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BACKGROUND: Chronic lymphedema is a progressive and inflammatory disease caused by impaired lymphatic transport. PURPOSE: This study evaluates the effects of complex decongestive therapy (CDT) and aquatic physiotherapy on markers of the inflammatory process and lower limb volumes in individuals with lymphedema. METHODS: A randomized controlled clinical trial was carried out with three groups: patients with lymphedema submitted to CDT, patients with lymphedema submitted to aquatic physiotherapy, and control group of individuals without lymphedema. The evaluation was performed through blood count, CRP measurements, C3, C4 complement, measurement of serum levels of cytokines interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), interleukins 4 (IL-4), 6 (IL-6), and 10 (IL-10), and the volume of a lower limb using the volume formula of a truncated cone. The study was registered with the Brazilian Clinical Trials Registry (RBR-4tpkszn). RESULTS: Our work showed a reduction in the TNF-α levels of patients in the CDT group (p = .028). Significant differences were found between the control group and the CDT group for IL-10 (p = .049) and Monocytes (p = .039). No significant reduction in limb volume was found. CONCLUSION: Our results show that CDT was able to significantly reduce the inflammatory marker TNF-α in patients with lymphedema, suggesting an anti-inflammatory effect of the therapy.

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This is a quasi-randomised clinical trial, with 62 low-risk pregnant women in the second stage of labour. They were randomly allocated in control (CG) (n = 31) and intervention (IG) (n = 31) groups. The IG performed spontaneous pushing with pursed lips breathing while the CG was oriented to perform directed pushing associated with Valsalva Manoeuvre (VM). There was no difference between the groups regarding the occurrence of episiotomy (RR 1,1; 95%IC 1,0 to 1,2). However, there was a decrease in the duration of the maternal pushing by 3.2 min (MD 3,2; 95%CI 1,4 to 5,1) and a difference in maternal anxiety (Md (IQR) IG 46 (35-52), CG 51 (44-56) p:0,049), both favouring the IG. Spontaneous pushing was effective in reducing the duration of the pushing and showed a difference in maternal anxiety but did not decrease the maternal and neonatal outcomes. Brazilian Clinical Trials Registry (ReBEC) under the identifier: RBR-556d22IMPACT STATEMENTWhat is already known on the subject? Spontaneous pushing reduces the duration of pushing time when compared to directed pushing with VM but has no effect on other maternal and neonatal outcomes, based on a low quality of evidence.What do the results of this study add? No subject has been published on the subject. Our results suggest that the use spontaneous pushing with pursed lips breathing reduces the duration of the pushing by 3.2 min, also showing a difference in maternal anxiety. This result may indicate its use for emotional control when compared to the directed pushing.What are the implications of these findings for clinical practice and/or further research? These findings may signal an attitude in decision-making about guiding the breathing pattern in the expulsive stage.

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BACKGROUND: Low back pain during pregnancy is very common and thermography seems to be a promising method of evaluation for pregnant women, because it is painless and safe. The aim of the present study was to evaluate low back pain, during pregnancy, using thermography together with artificial intelligence. METHODS: A cross-sectional study was carried out with pregnant women recruited from a university hospital. The following data were collected: (a) clinical data; (b) physical assessment with mobility and low back pain provocation tests; and (c) thermograms acquisitions, in a controlled environment. Artificial intelligence and the statistical tests were used to compare the groups' mean: with low back pain (LBP) and without low back pain (WLBP). RESULTS: Thirty pregnant women took part, with fifteen in each group. The mean ± Standard Deviation temperature of the lumbar region in both groups were 32.7 ± 1.05 °C and 32.6 ± 1.01 °C for LBP and WLBP, respectively. There was not any difference in temperature between the groups; however, the artificial intelligence software found thermogram differences between groups; furthermore, the correlation between pain intensity and functionality was found. CONCLUSION: Thermography associated with artificial intelligence analyses demonstrated to be a promising method as an adjunct to clinical evaluation.

