequently 10 mg of vardenafil on demand for 4 weeks. Serum cholesterol, hormone profile, ultrasensitive C-reactive protein, the International Index of Erectile Dysfunction (IIEF) and the ED Index of Treatment Satisfaction were evaluated. There was a significant reduction in serum cholesterol in the treatment group. The hormonal profile remained unaltered. There was no difference in the IIEF between the groups at follow-up, although, at the beginning, 26% of the patients of both groups presented with mild ED and 74% with moderate-to-severe ED; at the end of the 7th month, all patients from the simvastatin group progressed to mild ED, compared with only 83% in the placebo group. There was no statistically significant difference in penile erection after intake of simvastatin or placebo. This study does not support the use of simvastatin as erectogenic medication. Further studies are necessary to verify if simvastatin has any beneficial effect on ED.
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Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Impotência Vasculogênica/tratamento farmacológico , Sinvastatina/uso terapêutico , Adulto , Idoso , Colesterol/sangue , Método Duplo-Cego , Endotélio Vascular/fisiopatologia , Hormônios/sangue , Humanos , Impotência Vasculogênica/fisiopatologia , Masculino , Pessoa de Meia-Idade , Placebos , Sinvastatina/efeitos adversos , Resultado do TratamentoRESUMO
Presentamos un caso clínico de incontinencia urinaria parcial en un paciente de sexo masculino de 17 años y diagnótico de meningomielocele, vejiga neurogénica de baja capacidad y disminución del tono uretral, el cual fue sometido anteriormente a gastrocistoplastia, técnica de Kropp, colocación de un esfínter uretral artificial estático de Lima
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Humanos , Masculino , Adolescente , Bexiga Urinaria Neurogênica/fisiopatologia , Incontinência Urinária/diagnóstico , Incontinência Urinária/cirurgia , Meningomielocele , Bexiga Urinária/cirurgiaRESUMO
Presentamos un caso clínico de incontinencia urinaria parcial en un paciente de sexo masculino de 17 años y diagnótico de meningomielocele, vejiga neurogénica de baja capacidad y disminución del tono uretral, el cual fue sometido anteriormente a gastrocistoplastia, técnica de Kropp, colocación de un esfínter uretral artificial estático de Lima(AU)