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1.
Actas Urol Esp ; 35(6): 325-30, 2011 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-21477886

RESUMO

INTRODUCTION: To evaluate the effects of percutaneous radiofrequency sacral rhizotomy in spinal cord injured (SCI) patients on urodynamic parameters (maximum cystometric capacity - MCC and detrusor pressure at maximum cystometric capacity - PdetMCC). MATERIAL AND METHODS: This prospective study assessed eight patients with SCI (four men and four women) with a mean age of 31.3years (22 to 41). Mean interval period between spinal cord lesion and rhizotomy was 53.5 months (20 to 96). All patients underwent an anesthetic block of the 3rd sacral root bilaterally using 0.5% bupivacaine under fluoroscopic control. Those who responded with an increase on bladder capacity were selected to undergo the percutaneous radiofrequency sacral rhizotomy. All patients underwent urodynamic evaluation at 6 and 12 months following the procedure. MCC and P(det)MCC were recorded. RESULTS: All patients presented a significant improvement on MCC after 12 months. The mean vesical volume increased from 100.2±57.1 to 282.9±133.4ml (p<0.05). The P(det)MCC reduced from 82.4±31.7 to 69.9±28.7cmH(2)O (p=0.2). Three patients with autonomic dysreflexia had complete relief of symptoms after the procedure. At 12 months, recurrence of detrusor hyperactivity was observed in all patients. One patient presented abolishment of reflex erections after the procedure. No major complications related to the rhizotomy were noted. CONCLUSIONS: Percutaneous radiofrequency sacral rhizotomy is a minimally invasive technique with low morbidity able to increase MCC. There is a trend towards the reduction of the P(det)MCC in SCI patients at 12 months, although statistical significance was not reached.


Assuntos
Ablação por Cateter/métodos , Rizotomia/métodos , Traumatismos da Medula Espinal/complicações , Bexiga Urinaria Neurogênica/cirurgia , Bexiga Urinária Hiperativa/cirurgia , Adulto , Feminino , Seguimentos , Humanos , Masculino , Bloqueio Nervoso , Tamanho do Órgão , Estudos Prospectivos , Resultado do Tratamento , Bexiga Urinária/patologia , Bexiga Urinaria Neurogênica/etiologia , Bexiga Urinaria Neurogênica/patologia , Bexiga Urinária Hiperativa/etiologia , Urodinâmica , Adulto Jovem
2.
Actas Urol Esp ; 32(7): 737-44, 2008.
Artigo em Espanhol | MEDLINE | ID: mdl-18788491

RESUMO

Reports on postoperative complications of anti-incontinence surgery followed the widespread use of synthetic slings. In this paper we describe the more frequent complications, such as obstruction, pelvic hematoma, bladder and urethral injuries, to facilitate the management of these complications.


Assuntos
Hematoma/etiologia , Hematoma/terapia , Slings Suburetrais/efeitos adversos , Obstrução do Colo da Bexiga Urinária/etiologia , Obstrução do Colo da Bexiga Urinária/terapia , Algoritmos , Feminino , Humanos , Obstrução do Colo da Bexiga Urinária/diagnóstico , Obstrução do Colo da Bexiga Urinária/fisiopatologia
3.
Int Urogynecol J Pelvic Floor Dysfunct ; 14(2): 108-12, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12851753

RESUMO

The authors quantified the collagen and elastic fibers in the bladder wall of ovariectomized rats with and without estradiol replacement. This study was conducted on 60 3-month-old Wistar rats. Group 1 remained intact; group 2 underwent bilateral ovariectomy and were sacrificed after 30 days; group 3 were sham operated and sacrificed after 30 days; group 4 had a bilateral ovariectomy and after 30 days were started on subcutaneous injections of 17beta-estradiol (10 microg/kg body weight) for 90 days; group 5 were sham operated and after 30 days were on started subcutaneous sesame oil replacement (0.2 ml/day) for 90 days; group 6 had a bilateral ovariectomy and after 30 days were started on subcutaneous sesame oil replacement (0.2 ml/day) for 90 days. Sirius red and Weigert's resorcin-fuchsin were used to stain collagen and elastic fibers on paraffin-embedded rat bladder sections. The M-42 grid system was used to quantitatively analyze the fibers. Ovariectomy had no effect on the volumetric density and absolute volume of the collagen and elastic fibers in the bladder wall of rats, or on the weight of the bladder. Estradiol replacement in castrated animals did not demonstrate any significant difference in the stereological parameters compared to the castrated group without hormonal replacement.


Assuntos
Colágeno/análise , Estradiol/farmacologia , Ovariectomia/veterinária , Bexiga Urinária/ultraestrutura , Animais , Tecido Elástico , Estradiol/administração & dosagem , Terapia de Reposição de Estrogênios , Feminino , Ratos , Ratos Wistar , Bexiga Urinária/química
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