Assuntos
Adenocarcinoma/tratamento farmacológico , Anafilaxia/prevenção & controle , Anticorpos Monoclonais Humanizados/uso terapêutico , Antineoplásicos Imunológicos/uso terapêutico , Bevacizumab/uso terapêutico , Dessensibilização Imunológica/métodos , Hipersensibilidade a Drogas/terapia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/prevenção & controle , Neoplasias Pulmonares/tratamento farmacológico , Adenocarcinoma/complicações , Anafilaxia/etiologia , Anticorpos Monoclonais Humanizados/efeitos adversos , Antineoplásicos Imunológicos/efeitos adversos , Bevacizumab/efeitos adversos , Hipersensibilidade a Drogas/complicações , Humanos , Neoplasias Pulmonares/complicações , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Resultado do TratamentoAssuntos
Anafilaxia/etiologia , Anafilaxia/terapia , Antineoplásicos Imunológicos/efeitos adversos , Neoplasias da Mama/complicações , Dessensibilização Imunológica , Trastuzumab/efeitos adversos , Anafilaxia/diagnóstico , Antineoplásicos Imunológicos/uso terapêutico , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/tratamento farmacológico , Dessensibilização Imunológica/métodos , Hipersensibilidade a Drogas/diagnóstico , Hipersensibilidade a Drogas/etiologia , Hipersensibilidade a Drogas/terapia , Feminino , Humanos , Pessoa de Meia-Idade , Terapia de Alvo Molecular/efeitos adversos , Estadiamento de Neoplasias , Testes Cutâneos , Avaliação de Sintomas , Trastuzumab/uso terapêuticoRESUMO
There are not enough data concerning asthma mortality in Latin America. The Latin American Society of Allergy and Immunology coordinated this project to provide reliable data for gaining knowledge about our present situation, which is a condition indispensable to changing it. The following countries participated in this study: Argentina, Brazil, Chile, Colombia, Costa Rica, Cuba, Mexico, Paraguay, Peru, Uruguay and Venezuela. A uniform protocol was designed in Santa Fe, Argentina. Asthma mortality rates were analyzed in accordance with two variables: age-adjusted rates (5-34) and total death rates. The total population studied was 107, 122, 529 inhabitants. The highest death rates were found in Uruguay and Mexico (5.63), and the lowest in Paraguay (0.8) and Colombia (1.35). Age-adjusted (5-34) rates were higher in Costa Rica (1.38) and lower in Chile (0.28). Regarding sex, the analysis of the information provided by seven countries showed a predominance of females (51.8%) over males (48.18%). In the southern Latin American countries such as Chile, Uruguay, Paraguay and Argentina, which have marked climatic differences, deaths occurred mainly in the winter. It is important to emphasize that, in most countries, deaths from asthma occurred at home: Chile (60.7%), Argentina (63.4%) and Paraguay (88%). However, in Uruguay, 58.6% occurred during hospitalization. Mortality rates from bronchial asthma are high in most of the Latin American countries studied, even though further studies are needed. Asthma is a serious global health problem. People of all ages in countries throughout the world are affected by this chronic airway disorder that can be severe and sometimes fatal. The health ministries of each country do not believe asthma is a significant issue. Therefore, we should provide them with sound epidemiological studies to convince them to change their attitude toward this disease.
Assuntos
Asma/mortalidade , Adolescente , Adulto , Fatores Etários , Idoso , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , América Latina/epidemiologia , Masculino , Pessoa de Meia-Idade , Fatores SexuaisRESUMO
The inflammatory response in the upper airways secondary to viral or bacterial infection is frequent cause of medical attention and rhinosinusitis a common complication, changes in local and systemic immunity could facilitate the presence of sinusitis. Mediators derived from eosinophil could be also an important factor to develop nasal inflammation.
