RESUMO
The aim of this study was to evaluate the histopathological changes to the mammary gland that occur in female dogs with visceral leishmaniosis and to correlate the findings with the parasite load, inflammatory cell profile in mammary tissue and serum progesterone levels. For this, 20 adult female dogs that were naturally infected with Leishmania infantum, not spayed, not pregnant and free from mammary tumors were used. They were divided into two groups: G1 (n = 9) with high serum progesterone levels and G2 (n = 11) with low serum progesterone levels. The parasite load and the immunophenotype of leukocytes infiltrated into the mammary tissue (CD3, CD4, CD8 and MCA874) were evaluated using the immunohistochemical technique. In the mammary gland, chronic inflammatory infiltrate was mainly found in G1, sometimes associated with granulomatous inflammation, higher parasite load and higher density of cells immunolabeled for CD3, CD4, CD8 and MCA874. A significant positive correlation (p < 0.05) was observed between the parasite load and the immunolabeled leukocytes. The influence of the serum progesterone level in the mammary gland of infected female dogs can contribute to the maintenance of an immunosuppressive cell profile and favor the persistence of the parasite in this site.
Assuntos
Doenças do Cão , Leishmania infantum , Leishmaniose Visceral , Animais , Cães , Feminino , Leishmaniose Visceral/veterinária , Carga Parasitária/veterinária , Gravidez , ProgesteronaRESUMO
A obstrução uretral em felinos é uma etiologia comum e rotineira para clínicos e cirurgiões. A afecção pode ocorrer por vários motivos, mas de maneira geral, leva a sérios distúrbios renais e hidroeletrolí-ticos, que quando não revertidos rapidamente causarão o óbito do paciente. Este trabalho traz uma opção de abordagem de pacientes felinos com obstrução da uretra, bem como opções para tratamento emergencial e desobstrução.
Urethral obstruction in felines is a common and routine etiology for clinicians and surgeons. The condition can occur for several reasons, but in general leads to serious renal and hydroelectrolytic disorders, that when not quickly reversed caused the death of the patient. This article brings an option to approach these feline patients with urethral obstruction, as well as options for emergency treatment and urethral clearance.
Assuntos
Animais , Gatos , Obstrução Uretral/veterinária , Protocolos Clínicos/normas , Gatos/anormalidadesRESUMO
A obstrução uretral em felinos é uma etiologia comum e rotineira para clínicos e cirurgiões. A afecção pode ocorrer por vários motivos, mas de maneira geral, leva a sérios distúrbios renais e hidroeletrolí-ticos, que quando não revertidos rapidamente causarão o óbito do paciente. Este trabalho traz uma opção de abordagem de pacientes felinos com obstrução da uretra, bem como opções para tratamento emergencial e desobstrução.(AU)
Urethral obstruction in felines is a common and routine etiology for clinicians and surgeons. The condition can occur for several reasons, but in general leads to serious renal and hydroelectrolytic disorders, that when not quickly reversed caused the death of the patient. This article brings an option to approach these feline patients with urethral obstruction, as well as options for emergency treatment and urethral clearance.(AU)