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Mediante captura y examen de pequeños mamíferos de la Ciudad de Morelia, Michoaan, República Mexicana, se encontraron parasitados por diversos helmintos, céstodos y nemátodos, así como por protozoos de los que también afectan al hombre. Los principales mamíferos capturados fueron Rattus norvegicus y Rattus rattus, encontrándose parasitados principalmente por Trichinella spiralis 60 por ciento, Hymenolepis diminuta 45 por ciento, e Hymenolepis nana 1.3 por ciento. Se señala la importancia que tienen este tipo de estudios, para determinar los mamíferos que funcionan como reservorios de zoonosis y fuente de infección para el hombre en la Ciudad de Morelia, Michoacán, República Mexicana y de otras localidades del país

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Due to the importance of cysticercosis in Mexico and Latin America and to the fact that in the last years another mechanism of infection for this disease has been proposed, i.e. through postoncospheres and immunosuppression of the host, we have considered relevant to perform the present work, which consisted in assessing the immune response induced by dexamethasone as well as that produced by parasites in pigs infected with T. solium eggs, or postoncosphere-infected, and in postoncosphere-infected and dexamethasone-treated animals. We used 10 recently weaned pigs, three were used as controls, two of them without the drug and one with it; two were infected with T. solium eggs; five with postoncospheres receiving also dexamethasone three of them. We evaluated the humoral response against parasite antigen using indirect haemagglutination (IH) and ELISA methods. Results of the immune humoral response revealed titres of up to 1:128 in T. solium eggs infected animals, of 1:16 in postoncosphere infected animals, and of 1:32 towards the end of the experiment in postoncosphere plus dexamethasone animals. Absorbance titres with ELISA confirmed these findings. Data obtained by IH show that the antibody titres of the pigs challenged with postoncospheres and postoncospheres plus dexamethasone are positive as compared to the titres obtained in the pigs infected with T. solium eggs. Results from the ELISA confirmed this finding, since, from weeks 14 to 17, the pigs became positive, behaving as those pigs that developed cysticercosis. This is relevant as it indicates that the antiposcosphere antibodies recognized antigens of T. solium larvae.

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Toxocariosis is a zoonosis which has been widely studied in dogs. However, not much is known about this parasitosis in cats. The aim of the present work was to determine the frequency of Toxocara cati in domestic cats in Mexico City and the State of Mexico. Feces of 660 domestic cats were studied by the Faust concentration-floating test; 401 samples were from cats living in Mexico City of which 308 lived in houses and 93 in apartments; 231 were from urban areas of the State of Mexico and 28 from a rural area of the same state. The total frequency of T. cati eggs obtained from domestic cats in Mexico City was 42.9%; in cats living in apartments it was 18.3% and in cats living in houses it was 50.3%. In domestic cats from the State of Mexico, T. cati frequency was 36.4% in the urban and 21.4% in the rural areas. We consider that toxocariosis frequency observed at the two studied sites is high and that the need to prevent dissemination of the infectious forms of T. cati is urgent, as is the necessity of informing the population of the risk of living with T. cati parasited animals and of the anatomopathological alterations caused by T. cati in man.

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An analytic relationship between positivity of the indirect immunofluorescent test (IIFT) for toxoplasmosis and clinical findings in a population of 328 children with cerebral infantile palsy (CIP) was performed. Children were distributed by age in one of four groups: I (0-2 years); II (3-6 years); III (7-12 years) and IV (13-18 years). One control group of 168 children with no PCI clinical findings was included. 125 sera were positive at 1:64 dilutions. The study of the binomial mother-child of 40 cases rendered 26 mothers with significant titer values. The majority of positive mothers to IIFT correlated with the youngest children (Groups I, II and III), mainly with group I (70.0%), which showed the highest titer ranges. Correlation between positive IIFT and clinical features was as high as 100.0%.

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The present integral clinical and laboratory study was carried out in 325 children infected with Hymenolepis nana. Results showed that H. nana is found among the top five intestinal parasitosis in school children in Mexico City, in the majority of the cases associated with protozoans and other helminths, especially and with Giardia lamblia. Although the amount of parasites found is small, the clinical manifestations vary very little with larger amounts. The most important and more constant clinical manifestations in those solely infected with H. nana and with other combinations are: abdominal pain, hyporexia and irritability. We have seen that in patients infected solely with H. nana, there is weight loss, meteorism and flatulences. In those associated with G. lamblia, diarrhea is one of the most frequent manifestations. Hymenolepiasis is an important disease in our environment due to its high frequency among pre-school and school children and its constant identifiable clinical manifestations.

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Con el objeto de correlacionar la presencia de neurocisticercosis en individuos catalogados como inválidos para el trabajo y el antecedente de haber laborado con o en presencia de disolventes orgánicos como posible causa desencadenante de la patología señalada, se estudiaron 20 individuos que fueron clasificados como inválidos a causa del diagnóstico de cisticercosis cerebral. El estudio se llevó a cabo por medio de interrogatorio directo o indirecto a cada individuo, revisión de su expediente clínico, serología para cisticercosis, examen psicológico para valoración del rendimiento intelectual

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Twenty individuals classified as disabled due to diagnosed cerebral cysticercosis were studied to correlate the presence of neurocysticercosis with the history of having worked in contact with organic solvents as possible triggering agents of the pathology. The study was performed by direct or indirect interrogatory, review of the case histories, serologic examinations, and psychological evaluation of the intellectual performance level and psychopathological index. Of the 20 subjects, 50% had been exposed to organic solvents in their work; all had been in contact with the infecting parasite, either through frequent consumption of pork meat, or through contact with fecal mass. The titers of the haemagglutination test varied from 1:2 to 1:256, being the diagnosis value of > or = 1:16. There was also a variation as a function of the antigen used for the sera tests performed in the sampled subjects, such as complete or incomplete somatic antigen, vesicular fluid, and excretions and secretions. Other variations found, such as symptoms and the results of the psychological evaluation are depicted in tables. It is concluded that in these cases, neurocysticercosis is an invalidating disease, and the presence of organic solvents is emphasized as an important factor of the disease or as a triggering factor.

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RESUMEN El estudio de 60 muestras de líquido cefalorraquídeo tomadas al azar provenientes de enfermos de neurocisticercosís, mostró que las pruebas inmunológicas detectan un número importante de casos de esta enfermedad; especialmente si se comparan con las pruebas citoquímicas utilizadas tradicionalmente como auxiliares de diagnóstico. No obstante que la reactividad de la técnica de aglutinación de partículas de látex en este trabajo descendió de 88% a 77%en la detección de antígenos solubles de Cysticercus cellulosae en el líquido cefalorraquídeo. fue superior a la reacción de fijación del complemento que detectó anticuerpos en 60% de los casos. Ambas pruebas se incrementaron 10% en la segunda muestra !o que parece indicar aumento en la concentración de antígenos de C. cellulosae después del tratamiento, así como rápida producción de anticuerpos específicos in su

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