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INTRODUCTION: Neurocysticercosis (NCC), a possible cause of epilepsy with limited epidemiological data in the Dominican Republic, is endemic in four provinces in the country's south-western region. This study aimed to determine the association between NCC and epilepsy among people living in these endemic regions, and to obtain preliminary data on the prevalence of NCC in these provinces. PATIENTS AND METHODS: A case-control design was used, consisting of 111 patients with epilepsy with unknown causes, and 60 controls without epilepsy or NCC. The diagnosis of NCC was based on computed tomography and magnetic resonance imaging of the skull, as well as Western immunoblotting for serum antibodies using Taenia solium, following the criteria of Del Brutto et al. RESULTS. NCC was found in 27% of the epileptic patients (n = 30/111) and in 5% of the controls (n = 3/60); the probability of the epileptic patients having NCC was seven times higher than the controls (odds ratio = 7.04, 95% confidence interval: 2.04-24.18; p < 0.001). The participants' sociodemographic characteristics, including their age, sex, level of education, occupation, and province of residence presented no statistical significance in terms of their association with NCC. CONCLUSIONS: This study suggests that NCC is strongly associated with epilepsy in the south-western region of the Dominican Republic, and highlights the need for public health measures to improve the prevention, diagnosis and treatment of both diseases.

TITLE: Diagnóstico de neurocisticercosis en pacientes con epilepsia residentes en el suroeste de la República Dominicana.Introducción. La neurocisticercosis (NCC), una posible causa de epilepsia con datos epidemiológicos limitados en la República Dominicana, es endémica en cuatro provincias de la región suroeste. El objetivo de este estudio fue determinar la asociación entre la NCC y la epilepsia en personas que viven en estas regiones endémicas, así como obtener datos preliminares sobre la prevalencia de NCC en estas provincias. Sujetos y métodos. Se utilizó un diseño de casos y controles compuesto por 111 pacientes con epilepsia de causa desconocida y 60 controles sin epilepsia ni NCC. El diagnóstico de NCC se basó en la tomografía computarizada y la resonancia magnética del cráneo, así como en el inmunotransferencia de Western para anticuerpos séricos contra Taenia solium, siguiendo los criterios de Del Brutto et al. Resultados. Se encontró NCC en el 27% de los pacientes con epilepsia (n = 30/111) y en el 5% de los controles (n = 3/60); los casos de epilepsia tenían siete veces más probabilidades de tener NCC que los controles (odds ratio = 7,04, intervalo de confianza al 95%: 2,04-24,18; p < 0,001). Las características sociodemográficas de los participantes, como la edad, el sexo, el nivel de escolaridad, la ocupación y la provincia de residencia no mostraron significación estadística en cuanto a la asociación con NCC. Conclusiones. Este estudio sugiere que la NCC está fuertemente asociada con la epilepsia en la región suroeste de la República Dominicana, y destaca la necesidad de medidas de salud pública para mejorar la prevención, el diagnóstico y el tratamiento de ambas enfermedades.

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The effect of four nitrogen levels (0, 40, 80 and 120kg N ha-1), applied before deferment on the beef cattle production and structural variables on Urochloa decumbens (signal grass) were assessed from January to October 2012 and from January to September 2013. A randomized block design with three replicates was adopted, in an arrangement of repeated measures in time (grazing period). An interaction effect between nitrogen level and grazing period was observed on extended-plant height and herbage mass. As the nitrogen levels were increased, extended-plant height, herbage mass, total herbage allowance, and efficiency of conversion of fertilizer into herbage were increased. Throughout the grazing period, pasture height, extended-plant height, percentage of leaves, herbage and morphological components allowance, and percentages of leaves and stems in the herbage apparently selected by the animal decreased. Nitrogen levels had no effect on average daily gain or gain per area in the first year. A fixed deferment period with increasing levels of nitrogen fertilization on signal grass pastures does not influence the average daily gain per animal, reduces the efficiency of the nitrogen fertilizer and negatively changes the structural characteristics of the pasture.(AU)

Foi avaliado o efeito de quatro doses de nitrogênio (0, 40, 80 e 120kg N ha -1 ), aplicadas antes do diferimento, sobre o desempenho de bovinos e as características estruturais de Urochloa decumbens (capim-braquiária), de janeiro a outubro de 2012 e de janeiro a setembro de 2013. Um delineamento de blocos ao acaso foi utilizado em arranjo de medidas repetidas no tempo (período de pastejo). Foi observada interação entre doses de nitrogênio e período de pastejo na altura da planta estendida e na massa de forragem. As doses de nitrogênio incrementaram a altura da planta estendida, a massa de forragem, a oferta de forragem e a eficiência de conversão do nitrogênio em forragem. No decorrer do período de pastejo, a altura do pasto, a altura da planta estendida, a porcentagem de lâminas foliares, a oferta de forragem e dos seus componentes morfológicos e a porcentagem de lâminas e colmos da forragem aparentemente selecionada pelos animais diminuíram. As doses de nitrogênio não exerceram efeito sobre o ganho diário e o ganho diário por área no primeiro ano. O período de diferimento fixo com aumento das doses de nitrogênio em pastos de capim-braquiária não influencia o ganho diário por animal, reduz a eficiência da adubação nitrogenada e afeta negativamente a estrutura do pasto.(AU)

