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1.
Int J Tuberc Lung Dis ; 1(6): 536-41, 1997 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9487452

RESUMO

SETTING: San Francisco, California. OBJECTIVE: To determine the relative contributions of infection acquired in San Francisco and reactivation of tuberculous infection acquired elsewhere in Mexican-born persons who developed tuberculosis in San Francisco, and to determine the frequency of transmission leading to secondary cases of tuberculosis in other persons. DESIGN: The study population consisted of all Mexican-born tuberculosis patients reported in San Francisco from 1991 through June 1995. All patients had positive cultures for Mycobacterium tuberculosis and DNA fingerprinting of isolates using IS6110 with more than two bands. Patients were classified as infected in San Francisco or infected elsewhere based on pre-defined criteria that included a second DNA fingerprinting technique (polymorphic guanine-cytosine-rich sequence), chart reviews, and selected patient interviews. RESULTS: Of the 43 Mexican-born patients studied, nine (21%) met the definition of infection acquired in San Francisco and 34 (79%) met the definition of reactivation of infection acquired elsewhere. Only one of the 43 cases resulted in two secondary cases in US-born persons. CONCLUSION: One-fifth of the Mexican-born patients who developed tuberculosis in San Francisco acquired their tuberculous infection in San Francisco; transmission from Mexican-born persons leading to tuberculosis in other persons is uncommon.


Assuntos
Emigração e Imigração/estatística & dados numéricos , Tuberculose Pulmonar/etnologia , Análise por Conglomerados , Impressões Digitais de DNA , Humanos , México/etnologia , Mycobacterium tuberculosis/genética , São Francisco/epidemiologia , Tuberculose Pulmonar/microbiologia , Tuberculose Pulmonar/transmissão
4.
Am J Public Health ; 76(6): 643-6, 1986 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-3706591

RESUMO

Because of the concern that we were underestimating the prevalence of tuberculosis within the Latino community in San Francisco, we undertook a community-based screening program directed largely towards recent immigrants. Of 1,871 intermediate-strength (5 TU) tuberculin tests applied and read, 37 per cent of the reactions were greater than or equal to 10 mm. Significant reactions were found in 53 per cent of foreign-born persons compared to 7 per cent of those born in the United States. Persons older than 20 years of age were more likely to have significant reactions compared to younger Latinos. Among the foreign-born, the frequency of significant reactions was not influenced by the length of stay in the US or a history of BCG (bacille Calmette-Guérain) vaccination. Two foreign-born children were found to have current tuberculosis. The prevalence of tuberculin reactors among US-born Latino children was 3 per cent, which suggests that undetected transmission of tuberculosis may be occurring. We conclude that Latino immigrants should be systematically screened for tuberculosis.


Assuntos
Hispânico ou Latino , Tuberculose/epidemiologia , Adolescente , Adulto , Fatores Etários , Idoso , Vacina BCG , California , América Central/etnologia , Criança , Pré-Escolar , Emigração e Imigração , Métodos Epidemiológicos , Feminino , Humanos , Lactente , Masculino , México/etnologia , Pessoa de Meia-Idade , Teste Tuberculínico , Tuberculose/diagnóstico , Tuberculose/imunologia , Estados Unidos
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