RESUMO
Background: Pulmonary hypoplasia is characterized by incomplete development of the lungs, owing to congenital defectsor the action of toxic substances. Moreover, it has rarely been described in pigs. Ascites or hydroperitoneum is characterized by the presence of fluid inside the abdominal cavity and does not generally cause changes in the abdominal organs.However, hydrothorax, characterized by the presence of fluid within the thoracic cavity, is responsible for the compressionof thoracic organs and consequent heart and respiratory failure. This study aims to describe a case of congenital pulmonaryhypoplasia associated with ascites and hydrothorax in a newborn pig.Case: A male neonate Landrace pig that died shortly after delivery was presented for necropsy with increased abdominalvolume and bilateral extension of the pelvic limbs. The pig belonged to a litter of 13 piglets, four of which died shortlyafter birth. The rest of the piglets were poorly developed, but only one was presented for necropsy. Significant externalchanges, along with permanent distension, interpreted as arthrogriposis, were observed in the pelvic limbs. The skin of theventral abdominal region was thin, with evidence of all blood vessels, interpreted as telangectasis. An internal examination revealed the presence of a slightly yellowish liquid in the thoracic and abdominal cavities, interpreted as hydrothoraxand ascites, respectively. The lungs were reduced in size, indicating pulmonary hypoplasia. The liver had rounded edges,which were dark red and firm, with an irregular surface. Significant microscopic findings were observed in the lungs,which were divided by fibrous connective tissue and showed evidence of small and atrophied alveoli. Furthermore, connective tissue was observed around the peribronchiolar regions and underdeveloped cartilage around the airways. The liver...(AU)
Assuntos
Animais , Suínos/anormalidades , Animais Recém-Nascidos/anormalidades , Pulmão/anormalidades , Ascite/veterinária , Hidrotórax/veterinária , Artrogripose/veterináriaRESUMO
Background: Pulmonary hypoplasia is characterized by incomplete development of the lungs, owing to congenital defectsor the action of toxic substances. Moreover, it has rarely been described in pigs. Ascites or hydroperitoneum is characterized by the presence of fluid inside the abdominal cavity and does not generally cause changes in the abdominal organs.However, hydrothorax, characterized by the presence of fluid within the thoracic cavity, is responsible for the compressionof thoracic organs and consequent heart and respiratory failure. This study aims to describe a case of congenital pulmonaryhypoplasia associated with ascites and hydrothorax in a newborn pig.Case: A male neonate Landrace pig that died shortly after delivery was presented for necropsy with increased abdominalvolume and bilateral extension of the pelvic limbs. The pig belonged to a litter of 13 piglets, four of which died shortlyafter birth. The rest of the piglets were poorly developed, but only one was presented for necropsy. Significant externalchanges, along with permanent distension, interpreted as arthrogriposis, were observed in the pelvic limbs. The skin of theventral abdominal region was thin, with evidence of all blood vessels, interpreted as telangectasis. An internal examination revealed the presence of a slightly yellowish liquid in the thoracic and abdominal cavities, interpreted as hydrothoraxand ascites, respectively. The lungs were reduced in size, indicating pulmonary hypoplasia. The liver had rounded edges,which were dark red and firm, with an irregular surface. Significant microscopic findings were observed in the lungs,which were divided by fibrous connective tissue and showed evidence of small and atrophied alveoli. Furthermore, connective tissue was observed around the peribronchiolar regions and underdeveloped cartilage around the airways. The liver...
Assuntos
Animais , Animais Recém-Nascidos/anormalidades , Pulmão/anormalidades , Suínos/anormalidades , Artrogripose/veterinária , Ascite/veterinária , Hidrotórax/veterináriaRESUMO
Background: Primary lung tumors in cats are mainly classified into adenocarcinoma arising from peripheral pulmonaryepithelium and, in a smaller number of cases, into adenosquamous or squamous carcinoma, bronchioloalveolar carcinoma,and carcinoid tumor. There are few reports in the international literature describing lung cancer metastasis to visceral organs in cats, especially with regard to squamous tumors. This report describes the clinical pathological, histological, andimmunohistochemical findings of lung squamous cell carcinoma with metastasis to small intestine in a cat.Case: A female, Siamese, unneutered, adult cat presented with an unhealed ulcerative crusted lesion on the left ear, previously diagnosed as squamous cell carcinoma (SCC). Six months later, the cat returned presenting with increased volumein the left pelvic limb and claudication due to severe osteolysis in metatarsal and tarsal bones, as shown in radiographicexaminations. The limb was amputated forty day later, but it did not undergo histological examination. The cat died fourteendays after amputation and underwent necropsy. Macroscopically, significant changes were observed in the small intestine,including serous segmental necrotizing and hemorrhagic lesion with luminal stenosis and corrugation of mucous surface,which was covered with a fibrinopurulent pseudomembrane. Palpation of lung parenchyma showed small firm nodules.There was an ulcerative crusted lesion on the left ear. Histopatological examination revealed infiltration of pleomorphicneoplastic epithelial cells disrupting the architecture of small intestine and lung, with pronounced anisocyitosis and anisokaryosis. The neoplastic cells had indistinct borders; their cytoplasm was eosinophilic and pleomorphic and varied frommoderate to abundant in amount; and their nuclei...(AU)
Assuntos
Animais , Feminino , Gatos , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/veterinária , Metástase Neoplásica , Neoplasias Pulmonares/veterinária , Intestino Delgado , Imuno-Histoquímica/veterináriaRESUMO
Background: Primary lung tumors in cats are mainly classified into adenocarcinoma arising from peripheral pulmonaryepithelium and, in a smaller number of cases, into adenosquamous or squamous carcinoma, bronchioloalveolar carcinoma,and carcinoid tumor. There are few reports in the international literature describing lung cancer metastasis to visceral organs in cats, especially with regard to squamous tumors. This report describes the clinical pathological, histological, andimmunohistochemical findings of lung squamous cell carcinoma with metastasis to small intestine in a cat.Case: A female, Siamese, unneutered, adult cat presented with an unhealed ulcerative crusted lesion on the left ear, previously diagnosed as squamous cell carcinoma (SCC). Six months later, the cat returned presenting with increased volumein the left pelvic limb and claudication due to severe osteolysis in metatarsal and tarsal bones, as shown in radiographicexaminations. The limb was amputated forty day later, but it did not undergo histological examination. The cat died fourteendays after amputation and underwent necropsy. Macroscopically, significant changes were observed in the small intestine,including serous segmental necrotizing and hemorrhagic lesion with luminal stenosis and corrugation of mucous surface,which was covered with a fibrinopurulent pseudomembrane. Palpation of lung parenchyma showed small firm nodules.There was an ulcerative crusted lesion on the left ear. Histopatological examination revealed infiltration of pleomorphicneoplastic epithelial cells disrupting the architecture of small intestine and lung, with pronounced anisocyitosis and anisokaryosis. The neoplastic cells had indistinct borders; their cytoplasm was eosinophilic and pleomorphic and varied frommoderate to abundant in amount; and their nuclei...