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Background: The pandemic propagation of SARS-CoV-2 led to the adoption of a myriad of non-pharmacological interventions (NPIs, e.g., social distancing, mobility restrictions, gathering restrictions) in the Americas. Using national epidemiological data, here we report the impact of the layered adoption of multiple NPIs aimed at curving SARS-CoV-2 transmission in Yucatan State, Mexico. Methods: Data from suspected and laboratory confirmed COVID-19 cases during 2020 were analyzed by age groups and sex, clinical signs, and symptoms as well as outcome. The impact of NPIs was quantified using time-varying reproduction numbers (R t) estimated as a time-series and by sectors of the city. Findings: A total of 69,602 suspected cases were reported, 39.3% were laboratory-confirmed. Men were hospitalized (60.2%), more severely ill (3% vs 1.9%) and more likely to die (62%) than women. Early in the outbreak, all sectors in Merida had R t estimates above unity. Once all NPÍs were in place, R t values were dramatically reduced below one, and in the last interval transmission estimates of R t remained below one in all sectors. Interpretation: In the absence of a COVID-19 vaccination program, the combination and wide adherence of NPÍs led to a low and stable trend in SARS-CoV-2 transmission that did not overwhelm the health sector. Our study reflects that a controlled and planned ease of restrictions to balance health, social and economic recovery resulted in a single wave of transmission that prolonged at low and stable levels. Funding: GVP received funding from Emory University via the MP3 Initiative.

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We evaluated the impact of weather variables and climatic indicators associated with the incidence of dengue in two municipalities of the state of Veracruz, Mexico, from 1995 to 2003. A retrospective ecological study was conducted, using time-series analysis in which we compiled the weekly reported cases of dengue and the weather and climatic parameters: temperature, rainfall and sea-surface temperature (SST), the latter as an El Niño Southern Oscillation indicator. We statistically evaluated the data with autogressive models. The models' predictive abilities were evaluated using data collected from 1995 to 2002 and were validated with those observed for 2003. Each degree Centigrade increase in SST was followed by an increase in the number of dengue cases: 46% in San Andrés Tuxtla (P = 0.001) 16 weeks later and 42% in Veracruz 20 weeks later (P = 0.002). Increases in weekly minimum temperature and rainfall were also significant factors in the increase in the reported cases of dengue. We recommend future studies using the same method, involving larger populations with different geographic location, climate and weather. We also recommend strengthening environmental, health and entomological surveillance systems to improve preparedness and emergency responses.

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The Mexican Ministry of Health's anti-malaria campaigns of the last sixty years have overlapped and interacted with both the World Health Organization's Global Eradication Program and a series of major political, social, and demographic movements in Mexico, including economic transformation, migration, urbanization, tourism, rural development, and the building of social and sanitary services. The authors argue that three decades of successful environmentally-oriented malaria work that integrated social and economic development was followed by the Global Campaign's insecticide-based approach that failed in both its economic and public health objectives, ultimately serving to block development efforts, particularly in poorer and southern states.

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Field trials of the predacious copepod Mesocyclops longisetus Thiubaud were conducted in northeastern Mexico to determine the effectiveness of this species to control larval Aedes aegypti (L.) populations and to survive and reproduce in nature. Groups of 200, 50, and 50 ovigerous M. longisetus females were inoculated into 200-liter metal drums, discarded tires, and cemetery flower vases, respectively, which are 3 of the more important Aedes breeding sites in this area. Larvae were sampled at 15-d intervals, and total surviving cyclops were collected at the end of the study, 120 d later. Community participation was solicited through a simple training program on copepod rescue before drum cleaning and facilitated by the addition of a drum marker to remind residents of copepod presence. Results showed good cooperation and after 4 mo all peridomestic drums, still supported variable numbers of cyclopoids. Average of larvae reduction was 37.5% for drums, 67.5% for flower vases, and 40.9% for tires. This study shows difficulties of using cyclopoids for tires and vases in areas where prolonged dry seasons desiccated these habitats and reduced copepod survival.

