RESUMO
The aim of this study is to evaluate the association between vitamin D status and glycemic profile in postmenopausal women with type 2 diabetes. A cross-sectional study was carried out with 70 (59.47⯱â¯6.47 years; 1.56⯱â¯0.05â¯m; 73.56⯱â¯13.01â¯kg; 30.30⯱â¯5.00 BMI kg/m2) postmenopausal women with type 2 diabetes (T2D). The blood samples were collected after fasting for 12â¯h and the main outcome parameters were serum follicle-stimulating hormone (FSH), estradiol; 25-OH vitamin D; insulin; C-Reactive Protein; cholesterol total (CT), triglycerides (TG), high density lipoprotein (HDL-cholesterol), glucose; calcium, HDL-cholesterol. The average serum 25(OH)D level in this study was 28.45⯱â¯8.26â¯ng/mL. The prevalence of hypovitaminosis D was 60%. Table 1 displays mean and standard deviation values for participants' characteristics. The postmenopause status of the women studied was confirmed by FSH and estradiol measurement. All the clinical and anthropometric characteristics did not show difference (pâ¯>â¯0.05) between the groups (Table 2). Triglycerides level was highest (pâ¯<â¯0.0391) in the hypovitaminosis D group. The other serum markers did not show statistical differences (pâ¯>â¯0.05) between the groups. In conclusion, our results suggest that only TG level shows a negative correlation with vitamin D status in postmenopausal women with type 2 diabetes.
Assuntos
Biomarcadores/sangue , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/epidemiologia , Índice Glicêmico , Pós-Menopausa/sangue , Deficiência de Vitamina D/epidemiologia , Vitamina D/sangue , Glicemia/análise , Estudos Transversais , Diabetes Mellitus Tipo 2/complicações , Feminino , Seguimentos , Hemoglobinas Glicadas/análise , Humanos , Incidência , Lipídeos/sangue , Pessoa de Meia-Idade , Prognóstico , Triglicerídeos/sangue , Deficiência de Vitamina D/complicações , Vitaminas/sangueRESUMO
AIMS: The aim of this study was to examine the association between muscle function, and body composition, vitamin D status, and blood glucose in post-menopausal women with type 2 diabetes (T2D). METHODS: Forty post-menopausal women (62.48±7.67years; 154.6±5.11cm; 73.93±15.43kg; 31.13±5.82 BMI kg/m2) with a diagnosis of T2D participated in this cross-sectional study. The patients performed fasting blood sample exams, anthropometrics assessments, body composition, and clinical exams. Subjects performed physical tests including handgrip, timed up and go, 30-s chair stand, arm curl, and sit-to-stand. The correlation between the parameters of physical tests, age, body composition, vitamin D, and blood glucose was assessed by Pearson correlation. RESULTS: The results showed there were significant correlations between blood glucose and relative strength (R=-0.398, p=0.011), arm curl test (R=-0.367 and p=0.020), and hip flexion (R=0.427, p=0.006). CONCLUSIONS: These findings are important because they highlight the importance of resistance training in individuals with T2D and the relationship with a fat increase during a dicrease process. Furthermore, the concentration of serum glucose might be associated with decreases in muscle strength and muscle function in older adults. Thus, T2D patients should be involved with strength training to improve the strength and the muscle hypertrophy.