RESUMO
INTRODUCTION: Non-volatile oleoresins from neotropical Burseraceae are traditionally used for craft, technological and medicinal purposes. The crude resin is usually sold in popular markets of the forest communities. Adding value to this rainforest raw material requires establishing its composition. OBJECTIVE: To analyse the resin composition from different Burseraceae species and establish a minimally reproducible profile by gas chromatography, in order to parameterise its quality control. METHODOLOGY: Crude oleoresin samples of 10 Protium and Trattinnickia species and a commercial blend were subjected to hydrodistillation to remove volatile compounds. The chloroform-soluble residues were methylated, analysed by GC-FID (flame ionisation detection), and individual components were identified by analysing their mass fragmentation pattern in GC-MS and comparison with data from the literature. The blend solubility was assayed in 30 non-chlorinated solvents at three different proportions. RESULTS: The resins consisted exclusively of triterpenes, showing a common predominance of four major compounds in all the samples, corresponding to α-amyrin, ß-amyrin, α-amyrenone and ß-amyrenone. This profile was complemented with minor amounts of the tetracyclic ß-elemolic and α-elemolic acids, maniladiol, brein and other oxidised trace compounds. The better solvents for the resin were those chemically bearing more than four carbon atoms, as n-butyl acetate, 2-ethoxyethanol and isopropanol. The crude resin blend sold contained around 10% of insoluble material that was constituted by up to 70% inorganic residues mixed with humic acid derivatives, as attested by ash analysis and IR spectroscopy, respectively. CONCLUSION: The experimental results, complemented by a general inspection of the literature, demonstrated a systematically reproducible triterpene profile in Protium and Trattinnickia species.
Assuntos
Burseraceae/química , Extratos Vegetais/química , Resinas Vegetais/química , Destilação/métodos , Cromatografia Gasosa-Espectrometria de Massas , Metilação , Estrutura Molecular , Peso Molecular , Ácido Oleanólico/análogos & derivados , Ácido Oleanólico/química , Ácido Oleanólico/isolamento & purificação , Extratos Vegetais/análise , Controle de Qualidade , Reprodutibilidade dos Testes , Resinas Vegetais/análise , Solubilidade , Solventes/química , América do Sul , Triterpenos/análise , Triterpenos/química , Compostos Orgânicos Voláteis/químicaRESUMO
In spite of the progress made in treating the different opportunistic illness in HIV syndrome, prevention remains the only real answer we have in stopping the spread of this disease. Programmes using new, innovative and interactive materials are necessary to reach a maximum number of people.
Assuntos
Síndrome da Imunodeficiência Adquirida/prevenção & controle , Educação em Saúde/métodos , Jogos e Brinquedos , Adolescente , Brasil , Criança , Feminino , Humanos , MasculinoRESUMO
The authors studied the viminol-p-hydroxybenzoate (RN: Dividol) through some psychopharmacological tests, making its comparison with neuroleptic and narcotic drugs, with the principal aim of determining if its analgesic action is correlated with a narcotic or psychotropic activity or both of them. The results are discussed.