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Resumen Antecedentes: Los trastornos mentales constituyen una de las principales causas de años vividos con discapacidad, si bien no se dispone de estimaciones recientes sobre su magnitud. Objetivo: Reportar las tendencias de prevalencia de trastornos mentales, los años vividos con discapacidad y los años de vida saludables perdidos por sexo, edad y entidad federativa de México. Material y métodos: Se utilizó la base de datos para México del Global Burden of Disease. Resultados: Se calcularon 18.1 millones de personas con algún trastorno mental en 2021, que representaron un incremento de 15.4 % respecto a 2019. Los trastornos depresivos y de ansiedad aumentaron de manera notable entre 2019 y 2021, lo cual posiblemente esté relacionado con COVID-19, el confinamiento y los duelos vividos durante la pandemia. Conclusiones: Los trastornos mentales se han incrementado considerablemente desde la única encuesta nacional de salud mental que utilizó criterios diagnósticos para evaluar las prevalencias. Es importante invertir en estudios epidemiológicos, prevención y atención de los trastornos mentales, los cuales se encuentran entre las primeras causas de años vividos con discapacidad en el país.
Abstract Background: Mental disorders are one of the main causes of years lived with disability, although there is a lack of recent estimates of their magnitude. Objective: To report the trends of mental disorders prevalence, years lived with disability and years of healthy life lost by sex, age and state in Mexico. Material and methods: The Global Burden of Disease database for Mexico was used. Results: There were an estimated 18.1 million persons with some mental disorder in 2021, which represented an increase of 15.4% in comparison with 2019. Depressive and anxiety disorders did significantly increase between 2019 and 2021, which is possibly related to COVID-19, the confinement and the situations of grief experienced during the pandemic. Conclusions: Mental disorders have considerably increased since the only national mental health survey that used diagnostic criteria to evaluate their prevalence. It is important to invest in epidemiological studies, prevention and care of mental disorders, which are among the leading causes of years lived with disability in the country.
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La personalidad tipo D se refiere a la vulnerabilidad frente al estrés psicológico, la cual se expresa en dos componentes: la afectividad negativa (AN) y la inhibición social (is), que pueden desencadenar un estado de estrés psicosocial que afecta la salud. El objetivo de este estudio fue analizar las propiedades psicométricas de la Escala de Personalidad Tipo D (DS-14) en población adulta colombiana. La muestra estuvo conformada por 456 adultos (41.7 % hombres y 58.3 % mujeres) colombianos entre los 18 y 86 años. El coeficiente de fiabilidad para las dos subescalas de la DS-14 fue de .73 (AN) y .72 (IS), y .79 para el puntaje total. Se analizó la validez concurrente con medidas de estrategias de afrontamiento resiliente y afrontamiento religioso. Los resultados evidencian validez interna y externa, dados los índices del análisis factorial exploratorio y confirmatorio.
Type D personality refers to vulnerability to psychological stress, which is expressed in two components: negative affectivity (NA) and social inhibition (si), which can trigger a state of psychosocial stress that affects health. The aim of this study was to analyze the psychometric properties of the Type D Personality Scale (DS-14) in the Colombian adult population. The sample consisted of 456 colombian adults (41.7 °% men and 58.3 °% women) between 18 and 86 years of age. The reliability coefficient for the two subscales of the DS-14 was .73 (NA) and .72 (SI), and .79 for the total score. Concurrent validity was analyzed with measures of resilient coping strategies and religious coping. The results show internal and external validity given the indices of the exploratory and confirmatory factor analysis.
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Fragile X syndrome is caused by the expansion of CGG triplets in the FMR1 gene, which generates epigenetic changes that silence its expression. The absence of the protein coded by this gene, FMRP, causes cellular dysfunction, leading to impaired brain development and functional abnormalities. The physical and neurologic manifestations of the disease appear early in life and may suggest the diagnosis. However, it must be confirmed by molecular tests. It affects multiple areas of daily living and greatly burdens the affected individuals and their families. Fragile X syndrome is the most common monogenic cause of intellectual disability and autism spectrum disorder; the diagnosis should be suspected in every patient with neurodevelopmental delay. Early interventions could improve the functional prognosis of patients with Fragile X syndrome, significantly impacting their quality of life and daily functioning. Therefore, healthcare for children with Fragile X syndrome should include a multidisciplinary approach.
