RESUMO

The history of the previous and the later Papanicolaou smears results with diagnosis of atypical squamous cells (ASC) and its correlation with respective biopsies was retrospectively analyzed. The previous and the later exams which resulted as diagnoses of ASC by cytologic test were investigated, and also the examinations periodicity. Of 60 selected cases of ASC with correlated biopsy results, 57 had the first cytologic diagnosis of ASC-US (undetermined significance) and 3 had ASC-H (cannot exclude high grade lesion) diagnosis. Of 57 cases, 30 (52.6%) were negative on biopsy, 16 (28.1%) had a diagnosis of NIC 1, and 11 (19.3%) presented diagnose discrepancies above 2 degrees. Among ASC-H (100%) all the cases were diagnosed as NIC 1 on biopsy. Of 60 cases, 44 (73.3%) cases who had previous examinations results, 14 (23.3%) were positive. Among patients who had the later cytology exams, 53 (88.3%) had cytologic examinations after being biopsied, and 10 (16.7%) were positive. Concerning the examinations periodicity, 26 (43.3%) were examined 1- year interval, 29(48.3%) at 1 to 3-year interval, and one (1.7%) at a period longer than three years. According to the observed findings the ASC diagnoses were frequently associated with reactional morphologic changes, showing the relevance in carrying out the cyto-histological correlation, since performing cytological follow up only it shoul

No presente estudo foi avaliada a história de realização dos exames citológicos (EC) prévios e posteriores com diagnóstico citológico de células escamosas atípicas (ASC) e sua correlação com os resultados de exames de biópsias. Para tanto, foi realizado o estudo retrospectivo, de 60 casos de EC cérvico-vaginais com diagnóstico de ASC e biópsias correlatas, os exames prévios e posteriores de ASC e a periodicidade de exames realizados. Das 60 análises selecionadas, 57 apresentaram diagnóstico citológico anterior de ASC-US (possivelmente não neoplásico), 30 (52,6%) foram negativos no exame de biópsia, 16 (28,1%) de NIC 1, 11 (19,3%) com diagnósticos discrepantes acima de 2 graus; 3 (100%) casos de ASC-H(não se pode afastar lesão de alto grau) foram NIC 1 na biópsia. Dentre os 60 casos, 44 (73,3%) que tiveram exames anteriores, 14 (23,3%) eram positivos; 53 (88,3%) que fizeram EC posteriores à biópsia, 10 (16,7%) eram positivos. Quanto à periodicidade dos exames, 26 (43,3%) realizaram o exame com intervalo de até 1 ano, 29 (48,3%) de 1 a 3 anos, 1 (1,7%) em intervalo maior que 3 anos. De acordo com os achados observados neste estudo, os diagnósticos citológicos de ASC, quando comparado com os exames da biópsia, estavam mais frequentemente associados às alterações morfológicas reacionais. Estes dados mostram o valioso papel da correlação cito-histológica, uma vez que a execução apen