RESUMO
Feline leishmanial infection is reported worldwide, but the epidemiological role of domestic cats in the leishmaniasis cycle remains unclear, and cats might act as cryptic reservoir hosts in endemic areas with no feline leishmaniosis cases. Considering that, a serological screening for anti-Leishmania spp. antibodies was performed by indirect immunofluorescence antibody test (IFAT) in 389 necropsied cats' serum samples from a new visceral leishmaniasis transmission area with no feline leishmanial infection reported to unveil if the cats are being exposed to the parasite. The overall seroprevalence for Leishmania spp. was 11.05% (43/389). No association was found between sex, neutering status, age group, breed, coat length, feline immunodeficiency virus (FIV) infection, and Leishmania spp. antibody detection. A positive association was found with coat color (cats within the orange spectrum with white [particolor]) (OR = 2.47, CI 95% 1 - 6.13, P = 0.044) and a negative association (OR = 0.38, CI 95% 0.18 - 0.79, P = 0.01) between feline leukemia virus (FeLV) infection and IFAT positivity for Leishmania spp. Therefore, it is concluded that the seroprevalence found was greater than 10%, indicating contact of the protozoan with cats in the region served.
Assuntos
Doenças do Gato , Vírus da Imunodeficiência Felina , Leishmania infantum , Leishmaniose Visceral , Leishmaniose , Leucemia Felina , Animais , Gatos , Leishmaniose Visceral/diagnóstico , Leishmaniose Visceral/epidemiologia , Leishmaniose Visceral/veterinária , Estudos Soroepidemiológicos , Leishmaniose/epidemiologia , Leishmaniose/veterinária , Leucemia Felina/epidemiologia , Anticorpos Antiprotozoários , Doenças do Gato/diagnóstico , Doenças do Gato/epidemiologia , Vírus da Leucemia FelinaRESUMO
In Brazil, visceral leishmaniasis (VL) has been expanding and urbanizing, mainly in non-endemic areas such as the State of Rio Grande do Sul. Considering that infected dogs are the main reservoirs of VL in urban areas, the present study aimed to evaluate the propagation of canine visceral leishmaniasis (CVL) infection from an unaffected region in transition to a VL transmission area. For this, 1159 and 1087 samples of canine serum from 2015 and 2021, respectively, were analyzed, using the indirect immunofluorescence test. In addition, necropsy reports between 2007 and 2021 were evaluated. The results showed a prevalence of anti-Leishmania spp. antibodies of 7.5% in the samples from 2015, while in 2021 samples, it was 23.5%, with an incidence of 0.4 cases per 100 dogs. It is noteworthy that in 2007, there was no record of CVL as the cause of death in the pathological reports, and in 2021, 41 diagnoses were made with the protozoan being a determinant of the death of the animal. These values indicate an increasing trend in the prevalence and incidence coefficients of CVL. The results of this study allowed us to verify the spread of the disease from an unaffected region to a transmission area of the agent, as well as provide subsidies for health authorities to implement improvements in the CVL control program in the municipality, to mitigate the emergence of human cases of the disease.
Assuntos
Doenças do Cão , Leishmania infantum , Leishmania , Leishmaniose Visceral , Leishmaniose , Animais , Brasil/epidemiologia , Doenças do Cão/diagnóstico , Cães , Humanos , Leishmaniose Visceral/diagnóstico , Leishmaniose Visceral/epidemiologia , Leishmaniose Visceral/veterináriaRESUMO
ABSTRACT: Epidermoid cysts, also known as epidermal and keratin cysts, or congenital cholesteatomas are benign congenital non-neoplastic tumors, rarely observed in the brain of humans and some animal species (dogs, horses, mice, and rats). Histologically, they are composed of laminated, concentrically arranged keratin surrounded by a thin layer of stratified squamous epithelium. We describe a case of intracranial epidermoid cyst in a 6-year-old mixed-breed male cat in southern Brazil. The patient presented central vestibular syndrome. Given the poor prognosis and the fact that it belonged to a shelter with many dogs and cats, the owner requested euthanasia, and a thorough post-mortem examination was conducted immediately after death. The definitive diagnosis was based on histopathological findings. To the best of our knowledge, this is the first report of an intracranial epidermoid cyst in a cat.
