RESUMO
Atypical fibroxanthoma is an uncommon mesenchymal tumor that manifests clinically as a reddish papule or nodule in sun-exposed areas of the body. The clinical presentation is not specific and histology and immunohistochemistry are both necessary for a correct diagnosis. Surgery is the gold standard of therapy. Recurrence and metastasis should be excluded with a follow-up at 6 months, since this tumor should nowadays be considered a medium-grade neoplasm, rather than low-grade as previously believed. We report the case of two friends who came to our hospital during the same period, complaining of very similar lesions. After biopsy and immunohistochemical examination, a diagnosis of atypical fibroxanthoma in both cases was formulated.
Assuntos
Pavilhão Auricular/patologia , Neoplasias da Orelha/patologia , Fibroma/patologia , Neoplasias Cutâneas/patologia , Xantomatose/patologia , Idoso , Biópsia , Diagnóstico Diferencial , Amigos , Humanos , Imuno-Histoquímica , MasculinoRESUMO
We present the rare case of a 47-year-old patient, suffering from cheilitis granulomatosa and lupus erythematosus discoid: this association is really exceptional because only once reported in English literature. In addition, the treatment of cheilitis granulomatosa is a challenge for the dermatologist: the gold standard, represented by steroids, is in fact designed as a short-time option. Our report confirms the good efficacy of methotrexate as a steroid-sparing agent.
Assuntos
Fármacos Dermatológicos/uso terapêutico , Lúpus Eritematoso Discoide/tratamento farmacológico , Síndrome de Melkersson-Rosenthal/tratamento farmacológico , Metotrexato/uso terapêutico , Biópsia , Derme/patologia , Humanos , Lábio/patologia , Lúpus Eritematoso Discoide/patologia , Masculino , Síndrome de Melkersson-Rosenthal/patologia , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
Tufted angioma is a rare vascular tumor whose name derives from its histopathological appearance, characterized by tufts of capillaries within the dermis. Its etiology and pathogenesis are uncertain. Tufted angioma typically occurs during infancy or early childhood and displays various clinical patterns. It may present as a subtle stain-like area that later thickens as a large plaque, infiltrated or dusky blue-purple lesion, or as an exophytic, firm, violaceous, cutaneous nodule. Medical treatment is not necessary for tufted angioma, given its benign nature and slow progression. Only clinical follow-up is therefore recommended.
Assuntos
Hemangioma/patologia , Neoplasias Cutâneas/patologia , Neoplasias Vasculares/patologia , Idade de Início , Derme/patologia , Feminino , Humanos , Imuno-Histoquímica , Pessoa de Meia-Idade , OmbroRESUMO
AbstractAtypical fibroxanthoma is an uncommon mesenchymal tumor that manifests clinically as a reddish papule or nodule in sun-exposed areas of the body. The clinical presentation is not specific and histology and immunohistochemistry are both necessary for a correct diagnosis. Surgery is the gold standard of therapy. Recurrence and metastasis should be excluded with a follow-up at 6 months, since this tumor should nowadays be considered a medium-grade neoplasm, rather than low-grade as previously believed. We report the case of two friends who came to our hospital during the same period, complaining of very similar lesions. After biopsy and immunohistochemical examination, a diagnosis of atypical fibroxanthoma in both cases was formulated.
Assuntos
Idoso , Humanos , Masculino , Pavilhão Auricular/patologia , Neoplasias da Orelha/patologia , Fibroma/patologia , Neoplasias Cutâneas/patologia , Xantomatose/patologia , Biópsia , Diagnóstico Diferencial , Amigos , Imuno-HistoquímicaRESUMO
We present the rare case of a 47-year-old patient, suffering from cheilitis granulomatosa and lupus erythematosus discoid: this association is really exceptional because only once reported in English literature. In addition, the treatment of cheilitis granulomatosa is a challenge for the dermatologist: the gold standard, represented by steroids, is in fact designed as a short-time option. Our report confi rms the good efficacy of methotrexate as a steroid-sparing agent.
.Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Fármacos Dermatológicos/uso terapêutico , Lúpus Eritematoso Discoide/tratamento farmacológico , Síndrome de Melkersson-Rosenthal/tratamento farmacológico , Metotrexato/uso terapêutico , Biópsia , Derme/patologia , Lábio/patologia , Lúpus Eritematoso Discoide/patologia , Síndrome de Melkersson-Rosenthal/patologia , Resultado do TratamentoRESUMO
Tufted angioma is a rare vascular tumor whose name derives from its histopathological appearance, characterized by tufts of capillaries within the dermis. Its etiology and pathogenesis are uncertain. Tufted angioma typically occurs during infancy or early childhood and displays various clinical patterns. It may present as a subtle stain-like area that later thickens as a large plaque, infi ltrated or dusky blue-purple lesion, or as an exophytic, fi rm, violaceous, cutaneous nodule. Medical treatment is not necessary for tufted angioma, given its benign nature and slow progression. Only clinical follow-up is therefore recommended.
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