RESUMO

OBJECTIVE: This study aimed to assess anxiety levels among women with metastatic breast cancer undergoing palliative chemotherapy. METHODS: A descriptive, prospective study was conducted at an oncology hospital in southern Brazil from September 2021 to October 2022. A total of 123 adult women receiving outpatient palliative chemotherapy were included in the study. Anxiety levels were evaluated using the State-Trait Anxiety Inventory at baseline, the fifth week, and the eleventh week of treatment. Data were analyzed using Kruskal-Wallis, Mann-Whitney, and Multiple General Regression Models. RESULTS: Women with advanced breast cancer had an average trait-anxiety score of 48.24±5.92. A progressive improvement in anxiety scores was observed throughout the treatment evaluation stages (44.90±5.89; 43.37±5.34; 42.58±5.75), with a significant difference between the evaluations (p=0.008). Significant correlations were found between trait-anxiety and work situation (p=0.010) and ovarian metastasis (p=0.022). The adjusted general regression model also showed statistical significance for baseline evaluation with offspring (p=0.045) and education level (p=0.041). CONCLUSION: Women with breast cancer undergoing palliative chemotherapy exhibited high trait-anxiety scores, which decreased significantly over the course of treatment.

Assuntos

RESUMO

BACKGROUND: Sinonasal cancers (SNC) are rare cancers with a high proportion attributable to occupational carcinogens. This study aims to describe the sociodemographic, clinical, and occupational characteristics of subjects with SNC in Brazil. METHODS: Observational study conducted with secondary data from a network of Hospital Cancer Registries. We selected epithelial/unspecified SNC records with a year of diagnosis from 2007 to 2021. We performed descriptive statistics of SNC cases and calculated crude and age-standardized rates (ASR, standard: world population) by gender and Region of residence. RESULTS: We identified 2,384 cases, 1,553 (65.1%) in men and 831 (34.9%) in women. The mean age at diagnosis was 59 years for both. Most SNC (50.7% in men and 53.2% in women) originated from the maxillary sinus. Most (65.5% in men and 54.5% in women) were squamous cell carcinomas. Information on occupation was missing in the years 2019-2021. Most male SNC patients (44.8%) were employed in group 6 (Agricultural, forestry, and fishing workers), while women had been mainly (34.6%) working in groups 8 (Workers in the production of industrial goods and services, machine operators) and in group 6 (27.6%). Crude SNC incidence rates were 1.0 per million person-years in men and 0.5 in women, while ASR were 1.0 and 0.4, respectively. In both genders, the highest ASR was in Minas Gerais (men: 1.9; women: 0.7). CONCLUSIONS: Establishing the profile of Brazilians with sinonasal cancer can stimulate epidemiologic research for monitoring this group of cancers with a high association with occupational exposures.

Assuntos

RESUMO

O Transplante de Células Tronco Hematopoéticas, é um tratamento complexo, com a finalidade curativa de doenças malignas e benignas, que afeta diretamente a qualidade de vida dos pacientes e cuidadores. Estudos anteriores ao período pandêmico apresentaram aspectos da sobrecarga do cuidador e qualidade de vida de ambos, esta pesquisa presente contribui para esta lacuna sobre a temática durante a pandemia. Avaliar e correlacionar a qualidade de vida de transplantados de células-tronco hematopoéticas com a qualidade de vida e sobrecarga dos cuidadores durante à pandemia de COVID-19. Série de casos com 16 díades, realizada num hospital público do Brasil, referência na América Latina. A qualidade de vida dos transplantados foi avaliada com o Functional Assessment Cancer Therapy-Bone Marrow Transplantation, já dos cuidadores com o Medical Outcomes Studt 36-Item Short Form Health Survey, a sobrecarga com o Zarit Burden Interview. Observou-se menor percepção no bem-estar funcional dos transplantados e pior estado geral de saúde dos cuidadores; a saúde mental do cuidador interferiu em diferentes domínios da qualidade de vida; houve correlação negativa entre a qualidade de vida e sobrecarga do cuidador. A pandemia impactou na qualidade de vida das díades; há necessidade de suporte adicional tanto para o paciente, quanto para o cuidador.

