Assuntos

RESUMO

Context Gastrointestinal stromal tumors are uncommon abdominal neoplasms and can affect any portion of the gastrointestinal tract. Objectives Describe the tomographic findings of the gastrointestinal stromal tumor of gastric origin, correlating it with the mitotic index. Methods Twenty-one patients were selected within the period of January 2000 and 2008, with histopathological and immunohistochemical diagnosis of gastric gastrointestinal stromal tumors, who presented computed tomography done before the treatment. The tomographic variables analyzed were lesion topography, dimensions, contours, morphology, pattern and intensity enhancement through venous contrast, growth pattern, invasion of adjacent organs, presence of ulceration, fistula, calcifications, infiltration of mesenteric fat, lymphadenopathy and metastasis. The mitotic index was determined through optic microscopy, counting the number of mitosis figures in 50 high power fields. Results The tumors were located in the body (66.7%) or gastric fundus (33.3%), with dimensions varying between 4.2 and 21.2 cm (average of 10.5 cm). The growth was predominantly extraluminal (47.6%) or intra/extra luminal (28.6%). The enhancement by venous contrast was heterogeneous in 66.7%. The statistical analysis showed that irregular morphology (P = 0.027) and infiltration of mesenteric fat (P = 0.012) presented correlation with the high mitotic index. Conclusions In the present study, most part of the tumors were located in the gastric body, with average size of 10.5 cm, presenting central hypo dense area, heterogeneous enhancement through contrast and predominantly extra luminal growth. Irregular morphology and infiltration of mesenteric fat present statistical correlation with high mitotic level. .

Contexto Tumores estromais gastrointestinais são neoplasias raras e podem acometer qualquer segmento do trato gastrointestinal. A tomografia computadorizada é o método de imagem mais importante na detecção e caracterização do tumor. Objetivos Descrever os achados tomográficos do tumor estromal gastrointestinal de origem gástrica, correlacionando com o índice mitótico. Métodos No período de janeiro de 2000 a dezembro de 2008, foram selecionados 21 pacientes com diagnóstico histopatológico e imunohistoquímico de tumor estromal gastrointestinal, que apresentavam tomografia computadorizada realizada anteriormente ao tratamento. As variáveis tomográficas analisadas foram topografia da lesão, dimensões, contornos, morfologia, padrão e intensidade do realce pelo meio de contraste venoso, padrão de crescimento, invasão de órgãos adjacentes, presença de ulceração, fístula, calcificações, infiltração da gordura mesentérica, linfonodomegalias e metástases. O índice mitótico foi determinado através de microscopia óptica, com contagem do número de figuras de mitoses em 50 campos de grande aumento. Resultados Os tumores foram localizados no corpo (66,7%) ou fundo gástrico (33,3%), com dimensões variando entre 4,2 e 21,2 cm (média de 10,5 cm). O crescimento foi predominantemente extraluminal (47,6%) ou intra/extraluminal (28,6%). O realce pelo contraste venoso foi heterogêneo em 66.7%. A análise estatística mostrou que morfologia irregular (P = 0.027) e infiltração da gordura mesentérica (P = 0,012) apresentaram correlação com índice mitótico elevado. Conclusões No presente estudo, a maioria dos tumores localizava-se no corpo gástrico, com tamanho médio de 10.5 cm, ...

Assuntos

RESUMO

CONTEXT: Gastrointestinal stromal tumors are uncommon abdominal neoplasms and can affect any portion of the gastrointestinal tract. OBJECTIVES: Describe the tomographic findings of the gastrointestinal stromal tumor of gastric origin, correlating it with the mitotic index. METHODS: Twenty-one patients were selected within the period of January 2000 and 2008, with histopathological and immunohistochemical diagnosis of gastric gastrointestinal stromal tumors, who presented computed tomography done before the treatment. The tomographic variables analyzed were lesion topography, dimensions, contours, morphology, pattern and intensity enhancement through venous contrast, growth pattern, invasion of adjacent organs, presence of ulceration, fistula, calcifications, infiltration of mesenteric fat, lymphadenopathy and metastasis. The mitotic index was determined through optic microscopy, counting the number of mitosis figures in 50 high power fields. RESULTS: The tumors were located in the body (66.7%) or gastric fundus (33.3%), with dimensions varying between 4.2 and 21.2 cm (average of 10.5 cm). The growth was predominantly extraluminal (47.6%) or intra/extra luminal (28.6%). The enhancement by venous contrast was heterogeneous in 66.7%. The statistical analysis showed that irregular morphology (P = 0.027) and infiltration of mesenteric fat (P = 0.012) presented correlation with the high mitotic index. CONCLUSIONS: In the present study, most part of the tumors were located in the gastric body, with average size of 10.5 cm, presenting central hypo dense area, heterogeneous enhancement through contrast and predominantly extra luminal growth. Irregular morphology and infiltration of mesenteric fat present statistical correlation with high mitotic level.

