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This study aimed to assess the combined effect of hypoxia and exposure to diesel on biochemical parameters of Perna perna mussels. Mussels previously kept for 48 h in clean seawater were submitted to hypoxia for 24 h followed by reoxygenation in clean seawater for 48 h. The same procedure was done but using seawater containing 0.01 mL/L of diesel, before and after hypoxia. Antioxidant enzymes as well as levels of glutathione and lipid peroxidation were measured in gills and digestive glands. The neutral red retention time assay was also evaluated in hemocytes. Results showed that cycles of air exposure and reoxygenation caused oxidative stress and antioxidant modulation in both the gills and digestive glands. The presence of diesel in water triggered additional modulation of antioxidants under hypoxia and reoxygenation stress, apparently enhancing the capacity of mussels to avoid lipid peroxidation.

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BACKGROUND: The arrival of COVID-19 in Brazil and the accelerated process of dissemination/contamination added to the evolution of the clinical picture of the disease, and the saturation of the capacity of health services, creating new challenges for researchers, governments, and professionals involved in the occupational health area. OBJECTIVE: This article aims to systematize and synthesize the proposals adopted by the legislation and by the Brazilian State, with a focus on worker protection and guaranteeing a safe work environment for the performance of their professional activities. METHODS: This is qualitative bibliographical research of the narrative literature review type, developed from October 2020 to June 2021 in legislation databases using the strategy: "COVID-19" AND "coronavirus/coronavirus" AND "worker health" on official Brazilian government websites. RESULTS: The lack of an emergency plan for efficient actions to respond to the epidemic caused and is still causing the daily deaths of workers. CONCLUSION: There is a need to guarantee the effectiveness of national and international policies and norms that have been neglected by the Brazilian government.

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Resumo Introdução A deficiência é uma construção social, e a integração no ensino superior é um direito dos estudantes com deficiência. Terapeutas ocupacionais atuam diretamente nesse contexto e podem apoiar participação social desses estudantes, assumindo o papel de gestão de programas na universidade. Objetivo Discutir ações realizadas por terapeutas ocupacionais gestoras de núcleos de inclusão em instituição de ensino superior. Método Estudo ancorado em abordagem qualitativa. Participaram cinco terapeutas ocupacionais, coordenadoras de programas de inclusão em diferentes regiões do Brasil e foram analisadas suas contribuições em relação às atividades realizadas no programa. Os dados foram coletados por meio de entrevistas semiestruturadas, sendo categorizados de acordo com seu conteúdo. Resultados A especificidade da intervenção no espaço educacional pressupõe equiparar ações em diferentes contextos do ambiente universitário. As ações de terapeutas ocupacionais gestoras perpassam intervenções focalizadas nas dimensões de apoio mais individual e intervenções mais coletivas, que interferem diretamente na mudança de cultura e acesso à universidade. Conclusão Destaca-se a habilidade de terapeutas ocupacionais como gestoras, num papel de mediadoras e atuantes na implementação de ações, de modo que parcerias institucionais produzam um diálogo entre necessidades e recursos, articulando demandas institucionais e a singularidade dos estudantes e dos processos educativos.

Abstract Introduction Disability is a social construction, and integration into higher education is a right of students with disabilities. Occupational therapists work directly in this context and can support the social participation of these students, assuming the role of program management at the university. Objective To discuss actions carried out by occupational therapists who manage inclusion centers in a higher education institution. Method Study anchored in a qualitative approach. Five occupational therapists, coordinators of inclusion programs in different regions of Brazil, participated and their contributions were analyzed in relation to the activities carried out in the program. Data were collected through semi-structured interviews, being categorized according to their content. Results The specificity of intervention in the educational space presupposes equating actions in different contexts of the university environment. The actions of managerial occupational therapists permeate interventions focused on the dimensions of more individual support and more collective interventions, which directly interfere in the change of culture and access to the university. Conclusion The ability of occupational therapists as managers is highlighted, in a role of mediators and actors in the implementation of actions, so that institutional partnerships produce a dialogue between needs and resources, articulating institutional demands and the uniqueness of students and educational processes.