Assuntos
Rinite/fisiopatologia , Ribonucleases , Sinusite/fisiopatologia , Proteínas Sanguíneas/análise , Doença Crônica , Proteínas Granulares de Eosinófilos , Eosinofilia/fisiopatologia , Humanos , Mucosa Nasal/imunologia , Seios Paranasais/fisiopatologia , Infecções Respiratórias/complicações , Infecções Respiratórias/imunologia , Rinite/etiologia , Rinite/imunologia , Rinite Alérgica Perene/imunologia , Rinite Alérgica Perene/fisiopatologia , Sinusite/etiologia , Sinusite/imunologiaRESUMO
Chronic rhinosinusitis occurs to 5% of the population with upper respiratory infections. The objective of this study is to know the main symptoms in a pediatric population younger than 14 years with the diagnosis of chronic rhinosinusitis, to know age and sex distribution and evolution. We did a medical history, physical examination, nasal cytology, skin tests and sinus X rays in each of 100 patients. Results the main symptoms were: cough, halitosis, postnasal discharge, fever, headache, sore throat, facial sensitivity and periorbital edema. This findings predominated in males and the average evolution time was 1-2 years.
Assuntos
Rinite/diagnóstico , Sinusite/diagnóstico , Adolescente , Asma/epidemiologia , Criança , Pré-Escolar , Doença Crônica , Comorbidade , Feminino , Humanos , Lactente , Masculino , México/epidemiologia , Seios Paranasais/diagnóstico por imagem , Exame Físico , Estudos Prospectivos , Radiografia , Infecções Respiratórias/epidemiologia , Rinite/epidemiologia , Rinite Alérgica Perene/epidemiologia , Sinusite/epidemiologiaRESUMO
UNLABELLED: The rhinosinusitis es becoming a more common diagnosis in the practice of the allergist, in this retrospective langencial study of one year (1993) we found this disease occurred in the 42% of the total consultation demanding our service. There was not difference by sex, and by age were more prevalent under 15 years (57%). ETIOLOGY: the allergic represented 57% of patients infectious in 25% and both in 18%. Mites were the most frequent antigen found positive buy skin test.
Assuntos
Rinite/epidemiologia , Sinusite/epidemiologia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Rinite Alérgica Perene/epidemiologiaRESUMO
At Mexico City General Hospital, a 32-year-old female with autoimmune hemolytic anemia associated with cholelithiasis underwent elective laparoscopic cholecystectomy and splenectomy. The gallbladder and the spleen were delivered intact through a 7-cm extension of the umbilical trocar site. The patient was discharged in excellent condition. We describe the technique of laparoscopic splenectomy and suggest new advantages for the laparoscopic approach to surgery of the spleen.
Assuntos
Laparoscopia/métodos , Esplenectomia/métodos , Adulto , Anemia Hemolítica Autoimune/terapia , Colecistectomia Laparoscópica , Colelitíase/cirurgia , Feminino , HumanosRESUMO
Definition of asthma has radically changed in the last few years. It has been given great importance to the its inflammatory component that can become irreversible. It is not clear yet the cause of the increase in prevalence and mortality of asthma observed in developed countries despite an increase in the number and efficacy of the therapeutic resources. There is still much to do on studying of the statistics on prevalence and mortality rate of the undeveloped countries. In Latin America, asthma prevalence, in 1983 was reported in 3.5% in seven countries. We reviewed the death certificates in the state of Nuevo León, México, in the 1980's decade, and compared the total death rate with those attributed to asthma, according to the diagnostics criteria code 493 from the International Classification of Diseases. We also reviewed the clinical records of patients admitted to a general hospital (University Hospital of Monterrey, Nuevo Leon, Mexico) as well as the autopsy reports from the same time period. General mortality rate, as well as the mortality rate due to respiratory diseases (asthma, emphysema, chronic bronchitis and others) was unchanged (5.5 x 100,000 people), despite an increase of 100% in the size of the population. Asthma prevalence has increased from 1.2% in 1979 to 2.5% in 1989 (approximately 75,000 cases). From the 1,114 autopsies done in the University Hospital in the 1980's decade, none could be attributed to an asthma death. It is mandatory that other states in this country report parallel studies to ours, so we can have reliable data on prevalence and mortality rates of asthma. In doing so, we can learn the distribution and consequences of this disease.