RESUMO

The production of polymeric complexes in many active drugs with reticulated povidone increased dissolved component percentage. In this work made use a coevaporation technique. Complex formation has been tested by X Ray Diffractometry and Differential Scanning Calorimetry. The percentage of dissolution was determined to the USP XXIII Edition methodology. As can be seen from the results, the Atenolol-reticulated Povidone complexes has greater solubility than the Atenolol mixed with Lactose as excipient.

Assuntos

Antagonistas Adrenérgicos beta/química , Atenolol/química , Povidona/química , Antagonistas Adrenérgicos beta/administração & dosagem , Atenolol/administração & dosagem , Varredura Diferencial de Calorimetria , Composição de Medicamentos , Excipientes Farmacêuticos , Solubilidade , Difração de Raios X