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1.
Head Neck Pathol ; 15(2): 663-667, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32865727

RESUMO

A patient with an odontogenic fibroma (OF) with the presence of fibroblasts of varying morphology is presented, and the main microscopic differential diagnosis is discussed. Case report: a 51-year-old man complained of a swelling in the anterior region of the mandible. The panoramic radiograph showed a radiolucent, well-defined multilocular image, with displacement of the roots of the left mandibular incisors and canine. A cone beam computed tomography examination revealed a hypodense image, with delicate bone spicules inside, divergence of the tooth roots and destruction of the buccal cortical bone. Under the differential diagnosis of a desmoplastic ameloblastoma or a squamous odontogenic tumor, an incisional biopsy was made. Microscopically, deeply collagenized tissue with scarce odontogenic epithelium islands, large fibroblasts of varying morphology and calcified material was observed. A diagnosis of OF was made. Surgical removal was carried out, and the specimen was examined. Identical aspects were found, and the immunohistochemical reaction for pan-cytokeratin was carried out to identify the odontogenic epithelial cells. The definitive diagnosis of OF was confirmed, and we emphasize the importance of the correlation of all characteristics for a definitive diagnosis.


Assuntos
Fibroblastos/patologia , Fibroma/patologia , Tumores Odontogênicos/patologia , Humanos , Masculino , Mandíbula/patologia , Pessoa de Meia-Idade
2.
J Clin Exp Dent ; 11(6): e582-e586, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31346382

RESUMO

Vascular leiomyomas (VL) are benign lesions of perivascular origin. We report two new cases and discuss their clinical, histological and immunohistochemical characteristics, in order to facilitate the diagnosis and treatment of such lesions. The patients, both male, presented asymptomatic nodules located in the bottom of the labial sulcus and buccal mucosa. In the second case, color doppler ultrasonography was performed, which showed no change in blood flow. After excisional biopsies, a limited lesion was observed histologically, with multiple tortuous vessels of varying sizes and calibers, and among them, spindle cells bundles, positive for smooth muscle actin. Oral VLs have clinical features similar to those of other more common lesions, making preoperative diagnosis difficult. Imaging examination, such as color doppler ultrasonography, may help in diagnosis. In general, excisional biopsy is performed, due to the ease of removal of the lesion during surgery. The treatment of choice is the complete excision of the lesion, which has an excellent prognosis and a low rate of recurrence. Key words:Vascular leiomyoma, spindle cells, thrombus, Doppler.

3.
Autops Case Rep ; 9(2): e2018073, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31321217

RESUMO

A mandibular buccal bifurcation cyst is an inflammatory cyst that usually occurs on the buccal aspect of the permanent mandibular first molar of children. This lesion is diagnosed by an association of radiographic, clinical, and histological features. We report a bilateral case of mandibular buccal bifurcation cyst and discuss the main findings of this entity. A 7-year-old girl presented pain and delayed dental eruption in the posterior mandibular region. A cone beam computed tomography was performed and revealed hypodense lesions involving the crown and root of the mandibular first molars, with expansion of the buccal cortical and lingual tilting of the molar roots. A biopsy was carried out, and the common features of an inflammatory odontogenic cyst were histologically observed. The final diagnosis was bilateral mandibular buccal bifurcation cyst. Clinicians need to be aware of this diagnostic possibility in cases of mandibular cysts in children-especially when bilateral-to perform the correct treatment, which should not involve the extraction of the affected tooth.

4.
Autops. Case Rep ; 9(2): e2018073, Abr.-Jun. 2019. ilus
Artigo em Inglês | LILACS | ID: biblio-999529

RESUMO

A mandibular buccal bifurcation cyst is an inflammatory cyst that usually occurs on the buccal aspect of the permanent mandibular first molar of children. This lesion is diagnosed by an association of radiographic, clinical, and histological features. We report a bilateral case of mandibular buccal bifurcation cyst and discuss the main findings of this entity. A 7-year-old girl presented pain and delayed dental eruption in the posterior mandibular region. A cone beam computed tomography was performed and revealed hypodense lesions involving the crown and root of the mandibular first molars, with expansion of the buccal cortical and lingual tilting of the molar roots. A biopsy was carried out, and the common features of an inflammatory odontogenic cyst were histologically observed. The final diagnosis was bilateral mandibular buccal bifurcation cyst. Clinicians need to be aware of this diagnostic possibility in cases of mandibular cysts in children­especially when bilateral­to perform the correct treatment, which should not involve the extraction of the affected tooth.


Assuntos
Humanos , Feminino , Criança , Doenças Mandibulares/patologia , Cistos Odontogênicos/diagnóstico por imagem , Cistos Maxilomandibulares , Cistos Odontogênicos/patologia
5.
Case Rep Pathol ; 2015: 805730, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26491592

RESUMO

Spindle cell lipoma is a benign lipomatous neoplasm, which rarely occurs in the oral cavity. The aims of this paper are to report a case of spindle cell lipoma located in buccal mucosa and discuss the main clinical, histological, and immunohistochemical findings of this entity. Thus, we report a 4-year history of an asymptomatic smooth surface nodule in an elderly Caucasian man with clinical hypothesis of fibroma. The histopathological examination showed spindle cells, mature adipose tissue, and many mast cells in a stroma of connective tissue presenting ropey collagen fibers bundles. After immunohistochemical analysis, the final diagnosis was spindle cell lipoma.