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O Núcleo Poiesis -Laboratório Interinstitucional de Terapia Ocupacional e Trabalho, nasceu da vontade de estabelecer ações coletivas, parcerias interinstitucionais e experimentações acadêmicas entre docentes e terapeutas ocupacionais que estudam o trabalho. Esse relato de experiência descreve o processo deconstrução do Núcleo Poiesis, apresenta o perfil de suas pesquisadoras,suas produções e parcerias, seus projetos futuros e as contribuiçõesdesse grupo para os estudos e práticas sobre terapia ocupacionale trabalho. Enquanto coletivo, as produções somaram até então doisartigos, quatro capítulos de livros, além de parcerias interinstitucionaisem ensino, pesquisa e extensão, coordenação de debates sobreterapia ocupacional e trabalho nos principais congressos, eventose instituições representativas da profissão no país. Conclui-se quea experiência coletiva de pares promoveu uma interlocução entreas universidades espalhadas por todo território nacional, o que éindispensável para promover trocas de experiências, saberes e práticas no campo do trabalho e Terapia Ocupacional.

he Poiesis Nucleus - Interinstitutional Laboratory of Occupational Therapy and Work was born from the desire to set collective actions, inter-institutional partnerships, and academic dialogues between professors and occupational therapists that study work. This experience report describes the Nucleus building process. Also, it presents a profile of its researchers' members, productions, partnerships, future projects, and the contributions of this group to the studies and practices about occupational therapy and work. As a collective, the productions have summed up to two papers, four book chapters, inter-institutional partnerships in teaching, research, and extension activities, and debates about Occupational Therapy and work in academic events, with the leading professional's institutions in the country. It is concluded that the collective experience of peers promoted a dialogue between universities spread throughout the national territory, which is essential to promote exchanges of experiences, knowledge, and practices in the work field and Occupational Therapy

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Studies of forest species under different environmental conditions are essential for enhancing our understanding of plant-environment relationships. Different light conditions interfere with the production of seedlings within forests, and this interference can be verified by assessing leaf area. However, several species have leaf compound that often contain numerous leaflets, which makes the direct measurement of leaf area difficult. This leads researchers to question whether these types of leaves should be separated for analysis or measured whole. Thus, the aim of this study was to analyse specific leaf area in whole leaves and detached leaflets of six forest species subjected to different levels of shading. The forest species assessed all produced compound leaves and included Schinus terebinthifolius Raddi (aroeira), Schinopsis brasiliensis Engl. (braúna), Dalbergia nigra (Vell.) Fr. All. ex Benth. (jacaranda-da-bahia), Chorisia speciosa A. St.-Hil (paineira), Caesalpinia peltophoroides Benth (sibipiruna) and Plathymenia reticulata Benth (vinhático). Each species was subjected to six different degrees of shading: 0% (full sun); 20; 40; 60; 80 and 90%. Sombrite netting was used to shade plants. The analysis of the specific leaf area was performed using two different methods, which included the analysis of separate leaflets and whole leaves. To analyse leaflet area,50 leaflets per plant were assessed three times, and six plants per treatment were assessed. To assess whole leaves, data were obtained from the whole leaves of six plants per treatment. This process was repeated for all aforementioned species. Data obtained from both analysis methods indicated that all species assessed were similarly affected by shade, and leaf area varied according to the level of shading. This similarity of data demonstrates that, for these species, itis not necessary to use complex methods to obtain specific leaf area measurements. Thus, determining specific [...].

Estudos com espécies florestais, em diferentes condições ambientais são essenciais para o entendimento da relação planta-ambiente. Diferentes condições de luminosidade podem interferir na produção de mudas florestais e o reflexo dessa interferência pode ser verificado pela análise da área foliar. No entanto, muitas espécies apresentam folhas compostas, sendo muitas vezes com inúmeros folíolos, o que dificulta as análises com mensuração direta da área foliar, proporcionando dúvidas durante a análise, se devem ser separados para análise ou mensurados com a folha inteira. Assim, o objetivo desse estudo foi analisar a área foliar específica em folhas inteiras e folíolos destacados de folhas compostas de seis espécies florestais submetidas à diferentes níveis de sombreamento. As espécies florestais utilizadas foram Schinus terebinthifolius Raddi (aroeira), Schinopsis brasiliensis Engl. (braúna), Dalbergia nigra (Vell.) Fr. All. ex Benth. (jacarandá-da-bahia), Chorisia speciosa A.St.-Hil (paineira), Caesalpinia peltophoroides Benth (sibipiruna) e Plathymenia reticulata Benth (vinhático), todas com folhas compostas. Cada espécie foi submetida a seis tratamentos de sombreamento: 0% (pleno sol); 20;40; 60; 80 e 90%, com a utilização de "sombrites" para os tratamentos sombreados. A análise da área foliar específica foi realizada de duas maneiras: folíolos separados e folha inteira. Para a análise dos folíolos esses foram obtidos de três medidas (repetições) de 50 folíolos por planta, realizada em seis plantas por tratamento. Para a análise da folha inteira os dados foram obtidos de folhas inteiras de seis plantas por tratamento. Esse processo se repetiu em todas as espécies supramencionadas. Para todas as espécies, os dados indicaram um padrão de resposta semelhante em ambos os métodos de análise, [...].

