RESUMO

Direct enzymatic assay of urinary sulfated bile acids is a sensitive, rapid, minimally invasive, and convenient method of detecting cholestasis in young infants. It may replace measurement of serum direct bilirubin for selective screening for biliary atresia and neonatal hepatitis syndrome at 1 month of age.

Assuntos

Ácidos e Sais Biliares/urina , Bilirrubina/sangue , Colestase/diagnóstico , Triagem Neonatal , Atresia Biliar/sangue , Atresia Biliar/diagnóstico , Atresia Biliar/urina , Colestase/sangue , Colestase/urina , Feminino , Hepatite/sangue , Hepatite/diagnóstico , Hepatite/urina , Humanos , Lactente , Recém-Nascido , Masculino , Sensibilidade e Especificidade , Sulfatos/urina , Síndrome