RESUMO: Cisto epidermoide, também denominado cisto epidermal, cisto de queratina ou colesteatoma congênito é um tumor não neoplásico, benigno e congênito raramente encontrado no encéfalo de humanos e de algumas poucas espécies animais (cães, equinos, camundongos e ratos). Histologicamente, esse tumor é composto por queratina laminada concentricamente arranjada e circundada por uma fina parede de epitélio escamoso estratificado. Descreve-se um caso de cisto epidermoide intracraniano em um gato, macho, sem raça definida, de seis anos de idade, no sul do Brasil. O paciente foi encaminhado para atendimento veterinário por apresentar sinais de síndrome vestibular central. Devido ao mau prognóstico e por pertencer a um abrigo com muitos cães e gatos, o proprietário optou pela eutanásia e o paciente foi encaminhado para a realização de necropsia. O diagnóstico definitivo foi baseado nos achados histopatológicos. Pelo conhecimento dos autores, este é o primeiro relato de um cisto epidermoide intracraniano em um gato.
RESUMO
Epidermoid cysts, also known as epidermal and keratin cysts, or congenital cholesteatomas are benign congenital non-neoplastic tumors, rarely observed in the brain of humans and some animal species (dogs, horses, mice, and rats). Histologically, they are composed of laminated, concentrically arranged keratin surrounded by a thin layer of stratified squamous epithelium. We describe a case of intracranial epidermoid cyst in a 6-year-old mixed-breed male cat in southern Brazil. The patient presented central vestibular syndrome. Given the poor prognosis and the fact that it belonged to a shelter with many dogs and cats, the owner requested euthanasia, and a thorough post-mortem examination was conducted immediately after death. The definitive diagnosis was based on histopathological findings. To the best of our knowledge, this is the first report of an intracranial epidermoid cyst in a cat.(AU)
Cisto epidermoide, também denominado cisto epidermal, cisto de queratina ou colesteatoma congênito é um tumor não neoplásico, benigno e congênito raramente encontrado no encéfalo de humanos e de algumas poucas espécies animais (cães, equinos, camundongos e ratos). Histologicamente, esse tumor é composto por queratina laminada concentricamente arranjada e circundada por uma fina parede de epitélio escamoso estratificado. Descreve-se um caso de cisto epidermoide intracraniano em um gato, macho, sem raça definida, de seis anos de idade, no sul do Brasil. O paciente foi encaminhado para atendimento veterinário por apresentar sinais de síndrome vestibular central. Devido ao mau prognóstico e por pertencer a um abrigo com muitos cães e gatos, o proprietário optou pela eutanásia e o paciente foi encaminhado para a realização de necropsia. O diagnóstico definitivo foi baseado nos achados histopatológicos. Pelo conhecimento dos autores, este é o primeiro relato de um cisto epidermoide intracraniano em um gato.(AU)
Assuntos
Animais , Masculino , Gatos , Colesteatoma/congênito , Colesteatoma/diagnóstico , Colesteatoma/veterinária , Cisto Epidérmico/diagnóstico , Cisto Epidérmico/veterinária , Gatos/anormalidades , Gatos/lesõesRESUMO
O linfoma é um dos tipos de câncer mais prevalentes em cães, no entanto, aspectos macroscópicos, de lesões superficiais eritematosas e esfoliativas a tumores. é incomum na pele. Quando se origina na pele, tem sido observado sob vários Histologicamente, os linfomas cutâneos são subdivididos em epiteliotrópicos. Os linfomas epiteliotrópicos geralmente são vistos como micose fungoide e, mais raramente, como reticulose pagetoide ou síndrome de Sézary. Os linfomas não epiteliotrópicos incluem: linfoma anaplásico de grandes células T, linfoma de células T periféricas inespecífico, granulomatose linfomatoide, linfoma intravascular e linfoma de células T semelhante a paniculite subcutânea. Esta revisão de literatura apresenta os aspectos macroscópicos e histopatológicos dos linfomas cutâneos caninos.