Hematopoietic Stem Cell Transplantation is a complex treatment, aimed at curing malignant and benign diseases, which directly affects the quality of life of patients and caregivers. Studies prior to the pandemic period presented aspects of caregiver burden and quality of life for both; this current research contributes to this gap on the topic during the pandemic. To evaluate and correlate the quality of life of hematopoietic stem cell transplant recipients with the quality of life and caregiver burden during the COVID-19 pandemic. Case series with 16 dyads, carried out in a public hospital in Brazil, a reference in Latin America. The quality of life of transplant recipients was assessed with the Functional Assessment Cancer Therapy-Bone Marrow Transplantation, caregivers with the Medical Outcomes Studt 36-Item Short Form Health Survey, burden with the Zarit Burden Interview. There was a lower perception of the functional well-being of transplant recipients and a worse general health status of caregivers; the caregiver's mental health interfered in different domains of quality of life; there was a negative correlation between quality of life and caregiver burden. The pandemic impacted the dyads' quality of life; there is a need for additional support for both the patient and the caregiver.

RESUMO

Objetivos:Construir e validar um protocolo de cuidados de enfermagem a pacientes adultos que sofreram queimaduras em um hospital público na Região Norte do Brasil e avaliar sua aplicabilidade. Método: Estudo metodológico que seguiu as etapas: construção do instrumento; validação do conteúdo utilizando a ferramenta de avaliação Appraisal of Guidelines for Research & Evaluation II (AGREE II); e análise de aplicabilidade com questionário semiestruturado com a equipe de enfermagem e por concordância e teste de Kappa. Resultados: Na etapa diagnóstico situacional, o protocolo foi elaborado com base na revisão de literatura e validado pelos especialistas por meio do instrumento AGREE II, com valor de índice de validade de conteúdo geral de 0,93, e da análise de aplicabilidade com análise de teste de Kappa, obtendo o valor de 0,81, com a concordância quase perfeita. Conclusão: O protocolo foi estruturado com qualidade para guiar a equipe de enfermagem na assistência ao paciente queimado, e indica-se, portanto, a sua utilização.

Objective:To build and validate a nursing care protocol to adult patients who suffered burns in a public hospital in the North region of Brazil and evaluate its applicability. Method: Methodological study that followed the steps: construction of the instrument; content validation using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) assessment tool; and applicability analysis with a semi-structured questionnaire with the nursing team and by agreement and Kappa test. Results: In the situational diagnosis stage, the protocol was elaborated based on the literature review and validated by the specialists through the AGREE II instrument with a general content validity index value of 0.93 and through the analysis of applicability with Kappa test analysis, obtaining a value of 0.81, with almost perfect agreement. Conclusion: The protocol was structured with quality to guide the nursing team in assisting burned patients. Therefore, its use is indicated

Objetivo:Construir, validar y evaluar la aplicabilidad de un protocolo de atención de enfermería a pacientes adultos que sufrieron quemaduras en un hospital público de la región Norte de Brasil. Método: Estudio metodológico que siguió los siguientes pasos: construcción del instrumento; validación de contenido utilizando la herramienta de evaluación AGREE II; y análisis de aplicabilidad con cuestionario semiestructurado con el equipo de enfermería y de acuerdo y test KAPPA. Resultados: Desde la etapa de diagnóstico situacional, el protocolo fue elaborado con base en la revisión bibliográfica y validado por los especialistas a través del instrumento AGREE II con un valor de Índice de Validez de Contenido General (IVC) de 0,93 y mediante el análisis de aplicabilidad con el análisis del Test Kappa, obteniendo un valor de 0.81, con concordancia casi perfecta. Conclusión: El protocolo fue estructurado con calidad para orientar al equipo de enfermería en el cuidado del paciente quemado y, por tanto, está indicado su uso.

Assuntos

RESUMO

Objetivo: evaluar y correlacionar la calidad de vida y la toxicidad financiera de pacientes adultos sometidos a trasplante de células madre hematopoyéticas durante el período de la pandemia de COVID-19. Método: estudio observacional, analítico, realizado con 35 pacientes en un hospital de referencia para trasplante en Latinoamérica. Para la recolección de datos, se utilizaron los cuestionarios Functional Assessment Cancer Therapy Bone Marrow Transplantation y el COmprehensive Score for financial Toxicity. Para el análisis de los datos se utilizaron las pruebas de correlación de Spearman y Mann-Whitney. Resultados: la calidad de vida general durante la COVID-19 mostró un puntaje bajo (67,09/108) con mayor deterioro en el bienestar funcional (14,47/28), bienestar social (16,76/28) y preocupaciones adicionales (23,41/40). Los promedios del grupo alogénico fueron inferiores a los del grupo autólogo en todos los dominios, presentando diferencia significativa en relación a preocupaciones adicionales (p=0,01) y en el índice de evaluación del tratamiento (p=0,04). Se consideró que la toxicidad financiera tenía un impacto leve (22.11/44). Se observó una relación, aunque no significativa, entre la calidad de vida y la toxicidad financiera (p=0,051). Conclusión: la calidad de vida de la muestra fue baja; existe una correlación entre la calidad de vida y la toxicidad financiera, aunque no significativa. Cuanto mayor es la toxicidad financiera, menor es la calidad de vida.