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Studies of forest species under different environmental conditions are essential for enhancing our understanding of plant-environment relationships. Different light conditions interfere with the production of seedlings within forests, and this interference can be verified by assessing leaf area. However, several species have leaf compound that often contain numerous leaflets, which makes the direct measurement of leaf area difficult. This leads researchers to question whether these types of leaves should be separated for analysis or measured whole. Thus, the aim of this study was to analyse specific leaf area in whole leaves and detached leaflets of six forest species subjected to different levels of shading. The forest species assessed all produced compound leaves and included Schinus terebinthifolius Raddi (aroeira), Schinopsis brasiliensis Engl. (braúna), Dalbergia nigra (Vell.) Fr. All. ex Benth. (jacaranda-da-bahia), Chorisia speciosa A. St.-Hil (paineira), Caesalpinia peltophoroides Benth (sibipiruna) and Plathymenia reticulata Benth (vinhático). Each species was subjected to six different degrees of shading: 0% (full sun); 20; 40; 60; 80 and 90%. Sombrite netting was used to shade plants. The analysis of the specific leaf area was performed using two different methods, which included the analysis of separate leaflets and whole leaves. To analyse leaflet area,50 leaflets per plant were assessed three times, and six plants per treatment were assessed. To assess whole leaves, data were obtained from the whole leaves of six plants per treatment. This process was repeated for all aforementioned species. Data obtained from both analysis methods indicated that all species assessed were similarly affected by shade, and leaf area varied according to the level of shading. This similarity of data demonstrates that, for these species, itis not necessary to use complex methods to obtain specific leaf area measurements. Thus, determining specific [...].(AU)

Estudos com espécies florestais, em diferentes condições ambientais são essenciais para o entendimento da relação planta-ambiente. Diferentes condições de luminosidade podem interferir na produção de mudas florestais e o reflexo dessa interferência pode ser verificado pela análise da área foliar. No entanto, muitas espécies apresentam folhas compostas, sendo muitas vezes com inúmeros folíolos, o que dificulta as análises com mensuração direta da área foliar, proporcionando dúvidas durante a análise, se devem ser separados para análise ou mensurados com a folha inteira. Assim, o objetivo desse estudo foi analisar a área foliar específica em folhas inteiras e folíolos destacados de folhas compostas de seis espécies florestais submetidas à diferentes níveis de sombreamento. As espécies florestais utilizadas foram Schinus terebinthifolius Raddi (aroeira), Schinopsis brasiliensis Engl. (braúna), Dalbergia nigra (Vell.) Fr. All. ex Benth. (jacarandá-da-bahia), Chorisia speciosa A.St.-Hil (paineira), Caesalpinia peltophoroides Benth (sibipiruna) e Plathymenia reticulata Benth (vinhático), todas com folhas compostas. Cada espécie foi submetida a seis tratamentos de sombreamento: 0% (pleno sol); 20;40; 60; 80 e 90%, com a utilização de "sombrites" para os tratamentos sombreados. A análise da área foliar específica foi realizada de duas maneiras: folíolos separados e folha inteira. Para a análise dos folíolos esses foram obtidos de três medidas (repetições) de 50 folíolos por planta, realizada em seis plantas por tratamento. Para a análise da folha inteira os dados foram obtidos de folhas inteiras de seis plantas por tratamento. Esse processo se repetiu em todas as espécies supramencionadas. Para todas as espécies, os dados indicaram um padrão de resposta semelhante em ambos os métodos de análise, [...].(AU)