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OBJETIVO: Avaliar a sensibilidade de áreas que receberam enxerto de pele nos membros superiores de pacientes queimados e sua percepção de como a sensibilidade está relacionada à sua qualidade de vida. MÉTODO: Foram avaliados 30 indivíduos, com queimadura em membro superior, tratados com enxertia. Foram obtidos dados pessoais e histórico da lesão. Aplicava-se a escala de Vancouver para avaliar a sensibilidade da área enxertada e a mesma era medida. A sensibilidade tátil foi avaliada por meio de um estesiômetro, já a sensibilidade térmica foi avaliada por meio de um tubo de ensaio com água a 40°C, com água temperatura ambiente e aplicava-se gelo. Por meio da utilização do TENS, no modo convencional e com variação de intensidade e frequência (VIF), avaliou-se a sensação de prurido e sensibilidade nociceptiva, respectivamente. A qualidade de vida foi avaliada através do BSHS-R. RESULTADOS E CONCLUSÃO: Queimaduras nos membros superiores tratadas com enxerto de pele precisam de estímulos de intensidades maiores para despertar sensação nas áreas queimadas quando comparadas às sadias. A sensibilidade térmica tende a retornar mais rápido. As alterações da sensibilidade na área do enxerto interferem na qualidade de vida do paciente.

OBJECTIVE: To evaluate the sensitivity of areas that received skin grafts on the upper limbs of burned patients and their perception of how the sensitivity is related to their quality of life. METHODS: Thirty individuals with burns on the upper limbs, treated with grafting, were evaluated. Personal data and history of the injury were obtained. The Vancouver scale was applied to assess the sensitivity of the grafted area and it was measured. The tactile sensitivity was assessed by means of a stoichiometer, whereas the thermal sensitivity was assessed by means of a test tube with water at 40°C, with water at room temperature and ice was applied. Through the use of TENS, in the conventional way and with varying intensity and frequency (VIF), itching sensation and nociceptive sensitivity were evaluated, respectively. Quality of life was assessed using the BSHS-R. RESULTS AND CONCLUSION: Burns in the upper limbs treated with a skin graft need stimuli of greater intensity to arouse sensations when compared to healthy areas. Thermal sensitivity tends to return faster. Sensitivity changes in the graft area interfere with patients quality of life.

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RESUMO Objetivou-se avaliar alterações imunes, entre obesidade e exercício (natação). Ratas Wistar foram alocadas, conforme regime dietético: Grupo Labina (GL) e Grupo Hiperlipídico (GH); e, aos 60 dias, segundo o exercício. Após protocolo de exercício, avaliaram-se parâmetros murinométricos, gordura visceral, série branca do sangue e cultura de macrófagos. Observamos aumento nos parâmetros murinométricos, na gordura visceral do GH sedentário e nos linfócitos, neutrófilos e basófilos do GH exercitado. A taxa de fagocitose e a produção de óxido nítrico estimulado com lipopolissacarídeos aumentaram nos ratos exercitados. A natação parece reverter o fenótipo de sobrepeso, promovido pela dieta hiperlipídica, atenuou os efeitos dessa no sistema imune e melhorou sua resposta.

ABSTRACT The aim was to evaluate immune changes between obesity and swimming. Wistar rats were allocated according to dietary regimen: Labina Group (LG) and Hyperlipid Group (HG); and at 60 days, according to the exercise. After exercise protocol, murinometric parameters, visceral fat, white blood series and macrophage culture were evaluated. We observed an increase in the murinometric parameters and visceral fat of the sedentary HG, and in the lymphocytes, neutrophils and basophils of the exercised HG. The rate of phagocytosis and the production of nitric oxide stimulated with lipopolysaccharides increased in the exercised rats. Swimming seems to reverse the overweight phenotype promoted by the hyperlipid diet and attenuated the effects it on the immune system, improving its response.

RESUMEN El objetivo de este artículo fue evaluar cambios inmunológicos entre obesidad y ejercicio (natación). Se distribuyó a ratas Wistar según el régimen dietético: grupo labina (GL) y grupo hiperlipídico (GH). Y a los 60 días, según el ejercicio. Después del protocolo de ejercicio, se evaluaron los parámetros murinométricos, grasa visceral, serie blanca de la sangre y cultivo de macrófagos. Se observó un aumento de los parámetros murinométricos y de la grasa visceral del GH sedentario, así como en los linfocitos, neutrófilos y basófilos del GH ejercitado. La tasa de fagocitosis y la producción de óxido nítrico estimulado con lipopolisacárido aumentaron en las ratas ejercitadas. Parece que la natación revierte el fenotipo de sobrepeso promovido por la dieta hiperlipídica y atenúa los efectos de esta en el sistema inmunitario, por lo que mejora su respuesta.