Objective: to evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic. Method: observational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis. Results: general quality of life during COVID-19 had a low score (67.09/108) with greater impairment in functional well-being (14.47/28), social well-being (16.76/28) and additional concerns (23.41/40). The means of the allogeneic group were lower than those of the autologous group in all domains, showing a significant difference in relation to additional concerns (p=0.01) and in the treatment evaluation index (p=0.04). Financial toxicity was considered to have a slight impact (22.11/44). There was a relationship, albeit not significant, between quality of life and financial toxicity (p=0.051). Conclusion: the quality of life of the sample was low; there is a correlation between quality of life and financial toxicity, although not significant. The higher the financial toxicity, the lower the quality of life.

Objetivo: avaliar e correlacionar a qualidade de vida e a toxicidade financeira dos pacientes adultos submetidos ao transplante de células-tronco hematopoéticas no período da pandemia de COVID-19. Método: estudo observacional, analítico, realizado com 35 pacientes em um hospital de referência para o transplante na América Latina. Para coleta de dados, utilizaram-se os questionários Functional Assessment Cancer Therapy Bone Marrow Transplantation e COmprehensive Score for financial Toxicity. Na análise dos dados empregaram-se os testes de correlação de Spearman e Mann-Whitney. Resultados: a qualidade de vida geral, durante a COVID-19, apresentou baixo escore (67,09/108), com maior comprometimento nas funções bem-estar funcional (14,47/28), social (16,76/28) e preocupações adicionais (23,41/40). As médias do grupo alogênico foram inferiores às do autólogo em todos os domínios, apresentando diferença significativa em relação às preocupações adicionais (p=0,01) e ao índice de avaliação do tratamento (p=0,04). A toxicidade financeira foi considerada de impacto leve (22,11/44). Observou-se relação, ainda que não significativa, entre a qualidade de vida e a toxicidade financeira (p=0,051). Conclusão: a qualidade de vida da amostra foi baixa, logo há uma correlação entre qualidade de vida e a toxicidade financeira, embora não significativa. Quanto maior a toxicidade financeira, menor a qualidade de vida.

Assuntos

RESUMO

OBJECTIVES: to evaluate the effect of guided imagery relaxation through virtual reality on anxiety in women with cervical cancer undergoing radiochemotherapy. METHODS: randomized, non-blinded, single-center clinical trial conducted at a cancer reference hospital. 52 women participated, with randomized allocation of 24 in the control group and 28 in the experimental group (12 sessions of guided imagery relaxation through virtual reality, applied three times a week). The outcome was evaluated using the State-Trait Anxiety Inventory and statistical analysis was performed using the Generalized Linear Mixed Model. RESULTS: n the experimental group, women presented significant anxiety traits (p=0.010) before the intervention. Between the 4th and 12th week of follow-up, there was a reduction in anxiety levels, without statistical significance. CONCLUSIONS: guided imagery relaxation through virtual reality provided evidence of anxiety reduction in women with cervical cancer undergoing radiochemotherapy and may contribute to clinical practice. Brazilian Clinical Trial Registry: RBR-7ssvytb.

Assuntos

RESUMO

OBJECTIVE: to evaluate and correlate the quality of life and financial toxicity of adult patients undergoing hematopoietic stem cell transplantation during the COVID-19 pandemic. METHOD: observational, analytical study, carried out with 35 patients in a reference hospital for transplantation in Latin America. For data collection, the Functional Assessment Cancer Therapy Bone Marrow Transplantation and COmprehensive Score for Financial Toxicity questionnaires were used. Spearman and Mann-Whitney correlation tests were used for data analysis. RESULTS: general quality of life during COVID-19 had a low score (67.09/108) with greater impairment in functional well-being (14.47/28), social well-being (16.76/28) and additional concerns (23.41/40). The means of the allogeneic group were lower than those of the autologous group in all domains, showing a significant difference in relation to additional concerns (p=0.01) and in the treatment evaluation index (p=0.04). Financial toxicity was considered to have a slight impact (22.11/44). There was a relationship, albeit not significant, between quality of life and financial toxicity (p=0.051). CONCLUSION: the quality of life of the sample was low; there is a correlation between quality of life and financial toxicity, although not significant. The higher the financial toxicity, the lower the quality of life.