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OBJECTIVE: The study evaluated the longevity, effectiveness, safety, and impact on the oral health-related quality of life of in-office dental bleaching using low-concentration hydrogen peroxides. MATERIALS AND METHODS: Randomized, parallel, and double-blinded clinical trial was performed with 54 participants using 6% or 15% hydrogen peroxide (HP) in-office bleaching activated via hybrid LED/laser light. Tooth color was evaluated at baseline (T1), 1 week of bleaching (T2), 2 weeks of bleaching (T3) and 1 week (T4) and 6 months (T5) after finishing the bleaching using the Classical Vita™ scale and spectrophotometer. Tooth sensitivity and gingival irritation were measured with Visual Numeric Scale and Modified Gingival Index. The impact on quality of life was evaluated using the Oral Impact on Daily Performance. The data were analyzed using the Friedman, Mann-Whitney, and McNemar tests (p < 0.05). RESULTS: The group HP15% presented significant color change (ΔE) from T1 to T4 (p = 0.002) and T1 to T5 (p < 0.001). Parameters L, a*, and b* differed significantly at T3, T4, and T5 compared T1 for both groups. At 6-month follow-up, 57.1% of HP6 and 43.7% of HP15% participants migrated from B1 to a darker color. No significant differences were observed between the groups in tooth sensitivity, gingival irritation, or impact on quality of life. CONCLUSIONS: Both agents showed bleaching effectiveness, but HP15% presented greater color stability than HP6%, at 6-month follow-up. The agents showed low levels of tooth sensitivity, gingival irritation, and did not affect the oral health-related quality of life of the participants. CLINICAL RELEVANCE: Despite the greater presence of sensitivity during treatment compared with 6% hydrogen peroxide, 15% hydrogen peroxide demonstrated better bleaching effectiveness, and greater color stability at the end of bleaching and at 6-month follow-up. The use of 15% hydrogen peroxide presents more suitable results.

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Abstract Introduction: Inclusion programs for students with disabilities in Federal Institutions of Higher Education (IFES) seek to favor access and permanence based on respect for diversity in the university environment. The Occupational Therapy can help developing these programs. Objective: To analyze the access of the population with disabilities to higher education, considering the premises of the Inclusion Program INCLUIR of the Ministry of Education. Reflect on the contribution of occupational therapists in this program. Method: The descriptive-analytical research based on documentary analysis identified 55 Inclusion Program centers in the IFES, recognizing the developed actions. We studied the curriculum and research groups in the IFES with an occupational therapy course regarding this subject. We interviewed three occupational therapists that coordinated these programs. Results: We observed progress in the inclusion of people with disabilities in higher education, encouraged by government programs. The occupational therapy curriculum of the 14 IFES, as well as their research groups, do not indicate activities in the area of Education, which would make it difficult to practice professional technical actions in the area. Eight of the 55 nuclei have occupational therapists with a differential action of the professional capacity to perceive and favor the contact with the diversity of realities among students, which would potentialize equalization actions in the daily academic life, especially the permanence of people with deficiency. Conclusion: There is an urgent need to increase inclusion programs and the participation of occupational therapist, to increase the organization and management of actions for more dialogue between the IFES instances and to favor the entry and stay of students with disabilities.

Resumo Introdução: Programas de inclusão de estudantes com deficiência (EcD) em Instituições Federais de Ensino Superior (IFES) buscam favorecer acesso e permanência considerando-se o respeito à diversidade no ambiente universitário. A terapia ocupacional pode contribuir para desenvolver esses programas. Objetivo: Analisar o acesso da população com deficiência ao Ensino Superior, considerando as premissas do Programa INCLUIR do Ministério da Educação, além de refletir sobre a contribuição de terapeutas ocupacionais nesse programa. Método: Investigação descritiva-analítica baseada em análise documental identificou 55 núcleos do Programa INCLUIR em IFES, reconhecendo ações desenvolvidas. Nas IFES que ministravam graduação em terapia ocupacional, foram estudados os currículos e grupos de pesquisa relacionados ao tema. Foram entrevistadas três terapeutas ocupacionais coordenadoras desses programas. Resultados: Observou-se progresso na inclusão de pessoas com deficiência no ensino superior, incentivado pelos programas governamentais. Os currículos de terapia ocupacional das 14 IFES que oferecem graduação e seus grupos de pesquisa não indicam atividades na área da Educação, o que dificultaria o exercício de ações técnicas profissionais nesse campo. Oito dos 55 núcleos contam com terapeutas ocupacionais e neles há um diferencial da ação pela capacidade profissional de perceber e favorecer o contato com a diversidade de realidades entre estudantes, o que potencializaria as ações de equiparação no cotidiano acadêmico, favorecendo especialmente a permanência. Conclusão: Há necessidade de aumentar os programas de inclusão e a participação da terapia ocupacional, de forma a ampliar a organização e o gerenciamento de ações para maior diálogo entre as instâncias das IFES, e favorecer o ingresso e permanência de estudantes.