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OBJECTIVE: To describe the sociodemographic characteristics and determinants of health services utilization by the Mexican population of 60 years of age or more. MATERIAL AND METHODS: Information obtained from the National Health Survey II (ENSA-II) allowed analysis of 4,628 elderly people. Prevalence of chronic diseases was analyzed and the determinants of individuals who had used the health services in the two weeks prior to the interview. RESULTS: The chronic diseases most frequently reported were: hypertension, diabetes and heart disease. The utilization and hospitalization rates of that age group were 11.4 and 5.5%, respectively. The services most frequently used were: the private physician, social security (IMSS, ISSSTE) welfare services (Ministry of Health--SSA- and IMSS-Solidaridad). Interestingly, 25 to 45% of social security insurance holders did not use the services, instead they consulted a private physician. The most important explanatory variables for health services utilization were: the perceived illness, not having worked for the previous week and being a social security insurance holder. Gender, area of residence and level of education were not significant in the explanation of health services utilization. CONCLUSIONS: This study demonstrates the need to strengthen preventive and support programs for the elderly population, since they only demand health services when they feel sick.

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Public Health has evolved in accordance with basic scientific and technologic advances. Molecular biology has provided sophisticated laboratory techniques and fine diagnostic tools that are being exploited in the area of Public Health in order to deepen our knowledge of the natural history of diseases, identify populations at risk, diagnose infectious process and different pathologies in the early stages of the illness and limit the damage produced by a late diagnosis. The modern molecular techniques provide a promising insight into the identification and measurement of molecular structures linked to the pathological process, the genotypic identification of infectious agents, the level of exposure and the susceptibility at individual as well as population levels. This paper describes its applications in the area of Public Health and highlights its limits and potential risks.

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OBJECTIVE: The results of the National Survey of Chronic Diseases (Mexico, 1993) regarding the prevalence of hypertension, diabetes mellitus and obesity in the 60 to 69 years old group are presented on a national and regional level. MATERIAL AND METHODS: Measurements taken included weight, height, blood pressure, visual acuity, glycosylated hemoglobin, cholesterol, lipoproteins, insulin, triglycerides and albumin. Data analysis were performed using the statistical package SPSS to carry out Mantel-Haenszel and chi square tests. RESULTS: Analysis of data for 1239 individuals showed that 38% of the aging population have hypertension. 25% are obese and 21% have diabetes. Findings showed that 28% of the individuals with hypertension and 18% of those with diabetes were detected through the survey. Obesity was strongly associated with hypertension and 33% of cases were not under treatment. Differences on the regional level are presented and results are discussed by sex and risk factors. The risk of diabetes was higher in those with other family members with diabetes, while microalbuminuria and hypercholesterolemia were associated with diabetes in this population. CONCLUSIONS: The results of the study support the need to improve early detection programs and intensify those interventions that prevent early mortality due to these particular diseases.

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OBJECTIVE: The purpose of this study was to determine the characteristics of hospital utilization by the elderly in three hospitals in Mexico City during 1992 and 1993. Main reason for admission, average length of stay and type of treatment received were some of the variables studied. MATERIAL AND METHODS: A random sample of 820 clinical files were selected, 308 from the Instituto Nacional de la Nutrición Salvador Zubirán (INNSZ), 189 from the Hospital General Manuel Gea González (HGMGG) and 323 from the Hospital Regional Adolfo López Mateos (HRALM). The principal reasons for admission, average days spent in the hospital and type of treatment received were identified for patients 60 years and older. Univariate and bivariate analysis was performed with hypothesis test for differences between sexes. RESULTS: Diabetes mellitus and hypertension were the principal reasons for admission length of stay varied considerably and was the longest at the INNSZ (median: 12 days) and the shortest at the HRALM (median: 8 days). Most of the patients were admitted through the emergency service, except in the INNSZ where most came for ambulatory visit.

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