Assuntos

RESUMO

ABSTRACT Objectives: to evaluate the effect of guided imagery relaxation through virtual reality on anxiety in women with cervical cancer undergoing radiochemotherapy. Methods: randomized, non-blinded, single-center clinical trial conducted at a cancer reference hospital. 52 women participated, with randomized allocation of 24 in the control group and 28 in the experimental group (12 sessions of guided imagery relaxation through virtual reality, applied three times a week). The outcome was evaluated using the State-Trait Anxiety Inventory and statistical analysis was performed using the Generalized Linear Mixed Model. Results: n the experimental group, women presented significant anxiety traits (p=0.010) before the intervention. Between the 4th and 12th week of follow-up, there was a reduction in anxiety levels, without statistical significance. Conclusions: guided imagery relaxation through virtual reality provided evidence of anxiety reduction in women with cervical cancer undergoing radiochemotherapy and may contribute to clinical practice. Brazilian Clinical Trial Registry: RBR-7ssvytb.

RESUMEN Objetivos: evaluar el efecto de la relajación con imagen guiada por realidad virtual en la ansiedad en mujeres con cáncer cervical sometidas a radioterapia. Métodos: ensayo clínico aleatorizado, no enmascarado, unicéntrico, realizado en un hospital de referencia en cáncer. Participaron 52 mujeres con asignación aleatoria, 24 en el grupo control y 28 en el experimental (12 sesiones de relajación por imagen guiada por realidad virtual, aplicadas 3 veces por semana). El resultado fue evaluado por el Inventario de Ansiedad Rasgo-Estado y el análisis estadístico fue realizado con el Generalized Linear Mixed Model. Resultados: en el grupo experimental, las mujeres presentaban rasgos de ansiedad significativos (p=0,010) antes de la intervención. Entre la 4ª y 12ª semana de seguimiento, hubo reducción en el estado de ansiedad, sin significancia estadística. Conclusiones: la técnica de relajación por imagen guiada por realidad virtual proporcionó evidencias de reducción de la ansiedad en mujeres con cáncer cervical en tratamiento con radioterapia y puede contribuir en la práctica clínica. Registro Brasileño de Ensayo Clínico: RBR-7ssvytb.

RESUMO Objetivos: avaliar o efeito do relaxamento com imagem guiada por realidade virtual na ansiedade em mulheres com câncer cervical submetidas à radioquimioterapia. Métodos: ensaio clínico randomizado, não mascarado, unicêntrico, realizado em um hospital de referência em câncer. Participaram 52 mulheres com alocação randomizada, 24 no grupo controle e 28 no experimental (12 sessões de relaxamento por imagem guiada por realidade virtual, aplicadas 3 vezes por semana). O desfecho foi avaliado pelo Inventário de Ansiedade Traço-Estado e a análise estatística foi realizada com o Generalized Linear Mixed Model. Resultados: no grupo experimental, as mulheres apresentavam traços de ansiedade significativos (p=0,010) antes da intervenção. Entre a 4ª e 12ª semana de seguimento, houve redução no estado de ansiedade, sem significância estatística. Conclusões: a técnica de relaxamento por imagem guiada por realidade virtual forneceu evidências de redução da ansiedade em mulheres com câncer cervical em tratamento com radioquimioterapia e pode contribuir na prática clínica. Registro Brasileiro de Ensaio Clínico: RBR-7ssvytb.

RESUMO

Introdução: Pacientes com câncer enfrentam percurso terapêutico longo e de alto nível de complexidade. Diante desse cenário, a satisfação com o tratamento hospitalar é um processo importante na recuperação da saúde, dada a possibilidade de se obter informações essenciais referentes às experiências de quem recebe o tratamento, as quais auxiliarão na adequação de condutas para prática da assistência de qualidade com possíveis implicações na qualidade de vida relacionada à saúde (QVRS). Objetivo: Analisar a QVRS e sua relação com a satisfação com o tratamento hospitalar de adultos com câncer. Método: Estudo observacional, analítico, de recorte transversal, realizado com 120 pacientes em tratamento clínico ou cirúrgico em um hospital referência no tratamento onco-hematológico localizado no Sul do Brasil, entre agosto de 2021 e janeiro de 2022. Foram utilizados os instrumentos Quality of Life Questionnaire Core 30 e Satisfaction with In-Patient Cancer Care, analisados descritivamente e por teste de correlação de Spearman. Resultados: A qualidade de vida global apresentou baixos escores (58,54/100) e maior comprometimento no domínio função social (44,17/100). Houve alto nível de satisfação com a equipe médica e de enfermagem, e maiores médias na escala habilidades técnicas (89,44/100 e 86,67/100, respectivamente). Verificou-se significância estatística entre a qualidade de vida global e todos os itens do instrumento de satisfação (p<0,05). Conclusão: A satisfação com o tratamento hospitalar impacta na qualidade de vida de adultos com câncer. Reconhecer as alterações na qualidade de vida e os determinantes que compõem a satisfação ao tratamento hospitalar pode contribuir para o aperfeiçoamento da assistência prestada.

