RESUMO

This study was aimed at investigating the anti-osteoporotic effects of the extract of Ginkgo biloba (EGb) in glucocorticoid-induced-osteoporosis. A significant reduction was observed in the percentage of the bone of the osteoporosis group in both the mandible and femur. The EGb group treated with 28 and 56 mg/Kg showed a significant increase in the percentage of trabecular bone (PTB) of the femur. The percentage of the alveolar bone of the mandible (PAB) had a significant increase with all doses of EGb. The treatment with EGb significantly reversed the loss of the PAB of the mandible and of the PTB of the femur.

Assuntos

Densidade Óssea/efeitos dos fármacos , Ginkgo biloba/química , Osteoporose/tratamento farmacológico , Fitoterapia , Extratos Vegetais/farmacologia , Animais , Dexametasona/análogos & derivados , Dexametasona/toxicidade , Feminino , Fêmur , Mandíbula , Osteoporose/induzido quimicamente , Extratos Vegetais/química , Distribuição Aleatória , Ratos , Ratos Wistar