RESUMO
El cabello y especialmente el localizado en la cabeza provee importante información sobre posibles exposiciones ambientales y/o laborales a diferentes elementos. El pelo puede ser considerado como un producto excretor, y su estudio reflejaría el metabolismo de minerales en el cuerpo. Nuestro propósito en el presente estudio es conocer si datos existentes dan información poblacional sobre la presencia de elementos tóxicos o no a través del análisis del cabello humano. RESULTADOS: Fue analizada la información proveniente de 241 muestras de cabello, de los cuales 163 (67,6%) corresponden al sexo femenino y 78 (32,4%) al masculino. Fueron analizados 22 elementos esenciales y 17 elementos de tóxicos. Entre los elementos esenciales presentaron resultados elevados Calcio (Ca), Magnesio (Mg), Manganeso (Mn), Molibdeno (Mo), Vanadio (V), Estroncio (Sr) y Circonio (Zr); entre los elementos tóxicos tuvieron valores elevados Aluminio (Al), Arsénico (As), Bario (Ba), Bismuto (Bi), Cadmio (Cd), Níquel (Ni), Plomo (Pb), Mercurio (Mg), Plata (Ag), Estaño (Sn). CONCLUSIÓN. Nuestro estudio muestra a nivel poblacional, no individual, puntos de alerta por la carencia o exceso de algunos elementos analizados debiéndose continuar con estudios locales interdisciplinarios en los cuales exista información sobre enfermedades, hábitos alimentarios, hábitos tóxicos, actividad laboral y exposición ambiental a los diferentes elementos. (AU)
Hair, especially localized in the head, provides important information on possible environmental and/or labor exposures to different elements. Hair can be considered as an excretory product, and its study would reflect the metabolism of minerals in the body. Our purpose in this study was to determine whether existing population data provide information on the presence of toxic and non-toxic elements by analizing human hair. RESULTS: We analyzed information from 241 hair samples, of which 163 (67.6%) are from females and 78 (32.4%) are from males. There were analyzed 22 essential elements and 17 toxic elements. Among the essential elements that had elevated results there were: Calcium (CA), magnesium (Mg), manganese (Mn), molybdenum (Mo), vanadium (V), strontium (Sr) and zirconium (Zr); among the toxic elements, those with higher values were: Aluminum (Al), arsenic (As), barium (BA), bismuth (Bi), Cadmium (Cd), Nickel (Ni), lead (Pb), Mercury (Mg), silver (Ag), tin (Sn). CONCLUSION. Our study shows at population level, not individual, warning points due to the lack or excess of some elements analyzed. It is reccommended to continue the research with local interdisciplinary studies which include information on diseases, eating habits, toxic habits, work activity and environmental exposure to different elements. (AU)
Assuntos
Humanos , Masculino , Feminino , Metais Pesados/análise , Metais Pesados/química , Cabelo/química , Minerais/análise , Minerais/química , Epidemiologia Descritiva , Estudos Retrospectivos , Estudo ObservacionalRESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8% of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
Assuntos
Acloridria/fisiopatologia , Esvaziamento Gástrico , Gastrinas/sangue , Gastrite/fisiopatologia , Adulto , Idoso , Doença Crônica , Feminino , Suco Gástrico/metabolismo , Humanos , Índio , Masculino , Pessoa de Meia-Idade , Antro Pilórico/patologia , Antro Pilórico/fisiopatologia , RadioisótoposRESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8
of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
RESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8
of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
RESUMO
A group of 43 subjects was studied: 22 normal, 6 with gastric ulcers, and 15 with duodenal ulcers. A correlation was made between gastrinemia and basal gastric acid secretion. The findings suggest that the basal gastric secretion does not play an important role in either the basal gastrinemia in normal subjects or in those with gastric ulcers. The correlation was significant and negative between basal gastric secretion and basal gastrinemia in those with duodenal ulcers, which might express differences in the self-regulation of gastrinemia related to antral pH.