Lymphoma is one of the most prevalent forms of cancers in dogs, however, it is uncommon on the skin. Cutaneous lymphoma can present as erythematous and exfoliative superficial lesions or raised masses. Histologically, cutaneous lymphomas are subdivided into epitheliotropic and non-epitheliotropic. Epitheliotropic lymphomas is mostly seen as mycosis fungoides and more rarely as pagetoid reticulosis or Sézary syndrome. Non-epitheliotropic lymphomas include anaplastic large T-cell lymphoma, unspecified peripheral T-cell lymphoma, lymphomatoid granulomatosis, intravascular lymphoma, and subcutaneous panniculitis-like T-cell lymphoma. This literature review presents macroscopic and histopathological aspects of canine cutaneous lymphomas.
El linfoma representa uno de los tipos de cáncer más prevalentes en perros, si bien su manifestación dérmica es poco frecuente. Los linfomas de piel pueden presentarse como lesiones superficiales eritematosas y exfoliativas, o bien como tumores. Desde el punto de vista histológico pueden ser clasificados como epiteliotrópicos y no epiteliotrópicos. Los primeros suelen ser vistos como micosis fúngica y, más raro, como reticulosis pagetoide o Síndrome de Sézary. Los linfomas no epiteliotrópicos incluyen el linfoma anaplásico de células T gigantes, linfoma inespecífico de células T, granulomatosis linfomatoide, linfoma intravascular y linfoma de células T similar a paniculitis subcutánea. Esta revisión de literatura presenta aspectos macroscópicos e histopatológicos de los linfomas cutáneos del perro.
Assuntos
Animais , Cães , Cães/anatomia & histologia , Cães/lesões , Linfoma , Linfócitos TRESUMO
O linfoma é um dos tipos de câncer mais prevalentes em cães, no entanto, aspectos macroscópicos, de lesões superficiais eritematosas e esfoliativas a tumores. é incomum na pele. Quando se origina na pele, tem sido observado sob vários Histologicamente, os linfomas cutâneos são subdivididos em epiteliotrópicos. Os linfomas epiteliotrópicos geralmente são vistos como micose fungoide e, mais raramente, como reticulose pagetoide ou síndrome de Sézary. Os linfomas não epiteliotrópicos incluem: linfoma anaplásico de grandes células T, linfoma de células T periféricas inespecífico, granulomatose linfomatoide, linfoma intravascular e linfoma de células T semelhante a paniculite subcutânea. Esta revisão de literatura apresenta os aspectos macroscópicos e histopatológicos dos linfomas cutâneos caninos.(AU)
Lymphoma is one of the most prevalent forms of cancers in dogs, however, it is uncommon on the skin. Cutaneous lymphoma can present as erythematous and exfoliative superficial lesions or raised masses. Histologically, cutaneous lymphomas are subdivided into epitheliotropic and non-epitheliotropic. Epitheliotropic lymphomas is mostly seen as mycosis fungoides and more rarely as pagetoid reticulosis or Sézary syndrome. Non-epitheliotropic lymphomas include anaplastic large T-cell lymphoma, unspecified peripheral T-cell lymphoma, lymphomatoid granulomatosis, intravascular lymphoma, and subcutaneous panniculitis-like T-cell lymphoma. This literature review presents macroscopic and histopathological aspects of canine cutaneous lymphomas.(AU)
El linfoma representa uno de los tipos de cáncer más prevalentes en perros, si bien su manifestación dérmica es poco frecuente. Los linfomas de piel pueden presentarse como lesiones superficiales eritematosas y exfoliativas, o bien como tumores. Desde el punto de vista histológico pueden ser clasificados como epiteliotrópicos y no epiteliotrópicos. Los primeros suelen ser vistos como micosis fúngica y, más raro, como reticulosis pagetoide o Síndrome de Sézary. Los linfomas no epiteliotrópicos incluyen el linfoma anaplásico de células T gigantes, linfoma inespecífico de células T, granulomatosis linfomatoide, linfoma intravascular y linfoma de células T similar a paniculitis subcutánea. Esta revisión de literatura presenta aspectos macroscópicos e histopatológicos de los linfomas cutáneos del perro.(AU)
Assuntos
Animais , Cães , Cães/anatomia & histologia , Linfoma , Cães/lesões , Linfócitos TRESUMO