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BACKGROUND: Lymphedema of the lower limbs is a chronic disease caused by damage to the lymphatic system that influences people's mobility, functionality, and quality of life. Questionnaires and physical test are very practical, easy to apply, and low cost methods that provide important data for evaluation of these patients. OBJECTIVES: To evaluate the influence of unilateral lower limb lymphedema on functionality and quality of life, correlating 3 assessment tools. METHODS: This was a descriptive study investigating 25 patients of both sexes with unilateral lymphedema in a lower limb. Limb volume was assessed using circumferential tape measurements, the Medical Outcomes Study Short Form-36 Health Survey (SF-36) was used to assess quality of life, the Lymphoedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph-ICF-LL) was used to assess physical, mental, and social skills related to lymphedema, and the Timed Up and Go (TUG) test was used for functional assessment. RESULTS: Lymphedema was present throughout the affected lower limb of participants. The domains most affected by lymphedema were physical aspects (25.0 ± 31.4) and emotional aspects (36.0 ± 42.9) from the SF-36 and the mobility domain (6.0 ± 2.6) from the Lymph -ICF-LL. Patients performed the TUG in 9.88 ± 1.98 seconds. The TUG was correlated with the questionnaires and the questionnaires were correlated with each other. CONCLUSIONS: People with unilateral lower limb lymphedema exhibited negative impacts on quality of life and functionality, as evaluated by questionnaires, which were correlated with each other. TUG performance was within normal limits, but results correlated with the questionnaires used.

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OBJECTIVE: To evaluate the impact of lipoabdominoplasty on diaphragmatic mobility (DM) and lung function in healthy women. METHODS: This was a prospective cohort study using high-resolution ultrasound and forced spirometry to assess DM and lung function, respectively, prior to lipoabdominoplasty, as well as on postoperative day (POD) 10 and POD 30. DM was measured under two conditions: during tidal volume breathing and during a VC maneuver. RESULTS: The sample consisted of 20 women, with a mean age of 39.85 ± 7.52 years and a mean body mass index of 26.21 ± 2.0 kg/m2. Comparing the preoperative and postoperative periods, we found that DM and lung function values were significantly lower after lipoabdominoplasty, the mean DM on POD 10 being 17% and 15% lower during tidal volume breathing and during the VC maneuver, respectively, in comparison with the preoperative mean (p = 0.009 and p < 0.001, respectively). In addition, FEV1, FVC, and PEF were significantly lower on POD 10 than in the preoperative period (p = 0.046, p = 0.002, and p < 0.001, respectively), returning to preoperative values by POD 30. CONCLUSIONS: Lipoabdominoplasty appears to have negative short-term repercussions for DM and lung function in healthy women. However, lung function and DM are both apparently restored to preoperative conditions by POD 30. (ClinicalTrials.gov identifier: NCT02762526 [http://www.clinicaltrials.gov/]).

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ABSTRACT Objectives: To qualitatively and quantitatively analyze the interaction of Russian and Aussie currents in isometric contraction of the quadriceps femoris muscle in the sensory, motor and pain tolerance spectra in healthy young women. Methods: The subjects were studied at a single point in time. A lower limb was selected at random to receive each current, and the electrodes were placed simultaneously on both legs, respecting 10 minutes between individual stimulation. Sensory, motor and pain-tolerance thresholds were assessed in quantitative (current density in mA/cm²) and qualitative (VAS) terms. Results: Subjects were 19 volunteers, aged 22.31 (1.29), with a BMI of 21.79 (1.78). The Aussie current reached the sensory threshold with significantly lower current density when compared with the Russian current for the same threshold. The results were significant in the overall group (treatment) for the two currents studied in terms of current density needed to reach the three thresholds. However, in the blocks (individually), there was significance only for the sensory threshold (p = 0.0126). Analysis of the perception of discomfort, assessed by VAS, was significant at the three time points for both currents, but in the comparison between these there was no significant difference. Conclusion: The Russian and Aussie currents are adequate in terms of the current density required to reach each threshold studied, and present differences between one another during interaction with the biological system, with the Aussie current necessitating less energy. However, in terms of perception of discomfort there are no significant differences between the two currents. Level of evidence III; Therapeutic studies - Investigating the results of treatment.

