RESUMO

A carbapenem-resistant Acinetobacter baumannii strain was isolated from the peritoneal fluid of a patient with complicated intra-abdominal infection and evaluated at the Multidrug-resistant Organism Repository and Surveillance Network by whole-genome sequencing and real-time PCR. The isolate was sequence type 25 and susceptible to colistin and minocycline, with low MICs of tigecycline. blaNDM-1 was located on a plasmid with >99% homology to pNDM-BJ02. The isolate carried numerous other antibiotic resistance genes, including the 16S methylase gene, armA.

Assuntos

Infecções por Acinetobacter/microbiologia , Acinetobacter baumannii/isolamento & purificação , Peritonite/microbiologia , Plasmídeos , beta-Lactamases/genética , Infecções por Acinetobacter/diagnóstico , Infecções por Acinetobacter/tratamento farmacológico , Acinetobacter baumannii/efeitos dos fármacos , Acinetobacter baumannii/enzimologia , Acinetobacter baumannii/genética , Idoso , Antibacterianos/farmacologia , Colistina/farmacologia , Farmacorresistência Bacteriana Múltipla , Sequenciamento de Nucleotídeos em Larga Escala , Honduras , Humanos , Masculino , Metiltransferases/genética , Metiltransferases/metabolismo , Minociclina/análogos & derivados , Minociclina/farmacologia , Peritonite/diagnóstico , Peritonite/tratamento farmacológico , Tigeciclina , beta-Lactamases/metabolismo