Background: Copper is an essential micronutrient for the body to function properly. However, although it is a vital element,an excess of copper in the body is extremely toxic. Copper toxicity has been reported mainly in sheep. In dogs, clinicopathological signs of toxicity are characterized by chronic liver failure. This means that the hemolytic crisis so commonin sheep is a condition rarely associated with toxicity in dogs, so there are very few descriptions of this condition in theveterinary literature. The purpose of this report is to describe a case of hemolytic crisis in a dog with copper-associatedchronic hepatitis.Case: A medium-sized 6-year-old bitch was brought to the Veterinary Hospital of the Federal University of Santa Maria,with clinical presentation of apathy, anorexia and red urine. A physical examination revealed mildly jaundiced mucosaand dark brown urine. A urinalysis indicated the presence of protein, bilirubin and occult blood. The blood count revealedhypochromic macrocytic anemia, leukocytosis due to left shift neutrophilia and thrombocytopenia. Serum biochemistryshowed elevated levels of alanine aminotransferase and alkaline phosphatase. The animal was given a blood transfusiondue to the severity of her anemia, but her clinical condition worsened and she died, whereupon her body was sent for necropsy. This necropsy revealed conspicuous signs of jaundice, splenomegaly and altered liver and kidney color. The liverwas brownish, with its natural surface firm and slightly irregular. The kidneys were diffusely blackened. The urine wasdark brown. Fragments of different organs were collected, fixed in 10% buffered formalin solution, routinely processedfor histopathology and stained with hematoxylin and eosin. A histological dissection of the liver showed the hepatic lobesdissected by fibrosis, forming islands of hepatocytes and numerous lymphocytes and...(AU)
Assuntos
Animais , Feminino , Cães , Hepatite Crônica/veterinária , Cobre/toxicidade , Hemolíticos/análise , Intoxicação por Metais Pesados/veterinária , Doença Hepática Crônica Induzida por Substâncias e Drogas/veterináriaRESUMO
A 10-year-old male large mixed breed dog was presented with skin ulcers and fracture on the right hind limb caused by vehicle collision. Given required limb amputation, and as being a shelter senior dog, euthanasia was requested by the owner and a complete post-mortem examination was conducted immediately after death. Gross changes were consistent with marked bilateral nephromegaly. Histopathological examination of the kidneys revealed round cells filling blood vessels. Immunohistochemically, the round cells were positive for CD3 antibody. Based on these findings, in absence of involvement of the bone marrow and peripheral blood, and inexistence of primary extravascular masses, the tumor was classified as T-cell intravascular lymphoma. To the authors knowledge, this is the first report describing intravascular lymphoma involving the kidneys alone in a dog.(AU)
Um canino, macho, de 10 anos, sem raça definida (SRD), e grande porte, chegou para atendimento apresentando fratura em membro pélvico direito devido a atropelamento por veículo automotivo. Adicionalmente, foram observadas úlceras cutâneas ao nível da fratura. Devido à necessidade de amputação do membro e, por ser um cão idoso, o proprietário optou pela eutanásia, realizando-se necropsia imediatamente após a morte do paciente. Os achados macroscópicos foram consistentes com acentuada nefromegalia bilateral. A avaliação histopatológica dos rins revelou células redondas neoplásicas obliterando vasos sanguíneos. Imunohistoquimicamente, essas células foram positivas para CD3. Baseando-se nos achados histopatológicos, na ausência de envolvimento da medula óssea e do sangue periférico e, na inexistência de massas primárias extravasculares, o tumor foi classificado como linfoma intravascular de células T. Possivelmente, este é o primeiro relato de linfoma intravascular envolvendo unicamente os rins de um cão.(AU)
Assuntos