6.
Case Rep Pathol ; 2015: 507840, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26266070

RESUMO

Background. Calcified thrombi are a common finding, especially in the pelvic veins. There are generally multiple thrombi, and they are generally associated with vascular malformations. Design. Herein we report a rare case of a single labial phlebolith, not associated with any other vascular lesion. We aim to alert clinicians to the possibility of the occurrence of vascular thrombi in the mouth and to describe the clinical and histological characteristics of such lesions in order to simplify the diagnosis and treatment. Furthermore, we have reviewed the English-language literature published since 1970 reporting oral (including masticatory muscles) phleboliths. Results. Twenty-nine cases of phleboliths have been reported in the literature since 1970. Only three of the reported phleboliths were solitary and not associated with other vascular lesions, as in the case presented here. Conclusion. Although phleboliths not associated with other vascular lesions are not common, clinicians should be aware of the existence of this pathology and include it as differential diagnosis of oral lesions.

7.
Acta odontol. venez ; 48(3)2010. ilus
Artigo em Espanhol | LILACS | ID: lil-682909

RESUMO

La queilitis actínica es una lesión inflamatoria crónica del labio causada por la acción de los rayos solares. Debido a su lenta progresión, el paciente relaciona el proceso con una consecuencia del envejecimiento, ignorando su naturaleza evolutiva y cancerígena. El objetivo de este trabajo fue presentar el perfil clínico de los pacientes para realizar el diagnóstico. Fueron investigados 47 casos de queilitis actínica; la alteración de la línea de transición de la seni-mucosa de los labios con la piel se destacó por estar presente en 45 pacientes (96%). Concluimos que clínicamente todas las lesiones de queilitis actínica tenían aspecto multifocal; la presencia clínica de casi 100% de la alteración de la línea de transición de la seni-mucosa de los labios y la piel fue debida a la cronicidad de la afección; la resequedad labial fue disminuyendo porcentualmente por el hecho de realizar controles periódicos de los pacientes


Assuntos
Humanos , Masculino , Feminino , Boca/patologia , Medicina Clínica , Lábio/lesões , Queilite/diagnóstico , Odontologia
8.
J Med Case Rep ; 3: 98, 2009 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-19946515

RESUMO

INTRODUCTION: Ulcers are frequent lesions of the oral mucosa. Generally, they are circumscribed round or elliptical lesions surrounded by an erythematous halo and covered with an inflammatory exudate in their central portion, and are accompanied by painful symptoms. Oral ulcers affect 20% of the population, especially adolescents and young adults. The etiopathogenesis includes immunological alterations, infections, nutritional deficiency, trauma, food and contact allergies, autoimmune diseases, neoplasms, and psychosomatic, genetic and environmental factors. CASE PRESENTATION: A 78-year-old Caucasian woman was referred by her dentist to our outpatient clinic with a 4-week history of an oral ulceration after using an antidepressant (sertraline hydrochloride). On the basis of the clinical findings and anamnesis, the occurrence of the lesion was attributed to the use of the drug. Exfoliative cytology was performed, to reassure the patient that it was not oral cancer, which revealed the presence of a nonspecific inflammatory reaction. The drug was replaced and resolution of symptoms was observed. CONCLUSION: Exfoliative cytology should be the complementary examination of choice in cases of oral ulcers with a suspicion of drug interaction. Although this is a rare event in dental practice, dentists should be aware of the diagnostic possibility of drug-induced ulcers and should cooperate with the clinician to adjust the prescribed medication to resolve the symptoms.

9.
J Dent Child (Chic) ; 76(1): 78-81, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19341584

RESUMO

The purpose of this study was to report a case of bilateral swelling on the floor of the mouth of a 7-month-old patient. The lesion was congenital and had started to cause feeding problems. After the clinical diagnosis of ranula was made, the lesion was marsupialized. The obtained specimen was submitted for histopathological examination, which revealed an epithelial-lined cystic lesion. These results led to the final diagnosis of mucus retention cyst. After an 8-year follow-up period, the patient is in good general health with no recurrences.


Assuntos
Rânula/congênito , Humanos , Lactente , Soalho Bucal/patologia , Soalho Bucal/cirurgia , Rânula/cirurgia
10.
Med Oral Patol Oral Cir Bucal ; 13(10): E657-60, 2008 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-18830176

RESUMO

The purpose of this article was to describe the clinical and microscopic features of an intraosseous foreign-body granuloma in the mandible that developed after the traumatic implantation of metal fragments during a work-related accident. A 65-year-old male patient had a severe pain in the body of mandible. Clinical examination showed facial asymmetry and a scar, extending to the left mental region. Intraoral examination revealed a soft mass involving the left alveolar bone with normal appearance of the mucosa surface. Panoramic radiographs showed a radiolucent lesion along the mandible extending from the central incisive to the first molar. Computed tomography revealed an osteolytic mass in the same area. His medical history included a work-related accident twenty years prior to evaluation. During the biopsy an important amount of bright metal-like pieces surrounded by soft tissue were found. A microscopic examination showed a foreign body associated with an aggregation of multinucleated giant cells. The final diagnosis was a foreign body granuloma. Even though foreign-body granulomas in the mandible are rare lesions, dentists should be familiar with their features and include them in the differential diagnosis of tissue masses.


Assuntos
Acidentes de Trabalho , Granuloma de Corpo Estranho/diagnóstico , Granuloma de Corpo Estranho/etiologia , Doenças Mandibulares/diagnóstico , Doenças Mandibulares/etiologia , Traumatismos Mandibulares/complicações , Idoso , Humanos , Masculino , Fatores de Tempo
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