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J Pediatr ; 159(2): 256-61.e2, 2011 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21429515

RESUMO

OBJECTIVE: To determine whether pulmonary function decreases as a function of severity of pectus excavatum, and whether reduced function is restrictive or obstructive in nature in a large multicenter study. STUDY DESIGN: We evaluated preoperative spirometry data in 310 patients and lung volumes in 218 patients aged 6 to 21 years at 11 North American centers. We modeled the impact of the severity of deformity (based on the Haller index) on pulmonary function. RESULTS: The percentages of patients with abnormal forced vital capacity (FVC), forced expiratory volume in 1 second (FEV(1)), forced expiratory flow from 25% exhalation to 75% exhalation, and total lung capacity findings increased with increasing Haller index score. Less than 2% of patients demonstrated an obstructive pattern (FEV(1)/FVC <67%), and 14.5% demonstrated a restrictive pattern (FVC and FEV(1) <80% predicted; FEV(1)/FVC >80%). Patients with a Haller index of 7 are >4 times more likely to have an FVC of ≤80% than those with a Haller index of 4, and are also 4 times more likely to exhibit a restrictive pulmonary pattern. CONCLUSIONS: Among patients presenting for surgical repair of pectus excavatum, those with more severe deformities have a much higher likelihood of decreased pulmonary function with a restrictive pulmonary pattern.


Assuntos
Fluxo Expiratório Forçado/fisiologia , Tórax em Funil/diagnóstico , Insuficiência Respiratória/etiologia , Capacidade Vital/fisiologia , Adolescente , Criança , Progressão da Doença , Feminino , Seguimentos , Tórax em Funil/complicações , Tórax em Funil/fisiopatologia , Humanos , Masculino , Prognóstico , Estudos Prospectivos , Radiografia Torácica , Insuficiência Respiratória/diagnóstico , Insuficiência Respiratória/fisiopatologia , Índice de Gravidade de Doença , Espirometria , Tomografia Computadorizada por Raios X , Adulto Jovem
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