Assuntos

Assuntos

RESUMO

OBJETIVO: Avaliar a adesão das funcionárias de um hospital em um programa de prevenção do câncer de mama por meio da mamografia. MATERIAIS E MÉTODOS: O estudo contou com 91 funcionárias analisadas por meio de questionário e acompanhamento da periodicidade da mamografia de 2000 até 2009. RESULTADOS: Foram realizadas 247 mamografias. Quarenta e oito funcionárias informaram obedecer à periodicidade do exame, e dessas, 12,6% realizaram o exame por solicitação médica, 47,9% por conhecerem a importância do exame, 4,1% por terem casos de câncer na família e 35,4% por rotina. Quarenta e três funcionárias não obedeceram à periodicidade do exame, sendo que 37,3% não fazem por não terem solicitação médica, 20,9% por não conseguirem pelo Sistema Único de Saúde, 18,6% por medo, 23,2% por não conhecerem a importância. CONCLUSÃO: A adesão ao programa foi baixa. As funcionárias desse hospital não têm conhecimento sobre a prevenção do câncer de mama.

OBJECTIVE: To evaluate the adherence of a hospital female personnel to a program for breast cancer prevention by means of mammography. MATERIALS AND METHODS: The study was developed with 91 female workers evaluated by means of a questionnaire and follow-up of the periodicity of mammographic studies in the period from 2000 to 2009. RESULTS: A total of 247 mammography studies were performed. Compliance with the periodicity schedule was informed by 48 of the participants, 12.6% of them by medical request, 47.9% because they were aware of the relevance of such study, 4.1% because of previous family history of cancer, and 35.4% as a clinical routine. Forty-three participants did not comply with the periodicity schedule, 37.3% of them because they had not a medical request, 20.9% because they could not have it done through the Sistema Único de Saúde (Brazilian Unified Health System), 18.6% for fear, and 23.2% due to unawareness about the relevance of such an examination. CONCLUSION: The participation in the program was low. The adherence to the program was poor in the hospital because of the unawareness about breast cancer prevention.

Assuntos

RESUMO

Os autores descrevem o caso de uma paciente jovem com amenorreia primária e caracteres sexuais secundários normais. A investigação diagnóstica constatou a ocorrência da síndrome de Mayer-Rokitansky-Kuster-Hauser.

The authors describe the case of a young female patient with primary amenorrhea and normal secondary sexual characteristics. The diagnostic investigation demonstrated the occurrence of Mayer-Rokitansky-Kuster-Hauser's syndrome.

Assuntos

RESUMO

UNLABELLED: Perform a comparative analysis (with the criteria of Ahlbäck original classification) of the anteroposterior (AP) weight-bearing radiograph of knee in extension and of Rosenberg(2) view, in symptomatic arthritic knees. The analysis aims at revealing agreement or disagreement between (AP) view and Rosenberg view and the degree of articular degeneration and the advantages of these views. PATIENTS AND METHODS: From January 2005 to March 2007, a prospective study was conducted with 76 selected patients (111 arthritic knees) attending the outpatient clinic, at the knee unit, and subjected to the radiographs proposed in the present study. Of the total number of patients (76), 52 were females and 24 males, having an average age of 62 (range, 50- 82 years). 41 patients had unilateral degeneration and 35 patients had bilateral degeneration. Of the total number of assessed knees (111), 66 were right knees and 45 were left knees. The study used the Kappa statistical analysis, which assesses interobserver agreement of qualitative data. RESULTS: According to the Ahlbäck score, there was agreement between the orthopedist and the radiologist in 98.2% of cases in the AP weight-bearing view, and in 88.3% in the Rosenberg view. A highly significant agreement on both views between the orthopedist and the radiologist was noticed. However, the degree of agreement was higher for the AP weigh-bearing view than for the Rosenberg view. According to the Ahlbäck score, the AP weight-bearing view agreed with the Rosenberg view in only 27% of the cases for the orthopaedist, and in 31.5% for the radiologist. No significant agreement was found between the AP weight-bearing view and the Rosenberg view for the orthopedist and the radiologist. CONCLUSIONS: There is no significant disagreement between experts concerning the classification of knee osteoarthritis, according to the Ahlbäck score, both for the AP weight-bearing view and the Rosenberg view. There is no agreement between the views, concerning the classification of knee osteoarthritis, both for the orthopedist and the radiologist, the Rosenberg view having shown more clearly the degree of articular degeneration. The posteroanterior view of Rosenberg provided a better assessment of degeneration of the articular surface, which in some cases led to a change in the classification of knee osteoarthritis and was routinely used.

Assuntos