El síndrome de X frágil es causado por la expansión de tripletas CGG en el gen FMR1, el cual genera cambios epigenéticos que silencian su expresión. La ausencia de la proteína codificada por este gen, la FMRP, causa disfunción celular, llevando a deficiencia en el desarrollo cerebral y anormalidades funcionales. Las manifestaciones físicas y neurológicas de la enfermedad aparecen en edades tempranas y pueden sugerir el diagnóstico. Sin embargo, este debe ser confirmado por pruebas moleculares. El síndrome afecta múltiples aspectos de la vida diaria y representa una alta carga para los individuos afectados y para sus familias. El síndrome de C frágil es la causa monogénica más común de discapacidad intelectual y trastornos del espectro autista; por ende, el diagnóstico debe sospecharse en todo paciente con retraso del neurodesarrollo. Intervenciones tempranas podrían mejorar el pronóstico funcional de pacientes con síndrome de X frágil, impactando significativamente su calidad de vida y funcionamiento. Por lo tanto, la atención en salud de niños con síndrome de X frágil debe incluir un abordaje multidisciplinario.
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Transtorno do Espectro Autista , Síndrome do Cromossomo X Frágil , Deficiência Intelectual , Humanos , Criança , Síndrome do Cromossomo X Frágil/diagnóstico , Síndrome do Cromossomo X Frágil/genética , Transtorno do Espectro Autista/etiologia , Transtorno do Espectro Autista/genética , Qualidade de Vida , Proteína do X Frágil da Deficiência Intelectual/genéticaRESUMO
Resumen La resiliencia es la competencia de afrontamiento y adaptación a las condiciones estresantes que puede experimentar una persona. Se puede expresar a través de varias estrategias como el optimismo, la perseverancia, la creatividad y el crecimiento positivo frente a la adversidad. Esta investigación tuvo como objetivo analizar las propiedades psicométricas de la Escala Breve de Estrategias Resilientes (BRCS) en población adulta colombiana. La muestra estuvo conformada por 456 adultos colombianos (41.7 % hombres y 58.3 % mujeres) entre los 18 y los 86 años (M = 46.99). El coeficiente de fiabilidad para el puntaje total de las dos subescalas de la BRCS fue de .77. Se corroboró la validez del constructo a través de la bondad de ajuste del modelo de un factor y la correlación entre los cuatro ítems, por el que se confirmó la estructura del modelo propuesto por Sinclair y Wallston (2004). Se analizó la validez concurrente con medidas de afrontamiento religioso y personalidad Tipo D. Se efectuó un análisis de la discriminación de los reactivos a través del coeficiente de correlación biserial, que indicó que las correlaciones del ítem con la escala total tienen un nivel de discriminación excelente, con valores entre .740 y .807. Los resultados muestran correlaciones significativas entre la resiliencia y el afrontamiento religioso positivo, índices de confiabilidad interna aceptables y consistencia interna, dados los índices del análisis factorial confirmatorio. Se concluye que la evidencia sugiere que la escala BRCS es un instrumento válido y confiable para la evaluación de la capacidad de resiliencia en adultos colombianos.
Abstract Resilience is the ability to cope and adapt to stressful situations that a person may experience. This ability can be expressed through several strategies such as optimism, perseverance, creativity, and positive growth from adversity. Considering the few studies on this subject in the Latin American context and, therefore, the difficulties in evaluating resilient strategies in adults, this research considered to analyze the psychometric characteristics of the Brief Resilient Strategies Scale (BRCS). This study aimed to analyze the psychometric properties of the "Brief Resilient Coping Scale (BRCS)" in the Colombian adult population. The sample consisted of 456 Colombian adults (41.7 % men and 58.3 % women) between 18 and 86 years old (M = 46.99). The reliability coefficient for the total score of the two BRCS subscales was .77. The construct validity was confirmed by goodness of fit results for applying a one-factor model to the scale and the correlation between the four items, confirming the structure of the model proposed by Sinclair y Wallston (2004), the initial solution of a factor was confirmed, with the same items loading the same factor and with factorial weights greater than .3. Likewise, all the values of the goodness of fit indices are within the accepted ranges for a good fit of the model. That is, the data fit the factorial model well. The concurrent validity was analyzed with measures of religious coping and type D personality. Positive correlations of the BRCS scale were found with positive religious coping of the RCOPE, indicating that a greater resilience, more expression of a sense of spirituality. In the same way, the BRCS scale correlates with the DS-14 scale, indicating that a greater resilience, less tendency to experience negative emotions such as dysphoria, tension, worry, irritability, and anger more extensively over time. In addition, the correlations indicated that a higher resilience, lower vulnerability to psychological stress with experiences of strong negative emotions and inhibition of their expression in interaction with other people. The results of the criterion validity suggest that people who use resilient strategies and religious coping are protective factors for the physical and mental health of the adult population, in such a way that people with higher levels of resilience may have a greater expression of a sense spiritual. Likewise, the most resilient subjects use variables such as satisfaction with life, humor, perceived personal competence, optimism, among others, indicative of a heightened sense of internal coherence. Also, the subjects who demonstrated greater resilience capacity were less vulnerable to experiencing negative affect and social inhibition. In general terms, these results suggest that the use of resilient strategies is related to constructs that are theoretically expected from a clinical and mental health perspective. The results show significant correlations between resilience and positive religious coping, acceptable internal reliability indices and internal consistency given the confirmatory factor analysis indices. An item discrimination analysis was performed through the biserial correlation coefficient, the correlations of the item with the total scale have an excellent level of discrimination, with values between .740 and .807. For data analysis, IBM SPSS Software®, Version 25, the R for Statistical Computing program (R Project, 2019) and LISREL 8.80 was used. The evidence suggests that the BRCS scale is a valid and reliable instrument for assessing resilience capacity in Colombian adults. In general, it was found that the BRCS has good psychometric properties in the various countries where it has been evaluated, for all the population groups analyzed, with only significant differences between men and women.
