Assuntos
Microcefalia , Zika virus , Brasil , Humanos , Complicações Infecciosas na Gravidez , Infecção por Zika virusRESUMO
A randomized prospective clinical trial of feeder vessel photocoagulation for proliferative sickle cell retinopathy was performed. In Chicago, there were 34 argon laser-treated eyes and 30 control eyes. In Kingston, there were 53 xenon arc treated eyes and 50 control eyes. Prolonged loss of visual acuity was rare in both photocoagulated and control eyes. Argon laser and xenon arc feeder vessel photocoagulation reduced the incidence of vitreous hemorrhage and visual loss from vitreous hemorrhage. However, photocoagulation was associated with an increased risk of choroidal neovascularization (xenon arc greater than argon laser) and retinal detachment (argon laser), although visual loss from these complications has not been in these patients so far. (AU)
Assuntos
Humanos , Adulto , Masculino , Feminino , Anemia Falciforme/complicações , Lasers/uso terapêutico , Doenças Retinianas/cirurgia , Lasers/métodos , Corioide/irrigação sanguínea , Ensaios Clínicos como Assunto , Estudo Comparativo , Seguimentos , Lasers/efeitos adversos , /etiologia , Distribuição Aleatória , Descolamento Retiniano/etiologia , Doenças Retinianas/etiologiaRESUMO
Four patients had central retinal artery occlusions after retrobulbar anaesthesia with lidocaine HCl was administered before photocoagulation. One of these four had two separate episodes of closure. Only one had permanent visual loss and none had evidence of retrobulbar hemorrhage. Each patient had a severe hematologic or vascular disorder. We think that direct trauma to the central retinal artery behind the globe, the pharmacologic or compressive effects of the injected solution,or both caused the occlusions in these patients. (AU)
Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , Masculino , Feminino , Arteriopatias Oclusivas/fisiopatologia , Lidocaína/efeitos adversos , Retina/cirurgia , Artéria Retiniana/fisiopatologia , Anestesia Local/efeitos adversos , Arteriopatias Oclusivas/induzido quimicamente , Olho , Artéria Retiniana/efeitos dos fármacos , Artéria Retiniana/lesões , Doenças Retinianas/cirurgia , Injeções/efeitos adversos , Fotocoagulação/efeitos adversosRESUMO
Choroidal neovascularisation occurred in 35 out of 57 (61 percent) patients during a trial of xenon arc photocoagulation in proliferative sickle retinopathy. Nineteen patients manifested abnormal vessel systems in the plane of the retina which tended to be benign, not enlarging and without complications (choroidoretinal neovascularization). In 16 patients the abnormal vessel system grew into the vitreous, tended to increase in size and to be associated with vitreous haemorrhage and retinal traction (choroidovitreal neovascularisation). Both forms of neovascularisation were significantly more common at younger ages. Treatment was generally unsatisfactory, frequently resulting in further enlargement of the lesions. Although the natural history of choroidal neovascularisation and its ultimate effect on visual function remains to be recorded, these lesions constitute a common and potentially serious complication of xenon arc photocoagulation in proliferative sickle retinopathy as currently performed. (Summary)
Assuntos
Humanos , Adolescente , Adulto , Pessoa de Meia-Idade , Masculino , Feminino , Anemia Falciforme/cirurgia , Corioide/irrigação sanguínea , Lasers/efeitos adversos , Lasers/uso terapêutico , Fatores Etários , Angiofluoresceinografia , Seguimentos , Fatores de Tempo , Doenças da Úvea/etiologia , Doenças da Úvea/patologiaRESUMO
In two patients with sickle cell disease (one hemoglobin SC and one hemoglobin SS), central retinal artery occlusion developed. In one case, the occlusion followed a retrobular injection of lidocaine hydrochloride. Although the central retinal artery reperfused in each patient, many secondary peripheral retinal ateriolar occlusions remained. During the subsequent days, multiple salmon-patch hemorrhages developed in the distribution of these occluded arterioles. In one patient, the salmon-patch hemorrhages evolved into atrophic schisis cavities. These unusual cases allowed us to document the origin of salmon-patch hemorrhages after peripheral retinal arteriolar occlusions. The development of the hemorrhages was a delayed phenomenon that occurred hours to days after the initial vascular occlusion. Reperfusion of the damaged ischemic vessels with a blowout of the walls of the vessels seems the most likely explanation for this phenomenon. (Au)