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Um dos maiores desafios atuais da ciência dos materiais dentários é a obtenção de união efetiva e durável às cerâmicas de alto conteúdo cristalino. O objetivo do presente estudo foi avaliar a resistência de união, energia de superfície e tipos de fratura de dois sistemas cerâmicos após diferentes formas de tratamento de superfície associada à aplicação do plasma em pressão atmosférica. Para o estudo foram obtidas quarenta placas de zircônia (12 mm x 5 mm x 1,5 mm) de dois tipos de cerâmicas zircônia (E.max ZirCad e Calypso), polidas e limpas por ultrassom durante 5 minutos. Divididas aleatoriamente em 2 grupos de acordo com o sistema cerâmico e 4 subgrupos (n=5) de acordo com o tratamento de superfície, (I) controle (primer), (II) jateamento com partículas micrométricas de alumina (Al2O3) + primer, (III) jateamento com partículas micrométricas de alumina (Al2O3) + plasma + primer, (IV) plasma + primer. Foram confeccionados cento e vinte cilindros de resina composta (Z100), utilizando matrizes cilíndricas (1,0 mm x 3,0 mm) cimentadas com cimento resinoso, Multilink N, sobre as placas de zircônia. Os espécimes foram armazenados em água destilada durante 24 horas a 37° C, depois testados para microcisalhamento em máquina de teste Shimadzu EZ a 1,0 mm/min. Os dados obtidos foram submetidos à análise estatística para comparação entre os grupos E.max e Calypso em relação à resistência à união (força/área ­ MPa), ângulo de contato e os tipos de fratura. Os dados foram analisados pelos testes ANOVA One-Way e Kruskal-Wallis para resistência de união (p=0,003) e (p=0,005) e ângulo de contato (p<0,001) e (p<0,001). Não houve diferença significativa para os dados de fratura (p=0,145), pelo teste quiquadrado, com predomínio de fraturas mistas. Os valores de resistência de união das cerâmicas Y-TZP apresentaram maiores valores quando o plasma foi associado ao jateamento com óxido de alumínio e/ou primer e a aplicação somente do plasma não superou os valores alcançados pelas outras formas de tratamento da superfície. Essa associação resultou em menores valores dos ângulos de contato. Houve maior frequência de fraturas mistas quando realizado somente o tratamento com óxido de alumínio e quando em associação com o plasma.(AU)

One of the major challenges today in the science of dental materials is the achievement of effective and durable bonding to ceramics with high crystalline content. The objective of the present study was to evaluate the efficacy of plasma at atmospheric pressure in the adhesion of ceramic zirconia through the bond strength, surface energy and type of fracture of two ceramic systems after different forms of surface treatment associated with the application of plasma at atmospheric pressure. For the study forty zirconia plates (12 mm x 5 mm x 1.5 mm) were obtained from two zirconia ceramics (E.max ZirCad and Calypso), polished and cleaned by ultrasound for 5 minutes. Randomly divided into 2 groups according to the ceramic system and 4 subgroups (n = 5) according to the surface treatment, control (primer), primer + blasting with micrometric alumina (Al2O3) particles, primer + blasting with micrometric particles of alumina (Al2O3) + plasma, primer + plasma. One hundred and twenty cylinders of composite resin (Z-100) were made using cylindrical matrices (1.0 mm x 3.0 mm) cemented on the zirconia plates. The specimens were stored in distilled water for 24 hours at 37°C, then tested for microshear on a Shimadzu EZ test machine at 0.5 mm / min. The obtained data were submitted to statistical analysis for comparison between the E.max and Calypso groups in relation to the bond strength (strength / area - Mpa), contact angle and fracture types. The data were analyzed by ANOVA One-Way and Kruskal-Wallis tests for bond strength (p=0.003) and (p=0.005) and contact angle (p<0.001) and (p<0.001). There was no significant difference for the fracture data (p = 0.145), by the chi-square test, with a predominance of mixed fractures. The bond strength values of the Y-TZP ceramics showed higher values when the plasma was associated with blasting with aluminum oxide and / or primer and the application of only the plasma did not exceed the values reached by the other forms of surface treatment. This association resulted in lower values of contact angles. It is a higher frequency of mixed fractures when only aluminum oxide treatment is performed and when it is associated with plasma.(AU)

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Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil and Mexico for ZIKV envelope domain III (ZEDIII) binding and neutralization. We find that serologic reactivity to dengue 1 virus (DENV1) EDIII before ZIKV exposure is associated with increased ZIKV neutralizing titers after exposure. Antibody cloning shows that donors with high ZIKV neutralizing antibody titers have expanded clones of memory B cells that express the same immunoglobulin VH3-23/VK1-5 genes. These recurring antibodies cross-react with DENV1, but not other flaviviruses, neutralize both DENV1 and ZIKV, and protect mice against ZIKV challenge. Structural analyses reveal the mechanism of recognition of the ZEDIII lateral ridge by VH3-23/VK1-5 antibodies. Serologic testing shows that antibodies to this region correlate with serum neutralizing activity to ZIKV. Thus, high neutralizing responses to ZIKV are associated with pre-existing reactivity to DENV1 in humans.

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