1.
Rev. Soc. Bras. Med. Trop
; 29(1): 59-61, Jan.-Feb. 1996. tab
Artigo
em Português
| LILACS
| ID: lil-187178
Assuntos
Humanos , Animais , Feminino , Camundongos , Modelos Animais de Doenças , Doença de Chagas/diagnóstico , Laranja de Acridina , Células Sanguíneas/parasitologia , Citodiagnóstico/métodos , Estudo de Avaliação , Camundongos Endogâmicos BALB C , Microscopia de Fluorescência , Sensibilidade e Especificidade , Trypanosoma cruzi/isolamento & purificação
2.
Rev. Soc. Bras. Med. Trop
; 28(4): 351-6, Oct.-Dec. 1995. graf
Artigo
em Português
| LILACS
| ID: lil-187125
RESUMO
Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.