Animais , Cães , Linfoma/veterinária , Neoplasias Renais/veterinária , Neoplasias Vasculares/veterinária , Neoplasias Renais/ultraestrutura , Linfócitos T/patologiaRESUMO
Background: Melanocytic neoplasms are skin tumors that often occur in dogs. However, melanocytoma-acanthoma, alsocalled melanoacanthoma, is a benign melanocytic neoplasm rarely reported in this species, which has been described onlythree times in the veterinary literature. Briefly, this tumor is characterized by a single, painless, darkly pigmented and firmcutaneous papule or nodule. Histologically, it is composed of mixed populations of well-differentiated melanocytes andkeratinocytes, unlike traditional melanocytic tumors (melanoma and melanocytoma). These cells are arranged in lobulessurrounded by collagenous stroma. Melanocytes are large epithelioid cells containing varying amounts of melanin. Keratinocytes form anastomosing trabeculae with peripheral palisading, and small cysts containing amorphous or laminatedkeratin. The definitive diagnosis of melanocytoma-acanthoma is based on histopathological findings. This report describesa case of melanocytoma-acanthoma in a dog in Brazil.Case: A 9-year-old female miniature Schnauzer dog was examined at the Veterinary Hospital of the Federal Universityof Santa Maria, where a single, firm, pigmented papule was found in the auricle. The lesion had started 15 days earlier.Hematological tests and serum biochemistry profile were normal. An excisional biopsy of the papule was surgically removed and subjected to histopathological examination. The tissue was fixed in 10% neutral buffered formalin, processedroutinely and embedded in paraffin wax. Sections were stained with hematoxylin and eosin (HE). A histopathologicalexamination revealed a nonencapsulated, well-defined, extensive, densely cellular proliferation located in dermis. Thisproliferation was composed of lobules and nests of well-differentiated stratified squamous epithelium closely associatedwith neoplastic melanocytes, surrounded by thin bundles of fibrous stroma. A diagnosis of...(AU)
Assuntos
Animais , Cães , Melanócitos/patologia , Acantoma/veterinária , Neoplasias Cutâneas/veterináriaRESUMO
ABSTRACT: A 10-year-old male large mixed breed dog was presented with skin ulcers and fracture on the right hind limb caused by vehicle collision. Given required limb amputation, and as being a shelter senior dog, euthanasia was requested by the owner and a complete post-mortem examination was conducted immediately after death. Gross changes were consistent with marked bilateral nephromegaly. Histopathological examination of the kidneys revealed round cells filling blood vessels. Immunohistochemically, the round cells were positive for CD3 antibody. Based on these findings, in absence of involvement of the bone marrow and peripheral blood, and inexistence of primary extravascular masses, the tumor was classified as T-cell intravascular lymphoma. To the author's knowledge, this is the first report describing intravascular lymphoma involving the kidneys alone in a dog.
RESUMO: Um canino, macho, de 10 anos, sem raça definida (SRD), e grande porte, chegou para atendimento apresentando fratura em membro pélvico direito devido a atropelamento por veículo automotivo. Adicionalmente, foram observadas úlceras cutâneas ao nível da fratura. Devido à necessidade de amputação do membro e, por ser um cão idoso, o proprietário optou pela eutanásia, realizando-se necropsia imediatamente após a morte do paciente. Os achados macroscópicos foram consistentes com acentuada nefromegalia bilateral. A avaliação histopatológica dos rins revelou células redondas neoplásicas obliterando vasos sanguíneos. Imunohistoquimicamente, essas células foram positivas para CD3. Baseando-se nos achados histopatológicos, na ausência de envolvimento da medula óssea e do sangue periférico e, na inexistência de massas primárias extravasculares, o tumor foi classificado como linfoma intravascular de células T. Possivelmente, este é o primeiro relato de linfoma intravascular envolvendo unicamente os rins de um cão.