Introduction: Patients with cancer face a long and high level of complexity therapeutic path. Given this scenario, satisfaction with hospital treatment is an important process in the recovery of health, because of the possibility of obtaining essential information about the experiences of those receiving treatment, which will help to match the conduct for the practice of quality care with possible implications for health-related quality of life (HRQL). Objective: To analyze the HRQL and its relationship with satisfaction with hospital treatment of adults with cancer. Method: Observational, analytical cross-sectional study conducted with 120 patients undergoing clinical or surgical treatment at a reference hospital of oncohematological treatment located in Southern Brazil between August 2021 and January 2022. The instruments used were Quality of Life Questionnaire Core 30 and Satisfaction with In-Patient Cancer Care, analyzed descriptively and by Spearman correlation test. Results: Global quality of life had low scores (58.54/100), greater impairment of the social functioning domain (44.17/100). There was a high level of satisfaction with medical and nursing staff, higher averages of the technical skills scale (89.44/100 and 86.67/100, respectively). Statistical significance was found between global quality of life and all items of the satisfaction instrument (p<0.05). Conclusion: Satisfaction with hospital treatment impacts the quality of life of adults with cancer. Recognizing changes in quality of life and determinants of the satisfaction with hospital treatment can contribute to improve the care provided.

Introducción: Los pacientes con cáncer enfrentan una larga y compleja experiencia terapéutica. Ante ese escenario, la satisfacción con el tratamiento hospitalario es un proceso importante en la recuperación de la salud, dada la posibilidad de obtener informaciones esenciales referentes a las experiencias de quien recibe el tratamiento, las cuales ayudarán en la adecuación de conductas para la práctica de la asistencia de calidad con posibles implicaciones en la calidad de vida relacionada con la salud (CVRS). Objetivo: Analizar la CVRS y su relación con la satisfacción con el tratamiento hospitalario de adultos con cáncer. Método: Estudio observacional, analítico, de corte transversal, realizado con 120 pacientes en tratamiento clínico o quirúrgico en un hospital referencia en el tratamiento oncohematológico localizado en el Sur de Brasil, entre agosto de 2021 y enero de 2022. Se utilizaron los instrumentos Quality of Life Questionnaire Core 30 y Satisfaction with In-Patient Cancer Care, analizados descriptivamente y por prueba de correlación de Spearman. Resultados: La calidad de vida global presentó bajas puntuaciones (58,54/100), mayor comprometimiento en el dominio función social (44,17/100). Hubo un alto nivel de satisfacción con el personal médico y de enfermería, mayores promedios en la escala habilidades técnicas (89,44/100 y 86,67/100, respectivamente). Se verificó significación estadística entre la calidad de vida global y todos los ítems del instrumento de satisfacción (p<0,05). Conclusión: La satisfacción con el tratamiento hospitalario impacta en la calidad de vida de adultos con cáncer. Reconocer los cambios en la calidad de vida y determinantes que componen la satisfacción al tratamiento hospitalario puede contribuir a mejorar la asistencia prestada.

Assuntos

RESUMO

OBJECTIVE: To analyze the effects of the technique of virtual reality guided imagery in the vital signs of hematopoietic stem-cell transplantation patients. METHOD: Quasi-experimental study with 35 participants who received an intervention using virtual reality guided imagery with progressive muscle relaxation, applied three times a week for four weeks in a referral hospital for transplants in the south of Brazil. Data collected included: temperature, arterial pressure, respiratory rate, heart rate, pain, and oxygen saturation, before and after each intervention. The comparisons were analyzed using Wilcoxon's test. RESULTS: There was a clinical significance between the mean measurements before and after for respiratory rate (p=0.00) in all stages, and for the variables Heart rate, Temperature, and Oxygen saturation from the 1st to the 12th measurements (p=0.05). CONCLUSION: The intervention was low cost, easy to apply, and showed positive effects, presenting itself as an option for patient-focused care.

Assuntos