RESUMO
OBJECTIVE: To assess the prognostic value of mortality of a new system for quantifying the lesion length circumscribed to the genitals and adjacent anatomical areas in patients with Fournier's gangrene. METHODS: An observational, analytical and prospective study in the Urology service of the Arnaldo Milián Castro University Hospital, between January 2007 and December 2019. The sample consisted of 60 patients diagnosed with Fournier's gangrene. To determine the lesion length, a new quantification system was designed by the authors. Its predictive capacity was determined by binary logistic regression analysis and its discriminatory capacity by the area under the ROC curve. RESULTS: In the studied sample, Fournier's gangrene mortality was 26.7%. The logistic regression analysis demonstrated the prognostic value of mortality of the quantification system evaluated, for each point that the extension of the lesion increased, the risk of death increased by approximately five times, thus being superior to the methods previously used to quantify the injury. Results of the calibration of the quantification system by the Hosmer-Lemeshhow test showed that the data were adjusted to the regression equation (p = 0.278). An area under the curve of 0.957 was observed, which reflects a good discriminatory capacity, showing a sensitivity of 93.75% and a specificity of 93.18%. CONCLUSIONS: The system for quantifying the lesion length in patients with Fournier's gangrene proposed in the present study showed an excellent prognostic value for mortality. The integration of this new method into others prognostic scores could substantially increase sensibility and specificity on diagnostic, by means of offering a more precise approach of the lesion dimensions.
Assuntos
Gangrena de Fournier , Gangrena de Fournier/diagnóstico , Humanos , Masculino , Prognóstico , Estudos Prospectivos , Estudos Retrospectivos , Índice de Gravidade de DoençaRESUMO
Se presenta un caso de tuberculosis del área de salud del Policlínico Universitario "Raúl Sánchez". Se trata de una gestante de 19 años de edad, de color de la piel negra, adolescente, fumadora y con antecedentes de salud; transcurre además con un embarazo con sintomatología respiratoria. En el proceso de atención sus síntomas se interpretan como proceso bronco neumónico, un cuadro que empeora a los 20 días de parida y es ingresada en cuidados intensivos. Se le realiza la radiografía de tórax. La imagen realizada resulta sugestiva de una neumonía y se le indica tratamiento con antibióticos. Al no mejorar el cuadro respiratorio se interconsulta con neumología y se le diagnóstica tuberculosis pulmonar, se inicia tratamiento con la consiguiente mejoría de la paciente hasta su alta.
A 19-year old, black, pregnant, smoker adolescent suffering from tuberculosis and having health history of respiratory symptoms was attended at "Raul Sanchez" University Outpatient Clinic. During health assistance the symptoms were interpreted as a bronchopneumonia process, clinical manifestations worsened 20 days after the delivery and she was admitted in Intensive Care Unit. Thoracic images suggested a pneumonia and antibiotic therapy was indicated. As the patient did not show respiratory improvements she was referred to the pulmonologist where pulmonary tuberculosis was diagnosed. The patient started the treatment observing a subsequent good progress up to the hospital discharge.