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1.
Clin Ter ; 173(3): 198-202, 2022 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-35612329

RESUMO

Purpose: The main purpose of this study was to report a case of cystoid macular edema (CME) after gonioscopy-assisted transluminal trabeculotomy (GATT). Methods: We describe the case of a 73-year-old woman with ocular hypertension and history of cataract surgery combined with posterior vitrectomy and epiretinal membrane peeling 2 years before, who developed CME after uncomplicated GATT procedure. Results: Uneventful GATT surgery was performed in an eye with ocular hypertension. A month after GATT surgery, the patient com-plained of blurry vision. Best corrected visual acuity had deteriorated from 20/20 on Snellen chart, to 20/70. The patient was diagnosed with CME. Treatment with topical non-steroidal anti-inflammatory drug (NSAID) and topical corticosteroids for one month, and oral carbonic anhydrase inhibitor for one week achieved a total CME regression with recovery of a normal macular and foveal architecture. Conclusions: Surgery-induced CME may occur following stand-alone microinvasive glaucoma surgery (MIGS) such as GATT. It would be worthwhile to conduct studies to explore whether the prophylactic use of NSAID and corticosteroids is justified.


Assuntos
Glaucoma de Ângulo Aberto , Edema Macular , Hipertensão Ocular , Trabeculectomia , Corticosteroides/efeitos adversos , Idoso , Anti-Inflamatórios não Esteroides , Feminino , Seguimentos , Glaucoma de Ângulo Aberto/complicações , Glaucoma de Ângulo Aberto/diagnóstico , Glaucoma de Ângulo Aberto/cirurgia , Gonioscopia , Humanos , Pressão Intraocular , Edema Macular/etiologia , Estudos Retrospectivos , Trabeculectomia/efeitos adversos , Trabeculectomia/métodos
2.
Arch Soc Esp Oftalmol (Engl Ed) ; 94(1): 4-11, 2019 Jan.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-30270037

RESUMO

BACKGROUND AND OBJECTIVE: In view of the increasing bacterial resistance to antibiotics, it is necessary to determine it locally in order to serve as a guide in clinical management. The purpose of this study was to characterise the pattern of antibiotic sensitivity in cases of eye infections in a third level ophthalmological institution in Floridablanca (Colombia). MATERIALS AND METHODS: An observational cross-sectional study in which an analysis was made of the culture and antibiogram reports of specimens taken from cases of conjunctivitis, infectious keratitis, and endophthalmitis between January 2013 and June 2016. RESULTS: A total of 833 specimens were positive for bacteria. Considering both gram-positive and gram-negative microorganisms gentamicin, tobramycin, and ciprofloxacin showed high resistance rates (64.4%, 40.3%, and 29.1%, respectively). Moxifloxacin, vancomycin, imipenem, and gatifloxacin showed low percentages of resistance: 2.6%, 2.1%, 0.6%, and 0.4%, respectively. When comparing the results with previous studies in our institution, there was a decrease in sensitivity to the fourth-generation quinolones and imipenem, especially within the gram-negative ones. CONCLUSION: Fourth generation quinolones, imipenem and vancomycin continue to have a low in vitro resistance to bacteria that cause eye infections. However, there was a tendency to an increase in the resistance of gram-negative bacteria. Measures should be taken to try to control this phenomenon, and consider possible antimicrobial therapy alternatives to infections caused by these microorganisms.


Assuntos
Conjuntivite Bacteriana/tratamento farmacológico , Farmacorresistência Bacteriana , Endoftalmite/tratamento farmacológico , Ceratite/tratamento farmacológico , Antibacterianos/uso terapêutico , Colômbia , Conjuntivite Bacteriana/microbiologia , Estudos Transversais , Endoftalmite/microbiologia , Infecções por Bactérias Gram-Negativas/tratamento farmacológico , Infecções por Bactérias Gram-Positivas/tratamento farmacológico , Humanos , Ceratite/microbiologia , Testes de Sensibilidade Microbiana
3.
Infection ; 40(6): 689-94, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22527878

RESUMO

Dengue virus is the most significant virus transmitted by arthropods worldwide and may cause a potentially fatal systemic disease named dengue hemorrhagic fever. In this work, dengue virus serotype 4 was detected in the tissues of one fatal dengue hemorrhagic fever case using electron immunomicroscopy and molecular methods. This is the first report of dengue virus polypeptides findings by electron immunomicroscopy in human samples. In addition, not-previously-documented virus-like particles visualized in spleen, hepatic, brain, and pulmonary tissues from a dengue case are discussed.


Assuntos
Vírus da Dengue/genética , Vírus da Dengue/ultraestrutura , Dengue Grave/diagnóstico , Adulto , Anticorpos Antivirais/sangue , Encéfalo/ultraestrutura , Encéfalo/virologia , Cuba , DNA Viral/análise , Vírus da Dengue/isolamento & purificação , Ensaio de Imunoadsorção Enzimática , Evolução Fatal , Feminino , Coração/virologia , Humanos , Imunoglobulina M/sangue , Rim/ultraestrutura , Rim/virologia , Fígado/ultraestrutura , Fígado/virologia , Microscopia Eletrônica de Transmissão/métodos , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Dengue Grave/virologia , Baço/ultraestrutura , Baço/virologia
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