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Pediatr Phys Ther ; 30(3): 209-215, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29924070

RESUMO

PURPOSE: To quantitatively describe passive lower extremity range of motion in participants with spinal muscular atrophy (SMA) types 2 and 3, and to establish preliminary thresholds to identify individuals at risk for performing poorly on disease-specific motor function outcome measures. METHODS: Eighty participants with SMA types 2 and 3, enrolled in an international multicenter natural history study, were evaluated with lower extremity range of motion testing and the Hammersmith Functional Motor Scale-Expanded. RESULTS: A hip extension joint angle of -7.5° or less for SMA type 2 and 0° or less for SMA type 3 identified diminished motor ability with good sensitivity. For knee extension, a joint angle of -9.0° or less for SMA type 2 or 0° or less for SMA type 3 was similarly sensitive. CONCLUSIONS: Minimal hip and knee joint contractures were associated with diminished motor ability. Clinical trial designs should consider the effect of contractures on motor function.


Assuntos
Contratura/fisiopatologia , Articulação do Quadril/fisiopatologia , Articulação do Joelho/fisiopatologia , Extremidade Inferior/fisiopatologia , Transtornos Motores/fisiopatologia , Atrofia Muscular Espinal/fisiopatologia , Amplitude de Movimento Articular/fisiologia , Adulto , Feminino , Humanos , Masculino
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