Assuntos
Carcinoma Basocelular/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Nevo/diagnóstico , Neoplasias Cutâneas/diagnóstico , Adulto , Carcinoma Basocelular/patologia , Dermoscopia , Feminino , Humanos , Microscopia Confocal , Neoplasias Primárias Múltiplas/patologia , Nevo/patologia , Neoplasias Cutâneas/patologiaRESUMO
Superficial angiomyxomas (SA) of the skin are rare benign cutaneous tumors of soft tissue composed of prominent myxoid matrix and numerous blood vessels. SA are more common in males [1] and they are usually located on the trunk but can also appear on the lower limbs, head, neck and genitalia [2,3]. Treatment is surgical, the total excision is curative, but local recurrence is possible [4]. Herein we present a 72-year-old patient with a history of melanoma in situ, with a new lesion on the lower back.
Assuntos
Hipopigmentação/patologia , Nevo Pigmentado/patologia , Neoplasias Cutâneas/patologia , Adulto , Biópsia por Agulha , Dermoscopia/métodos , Diagnóstico Diferencial , Feminino , Humanos , Hipopigmentação/diagnóstico , Imuno-Histoquímica , Masculino , Microscopia Confocal/métodos , Pessoa de Meia-Idade , Nevo Pigmentado/diagnóstico , Estudos de Amostragem , Neoplasias Cutâneas/diagnósticoAssuntos
Carcinoma de Células Renais/secundário , Dermoscopia , Neoplasias Faciais/secundário , Neoplasias Renais/patologia , Neoplasias Cutâneas/secundário , Idoso , Carcinoma de Células Renais/patologia , Bochecha , Neoplasias Faciais/patologia , Humanos , Masculino , Neoplasias Cutâneas/patologiaRESUMO
Basal cell naevus syndrome is an inherited autosomal dominant genetic disorder characterised by multiple basal cell carcinomas (BCC), skeletal, neurological and opthalmological abnormalities. The treatment of choice of the often multiple and large BCC consists of a combined approach including surgery, liquid nitrogen and other topical treatment modalities. Imiquimod 5% cream is an immune-response-modifying drug with antiviral and anti-tumour activity. Recent reports have associated the immune-stimulant properties of imiquimod with the exacerbation of several autoimmune skin diseases, such as eczema, psoriasis, vitiligo and lichenoid dermatitis. Here we report a patient with basal cell naevus syndrome who developed a lichen planopilaris on the same site of the scalp, which had been previously treated with two cycles of imiquimod for multiple BCC.