RESUMO
Despite widespread heparin use in clinical practice, the associated development of thrombocitopenia is an underrecognized and undertreaded complication. Methods:We analized data from consective hospitalized patients treated with heparin (unfractionated or low molecular weight) for four days or longer to determine the incidence, predictors, prognostic significance, and management of thrombocitopenia, defined as a platelet count less than 150x10/L, reduction in platelet count of 50% or more from teh admission level, or both...
Assuntos
Heparina , TrombocitopeniaRESUMO
Background Current guidelines advise the use of risk stratification to determine wich patients should receive more aggressive antithrombotic and invasive therapies. Our objective was to evaluatethe relationship between risk stratification and therapeutic decision makeing in patients with non-ST-segment elevation the relationship between risk stratification and therapeutic decision making patients with no-ST-segment elevation acute coronaru syndromes. Methods We analizes data from 15026 patients with acute coronary syndrome who were enrolled into the GRACE registry between 1999 and 2003. We assessed the evidence-based use od antithrombotic therapy and early invasive strategy according to risk profile defined by baseline troponin elevation, presenting ST-segment depression...