RESUMO Objetivos: Analisar qualitativa e quantitativamente a interação das correntes Russa e Aussie na contração isométrica do músculo quadríceps femoral, nos no âmbito sensitivo, motor e de desconforto em mulheres jovens saudáveis. Métodos: As voluntárias foram analisadas em um único momento. Sorteou-se qual membro inferior receberia cada corrente e os eletrodos foram posicionados simultaneamente nos dois membros inferiores, respeitando-se 10 minutos entre a estimulação de cada um. Foram avaliados os limiares sensitivo, motor e de desconforto em termos quantitativos (densidade de corrente em mA/cm²) e qualitativos (EVA). Resultados: Participaram 19 voluntárias, na faixa etária de 22,31 (1,29) e IMC de 21,79 (1,78). A corrente Aussie alcançou o limiar sensitivo com menor densidade de corrente de forma significativa com relação à Russa para o mesmo limiar. Os resultados foram significativos no grupo geral (tratamento) para as duas correntes estudadas quanto à densidade de corrente necessária para atingir os três limiares. Já nos blocos (individualmente), houve significância apenas para o limiar sensitivo (p=0,0126). A análise da percepção de desconforto, avaliada através da EVA, foi significativa nos três momentos para ambas as correntes, mas na comparação entre elas não houve diferença significativa. Conclusão: As correntes Russa e Aussie são adequadas quanto à densidade de corrente necessária para atingir cada limiar estudado e apresentam diferenças entre si durante a interação com o sistema biológico, necessitando a Aussie de menos energia. No entanto, em termos de percepção de desconforto não há diferenças significativas entre as duas correntes. Nível de evidência III; Estudos terapêuticos-Investigação dos resultados do tratamento.

RESUMEN Objetivos: Analizar cualitativa y cuantitativamente la interacción de las corrientes Rusa y Aussie, en la contracción isométrica del músculo cuádriceps femoral, en el ámbito sensitivo, motor y de incomodidad en mujeres jóvenes sanas. Métodos: Las voluntarias se analizaron en un solo momento. Se sorteó cuál miembro inferior recibiría cada corriente y los electrodos fueron colocados simultáneamente en los dos miembros inferiores, respetándose 10 minutos entre la estimulación de cada uno. Se evaluaron los umbrales sensitivo, motor y de incomodidad en términos cuantitativos (densidad de corriente en mA/cm²) y cualitativos (EVA). Resultados: Participaron 19 voluntarias, en el grupo de edad de 22,31 (1,29) e IMC de 21,79 (1,78). La corriente Aussie alcanzó el umbral sensitivo con menor densidad de corriente de forma significativa con respecto a la rusa para el mismo umbral. Los resultados fueron significativos en el grupo general (tratamiento) para las dos corrientes estudiadas en cuanto a la densidad de corriente necesaria para alcanzar los tres umbrales. En los bloques (individualmente), hubo significancia sólo para el umbral sensitivo (p = 0,0126). El análisis de la percepción de incomodidad, evaluada a través de la EVA, fue significativo en los tres momentos para ambas corrientes, pero en la comparación entre ellas no hubo diferencia significativa. Conclusión: Las corrientes Rusa y Aussie son adecuadas en cuanto a la densidad de corriente necesaria para alcanzar cada umbral estudiado y presentan diferencias entre sí durante la interacción con el sistema biológico, necesitando la Aussie de menos energía. Sin embargo, en términos de percepción de incomodidad no hay diferencias significativas entre las dos corrientes. Nivel de evidencia III; Estudios terapéuticos-Investigación de los resultados del tratamiento.

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O linfedema de membros inferiores é uma doença crônica decorrente de dano no sistema linfático que influencia a mobilidade, a funcionalidade e a qualidade de vida dos indivíduos. Questionários e o teste físico são métodos bastante práticos, de fácil aplicação e baixo custo, que fornecem dados importantes para a avaliação desses pacientes. Objetivos Avaliar a influência do linfedema unilateral de membro inferior na funcionalidade e na qualidade de vida, correlacionando três ferramentas de avaliação. Métodos Estudo descritivo com 25 indivíduos com linfedema unilateral em membro inferior, de ambos os sexos. Foi avaliada a perimetria e foram aplicados The Medical Outcome Study Short Form-36 Health Survey (SF-36) para avaliação da qualidade de vida, Lymphoedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph-ICF-LL) para estudo das habilidades físicas, mentais e sociais relacionadas ao linfedema e o Timed Up and Go (TUG) para avaliação da funcionalidade. Resultados Houve a presença de linfedema em todo o membro inferior dos participantes. Os domínios mais prejudicados pelo linfedema foram os aspectos físicos (25,0 ± 31,4) e emocionais (36,0 ± 42,9) no SF-36 e o domínio mobilidade (6,0 ± 2,6) no Lymph-ICF-LL. O TUG foi realizado em 9,88 ± 1,98 s. Houve correlação entre o TUG e os questionários e entre os dois questionários utilizados. Conclusões Indivíduos com linfedema unilateral em membro inferior apresentam um impacto negativo na qualidade de vida e na funcionalidade avaliadas através de questionários, que correlacionam entre si. Não foi encontrada alteração no TUG, mas houve correlação entre ele e os questionários utilizados

