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PURPOSE: To critically evaluate the evidence on knowledge changes observed after the application of evidence-based dentistry (EBD) educational interventions to dental students. METHODS: We included studies that assessed EBD knowledge after applying educational interventions to undergraduates. Studies that evaluated post-graduate students or professionals, that exclusively described educational interventions, programs, or the application of curriculum revisions were excluded. Electronic databases (PubMed, Embase, Scopus, and Web of Science), unpublished gray literature, and manual searches were performed. Data concerning "perceived" and "actual knowledge" was extracted. The quality of the studies was appraised according to the Mixed Methods Appraisal Tool. RESULTS: The 21 selected studies enrolled students at different stages, and the intervention formats were diverse. The educational interventions could be categorized into three modalities, that is, regular, EBD-focused disciplines or courses, and other educational interventions including one or more of the EBD principles, methods, and/or practices. Despite the format, knowledge was generally improved after the implementation of educational interventions. Overall, perceived and actual levels of knowledge increased considering EBD general concepts, principles, and/or practices, and concerning the "acquire" and "appraise" skills. Among the selected studies, two were randomized controlled trials, while most were non-randomized or descriptive studies. CONCLUSIONS: EBD-related educational interventions seem to improve dental students' perceived and actual knowledge, according to literature with a high risk of bias. Therefore, more complete, methodologically rigorous, and longer-term studies are still recommended to confirm and expand the current knowledge.

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Introdução: Osteonecrose dos Maxilares Associada ao Uso de Medicamentos (OMAM) foi diagnosticada pela primeira vez em 2003. É caracterizada pela presença de osso necrosado exposto na região maxilofacial com persistência de mais de oito semanas em pacientes que não tenham história de radioterapia em cabeça e pescoço e que tenham feito uso prévio ou atual de bisfosfonatos ou terapias antiangiogênicas. Tem significativa morbidade, afetando negativamente a qualidade de vida de seu portador, pois pode haver dor, exposição óssea, edema, infecção, parestesia, halitose, mobilidade dentária e secreção purulenta. Como não há ainda uma etiologia totalmente definida, não existe um padrão ouro de protocolo para seu tratamento. Desta forma, a terapia fotodinâmica (PDT) surge como um tratamento alternativo devido ao seu efeito antimicrobiano. Objetivo: trata-se uma revisão de literatura acerca do uso da PDT como tratamento auxiliar ou coadjuvante da OMAM. Método: Para tal, foi realizada uma busca de artigos científicos publicados entre 2014 e 2018 em língua inglesa e portuguesa, disponíveis nas bases de dados Medical Publications e Scientific Eletronic Library Online. Conclusão: verificou-se que, apesar de não se ter clareza acerca de um protocolo definido para tratamento da OMAM, a PDT tem se mostrado como uma terapia promissora, na medida em que tem levado a reiterados sucessos no auxílio para a cura desta enfermidade.

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) was first diagnosed in 2003. It is characterized by the presence of exposed necrotic bone in the maxillofacial region with persistence of more than eight weeks in patients with no history of head and neck radiotherapy and that have made prior or current use of bisphosphonates or antiangiogenic therapies. It has significant morbidity, negatively affecting the quality of life of its bearer, since there may be pain, bone exposure, edema, infection, paresthesia, halitosis, dental mobility and purulent secretion. As there is not yet a fully defined etiology, there is no gold standard protocol for its treatment. Thus, photodynamic therapy (PDT) emerges as an alternative treatment due to its antimicrobial effect. Objective: The aim of this study was a literature review about the use of PDT as an auxiliary or co-adjutant treatment of MRONJ. Method: It was made a search of scientific papers published between 2014 and 2018, in English and in Portuguese, available in Medical Publications and Scientific Electronic Library Online databases. Conclusion: In this way, although a define protocol for treatment of MRONJ is not clear yet, it was verified that the PDT has shown as a promising therapy as far as it has led to repeated successes in the aid for the cure o this disease.

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