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Fragile X syndrome is caused by the expansion of CGG triplets in the FMR1 gene, which generates epigenetic changes that silence its expression. The absence of the protein coded by this gene, FMRP, causes cellular dysfunction, leading to impaired brain development and functional abnormalities. The physical and neurologic manifestations of the disease appear early in life and may suggest the diagnosis. However, it must be confirmed by molecular tests. It affects multiple areas of daily living and greatly burdens the affected individuals and their families. Fragile X syndrome is the most common monogenic cause of intellectual disability and autism spectrum disorder; the diagnosis should be suspected in every patient with neurodevelopmental delay. Early interventions could improve the functional prognosis of patients with Fragile X syndrome, significantly impacting their quality of life and daily functioning. Therefore, healthcare for children with Fragile X syndrome should include a multidisciplinary approach.
El síndrome de X frágil es causado por la expansión de tripletas CGG en el gen FMR1, el cual genera cambios epigenéticos que silencian su expresión. La ausencia de la proteína codificada por este gen, la FMRP, causa disfunción celular, llevando a deficiencia en el desarrollo cerebral y anormalidades funcionales. Las manifestaciones físicas y neurológicas de la enfermedad aparecen en edades tempranas y pueden sugerir el diagnóstico. Sin embargo, este debe ser confirmado por pruebas moleculares. El síndrome afecta múltiples aspectos de la vida diaria y representa una alta carga para los individuos afectados y para sus familias. El síndrome de C frágil es la causa monogénica más común de discapacidad intelectual y trastornos del espectro autista; por ende, el diagnóstico debe sospecharse en todo paciente con retraso del neurodesarrollo. Intervenciones tempranas podrían mejorar el pronóstico funcional de pacientes con síndrome de X frágil, impactando significativamente su calidad de vida y funcionamiento. Por lo tanto, la atención en salud de niños con síndrome de X frágil debe incluir un abordaje multidisciplinario.
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Mg-Zn co-dopedGaN powders via the nitridation of a Ga-Mg-Zn metallic solution at 1000 °C for 2 h in ammonia flow were obtained. XRD patterns for the Mg-Zn co-dopedGaN powders showed a crystal size average of 46.88 nm. Scanning electron microscopy micrographs had an irregular shape, with a ribbon-like structure and a length of 8.63 µm. Energy-dispersive spectroscopy showed the incorporation of Zn (Lα 1.012 eV) and Mg (Kα 1.253 eV), while XPS measurements showed the elemental contributions of magnesium and zinc as co-dopant elements quantified in 49.31 eV and 1019.49 eV, respectively. The photoluminescence spectrum showed a fundamental emission located at 3.40 eV(364.70 nm), which was related to band-to-band transition, besides a second emission found in a range from 2.80 eV to 2.90 eV (442.85-427.58 nm), which was related to a characteristic of Mg-doped GaN and Zn-doped GaN powders. Furthermore, Raman scattering demonstrated a shoulder at 648.05 cm-1, which could indicate the incorporation of the Mg and Zn co-dopants atoms into the GaN structure. It is expected that one of the main applications of Mg-Zn co-doped GaN powders is in obtaining thin films for SARS-CoV-2 biosensors.
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BACKGROUND: Mental disorders are one of the main causes of years lived with disability, although there is a lack of recent estimates of their magnitude. OBJECTIVE: To report the trends of mental disorders prevalence, years lived with disability and years of healthy life lost by sex, age and state in Mexico. MATERIAL AND METHODS: The Global Burden of Disease database for Mexico was used. RESULTS: There were an estimated 18.1 million persons with some mental disorder in 2021, which represented an increase of 15.4% in comparison with 2019. Depressive and anxiety disorders did significantly increase between 2019 and 2021, which is possibly related to COVID-19, the confinement and the situations of grief experienced during the pandemic. CONCLUSIONS: Mental disorders have considerably increased since the only national mental health survey that used diagnostic criteria to evaluate their prevalence. It is important to invest in epidemiological studies, prevention and care of mental disorders, which are among the leading causes of years lived with disability in the country.