Lymphedema of the lower limbs is a chronic disease caused by damage to the lymphatic system that influences people's mobility, functionality, and quality of life. Questionnaires and physical test are very practical, easy to apply, and low cost methods that provide important data for evaluation of these patients. Objectives To evaluate the influence of unilateral lower limb lymphedema on functionality and quality of life, correlating 3 assessment tools. Methods This was a descriptive study investigating 25 patients of both sexes with unilateral lymphedema in a lower limb. Limb volume was assessed using circumferential tape measurements, the Medical Outcomes Study Short Form-36 Health Survey (SF-36) was used to assess quality of life, the Lymphoedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph-ICF-LL) was used to assess physical, mental, and social skills related to lymphedema, and the Timed Up and Go (TUG) test was used for functional assessment. Results Lymphedema was present throughout the affected lower limb of participants. The domains most affected by lymphedema were physical aspects (25.0 ± 31.4) and emotional aspects (36.0 ± 42.9) from the SF-36 and the mobility domain (6.0 ± 2.6) from the Lymph -ICF-LL. Patients performed the TUG in 9.88 ± 1.98 seconds. The TUG was correlated with the questionnaires and the questionnaires were correlated with each other. Conclusions People with unilateral lower limb lymphedema exhibited negative impacts on quality of life and functionality, as evaluated by questionnaires, which were correlated with each other. TUG performance was within normal limits, but results correlated with the questionnaires used

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ABSTRACT Objective: To evaluate the impact of lipoabdominoplasty on diaphragmatic mobility (DM) and lung function in healthy women. Methods: This was a prospective cohort study using high-resolution ultrasound and forced spirometry to assess DM and lung function, respectively, prior to lipoabdominoplasty, as well as on postoperative day (POD) 10 and POD 30. DM was measured under two conditions: during tidal volume breathing and during a VC maneuver. Results: The sample consisted of 20 women, with a mean age of 39.85 ± 7.52 years and a mean body mass index of 26.21 ± 2.0 kg/m2. Comparing the preoperative and postoperative periods, we found that DM and lung function values were significantly lower after lipoabdominoplasty, the mean DM on POD 10 being 17% and 15% lower during tidal volume breathing and during the VC maneuver, respectively, in comparison with the preoperative mean (p = 0.009 and p < 0.001, respectively). In addition, FEV1, FVC, and PEF were significantly lower on POD 10 than in the preoperative period (p = 0.046, p = 0.002, and p < 0.001, respectively), returning to preoperative values by POD 30. Conclusions: Lipoabdominoplasty appears to have negative short-term repercussions for DM and lung function in healthy women. However, lung function and DM are both apparently restored to preoperative conditions by POD 30. (ClinicalTrials.gov identifier: NCT02762526 [http://www.clinicaltrials.gov/])

RESUMO Objetivo: Avaliar o impacto da lipoabdominoplastia na mobilidade diafragmática (MD) e na função pulmonar de mulheres saudáveis. Métodos: Estudo prospectivo de coorte com ultrassonografia de alta resolução e espirometria forçada para a avaliação da MD e da função pulmonar, respectivamente, antes da lipoabdominoplastia, no 10º dia do pós-operatório e no 30º dia do pós-operatório. A MD foi medida durante a respiração em volume corrente e durante uma manobra de CV. Resultados: A amostra foi composta por 20 mulheres, com média de idade de 39,85 ± 7,52 anos e média de índice de massa corporal de 26,21 ± 2,0 kg/m2. Ao compararmos os períodos pré e pós-operatório, observamos que a MD e a função pulmonar foram significativamente menores após a lipoabdominoplastia; a média de MD no 10º dia do pós-operatório foi 17% menor durante a respiração em volume corrente e 15% menor durante a manobra de CV do que a média pré-operatória (p = 0,009 e p < 0,001, respectivamente). Além disso, o VEF1, a CVF e o PFE foram significativamente menores no 10º dia do pós-operatório que no pré-operatório (p = 0,046, p = 0,002 e p < 0,001, respectivamente), retornando aos valores pré-operatórios até o 30º dia do pós-operatório. Conclusões: A lipoabdominoplastia parece ter repercussões negativas em curto prazo na MD e função pulmonar de mulheres saudáveis. No entanto, tanto a função pulmonar como a MD aparentemente retornam ao estado pré-operatório até o 30º dia do pós-operatório. (ClinicalTrials.gov identifier: NCT02762526 [http://www.clinicaltrials.gov/])

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