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Transplant Proc ; 50(3): 746-749, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29661428

RESUMO

BACKGROUND: The incidence of anemia in kidney transplantation patients (KTPs) is very common and seems to be associated with the reduction in both renal function and physical exercise tolerance. The purpose of the present study was to compare biochemical markers of anemia and renal function of physically active and sedentary KTPs. METHOD: Serum hemoglobin (Hb), hematocrit (Hct), and serum creatinine (used to derive estimated glomerular filtration rate [eGFR]) were obtained from the medical records of 18 KTPs assisted at the Center for Prevention of Kidney Diseases of the Federal University of Maranhao Hospital. The physically active transplant patients (group 1) included 7 men and 2 women, aged 49 ± 14 years who participated for at least 6 months on a supervised physical exercise program (SPEP) (2 to 3 times a week, 90-minute sessions) and the sedentary counterparts (group 2) of 2 men and 7 women, aged 37 ± 15 years. RESULTS: Group 1 presented higher values of Hb (14.2 ± 2.6 vs 10.7 ± 0.6 g/dL; P = .003), Hct (41.6% ± 7.0% vs 32.3% ± 1.4%; P = .004), and eGFR (64.4 ± 19.4 vs 39.3 ± 19.7 mL/min/1.73 m2; P = .015) when compared with group 2. There was a positive and significant correlation between Hb and eGFR (r = 0.528; P = .024), and between Hct and eGFR (r = .509; P = .031). CONCLUSIONS: Our results suggest that regular physical activity seems to improve the biochemical markers of anemia and also the renal function of KTPs, and these patients should be advised to participate in SPEP.


Assuntos
Anemia/etiologia , Exercício Físico/fisiologia , Nefropatias/fisiopatologia , Transplante de Rim/efeitos adversos , Complicações Pós-Operatórias/etiologia , Adulto , Biomarcadores/análise , Creatinina/sangue , Tolerância ao Exercício/fisiologia , Feminino , Taxa de Filtração Glomerular , Hematócrito , Hemoglobinas/análise , Humanos , Nefropatias/sangue , Nefropatias/cirurgia , Testes de Função Renal , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Comportamento Sedentário , Adulto Jovem
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