ANTECEDENTES: Los trastornos mentales constituyen una de las principales causas de años vividos con discapacidad, si bien no se dispone de estimaciones recientes sobre su magnitud. OBJETIVO: Reportar las tendencias de prevalencia de trastornos mentales, los años vividos con discapacidad y los años de vida saludables perdidos por sexo, edad y entidad federativa de México. MATERIAL Y MÉTODOS: Se utilizó la base de datos para México del Global Burden of Disease. RESULTADOS: Se calcularon 18.1 millones de personas con algún trastorno mental en 2021, que representaron un incremento de 15.4 % respecto a 2019. Los trastornos depresivos y de ansiedad aumentaron de manera notable entre 2019 y 2021, lo cual posiblemente esté relacionado con COVID-19, el confinamiento y los duelos vividos durante la pandemia. CONCLUSIONES: Los trastornos mentales se han incrementado considerablemente desde la única encuesta nacional de salud mental que utilizó criterios diagnósticos para evaluar las prevalencias. Es importante invertir en estudios epidemiológicos, prevención y atención de los trastornos mentales, los cuales se encuentran entre las primeras causas de años vividos con discapacidad en el país.
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COVID-19 , Transtornos Mentais , Humanos , Carga Global da Doença , México/epidemiologia , Transtornos Mentais/epidemiologia , COVID-19/epidemiologia , Nível de Saúde , Saúde Global , PrevalênciaRESUMO
This work presents the theoretical calculation of isotherm diagrams for quaternary alloys of III-V semiconductor compounds with the form IIIxIII1-xVyV1-y. In particular, the isotherm diagrams for the AlxGa1-xAsySb1-y quaternary alloy at low temperatures were calculated (500 °C, 450 °C, 400 °C, and 350 °C). The AlxGa1-xAsySb1-y quaternary alloy was formed from four binary compounds such as GaAs, AlAs, AlSb, and GaSb, all with direct bandgaps. The regular solution approximation was used to find the quaternary isotherm diagrams, represented in four linearly independent equations, which were solved using Parametric Technology Corporation Mathcad 14.0 software for different arsenic and antimony atomic fractions. The results support the possible growth of layers via liquid-phase epitaxy in a range of temperatures from 500 °C to 350 °C, where the crystalline quality could be improved at low temperatures. These semiconductor layers could have applications for optoelectronic devices in photonic communications, thermophotovoltaic systems, and microwave devices with good crystalline quality.
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The present instrumental study evaluated the psychometric properties of the Coronavirus Anxiety Scale with 421 Colombian adults in full lockdown of coronavirus. The reliability was excellent, obtained through the Cronbach's Alpha coefficient (α = 0.83). The results of the confirmatory factor analysis identified satisfactory indicators for the scale's one-dimensional model. The correlations obtained in the discriminant analysis of the items have a moderate level of correlation with values between 0.74 and 0.81. These findings demonstrate that the Coronavirus Anxiety Scale is a valid and reliable instrument to evaluate dysfunctional anxiety related to coronavirus in Colombian population.
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Coronavirus , Adulto , Ansiedade/diagnóstico , Colômbia , Humanos , Psicometria , Reprodutibilidade dos Testes , Inquéritos e QuestionáriosRESUMO
BACKGROUND: The World Health Organization and the American Academy of Pediatrics suggest disclose the HIV diagnosis to children. However, the disclosure of HIV/AIDS diagnosis to children and adolescents, it is not a consolidated practice in Colombia, often this occurs because caregivers do not have an adequate methodology to carry out this process. AIM: We present the efficiency components validation of "Mi dragon Dormido" history in the educational process and revelation ofAIDS diagnosis to boys and girls. METHOD: By means of purposive non-probability sampling, semi-structured interviews were conducted with 40 children, with an equal number of children who were seropositive (n = 20) and seronegative (n = 20) for HIV/ AIDS. A qualitative study with the approach of grounded theory and systematic design was conducted. We conducted the qualitative study through the NVivo software, with the codification type being Tree Nodes. RESULTS: The qualitative data provided necessary approximations to improve the content and design of the tool and showed that it reflects the reality of children and allows them to identify frequent fears and questions regarding to chronic health condition of HIV. CONCLUSIONS: These results provide important information to be considered in the process of diagnosis revelation and its management by health personnel.