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The effect of four nitrogen levels (0, 40, 80 and 120kg N ha-1), applied before deferment on the beef cattle production and structural variables on Urochloa decumbens (signal grass) were assessed from January to October 2012 and from January to September 2013. A randomized block design with three replicates was adopted, in an arrangement of repeated measures in time (grazing period). An interaction effect between nitrogen level and grazing period was observed on extended-plant height and herbage mass. As the nitrogen levels were increased, extended-plant height, herbage mass, total herbage allowance, and efficiency of conversion of fertilizer into herbage were increased. Throughout the grazing period, pasture height, extended-plant height, percentage of leaves, herbage and morphological components allowance, and percentages of leaves and stems in the herbage apparently selected by the animal decreased. Nitrogen levels had no effect on average daily gain or gain per area in the first year. A fixed deferment period with increasing levels of nitrogen fertilization on signal grass pastures does not influence the average daily gain per animal, reduces the efficiency of the nitrogen fertilizer and negatively changes the structural characteristics of the pasture.(AU)

Foi avaliado o efeito de quatro doses de nitrogênio (0, 40, 80 e 120kg N ha -1 ), aplicadas antes do diferimento, sobre o desempenho de bovinos e as características estruturais de Urochloa decumbens (capim-braquiária), de janeiro a outubro de 2012 e de janeiro a setembro de 2013. Um delineamento de blocos ao acaso foi utilizado em arranjo de medidas repetidas no tempo (período de pastejo). Foi observada interação entre doses de nitrogênio e período de pastejo na altura da planta estendida e na massa de forragem. As doses de nitrogênio incrementaram a altura da planta estendida, a massa de forragem, a oferta de forragem e a eficiência de conversão do nitrogênio em forragem. No decorrer do período de pastejo, a altura do pasto, a altura da planta estendida, a porcentagem de lâminas foliares, a oferta de forragem e dos seus componentes morfológicos e a porcentagem de lâminas e colmos da forragem aparentemente selecionada pelos animais diminuíram. As doses de nitrogênio não exerceram efeito sobre o ganho diário e o ganho diário por área no primeiro ano. O período de diferimento fixo com aumento das doses de nitrogênio em pastos de capim-braquiária não influencia o ganho diário por animal, reduz a eficiência da adubação nitrogenada e afeta negativamente a estrutura do pasto.(AU)

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BACKGROUND: The increase in the waiting list for a liver and the high mortality rate of patients with terminal liver disease represent serious public health problems in Brazil. OBJECTIVE: To analyze donations and liver transplants in the State of Paraná, Brazil. METHOD: A cross-sectional study was carried out with data from 3931 reports of deaths due to brain death and 8146 solid organ transplants made available by the State Transplant System of Paraná between 2011 and 2016. The data related to donation and liver transplantation were analyzed using descriptive statistics and inference. RESULTS: A total of 751 (28.9%) liver donations were carried out. Of these, the greatest chance of effectiveness occurred in patients younger than 50 years OR: 1.94 (CI: 1.60-2.34; P < .01) and male OR: 1.27 (CI: 1.06-1.52; P < .01). A total of 720 (8.8%) liver transplants were performed, most of which were funded by the Unified Health System. There was a significant increase in donations and liver transplants over the years. CONCLUSION: Donor numbers and liver transplants increased in the State but did not meet the need for the waiting list within the analyzed period.

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The characteristics of petal epidermal conical cells affect the quality of the signals perceived by various pollinators. This study aimed to identify variations in micromorphological characteristics of flower petals and their relationship to melittophily, ornithophily and chiropterophily pollination systems. The petals of 11 species were analysed using scanning electron microscopy and optical microscopy and the micromorphological traits were described, measured and compared using Tukey's test, PCA and cluster analysis. Unlike chiropterophily, all melittophilous and some ornithophilous species possessed adaxial epidermal conical cells. Cluster grouping separated chiropterophilous flowers from melittophilous and ornithophilous. PCA analysis showed that the two morphometric profile of conical cells was the attribute that most strongly influenced the grouping of species. When considering the data set of the three pollination systems, melittophilous and ornithophilous plants were more similar to each other than they were to chriopterophilous species. The distance between conical cell apices is an important parameter in interactions with pollinators. This study facilitated recognition of smoothing pollinator resource access through petal micromorphological characteristics. Further research regarding the biometry of micromorphological traits related to pollination is required.

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Objetivou-se avaliar os efeitos da planta daninha Solanum sisymbrifolium (joá-bravo) sobre o número e as características de perfilhos de Urochroa decumbens cv. Basilisk em pasto sob lotação contínua com bovinos. Foram avaliados dois locais do mesmo pasto, sendo um próximo, localizado a 0,5 m do caule principal da planta daninha, e outro distante, onde não havia ocorrência desta planta em 2,0 m de raio, por meio da quantificação do número, peso e morfologia dos perfilhos. O delineamento foi inteiramente ao acaso com três repetições. No local distante da planta daninha houve maior densidade populacional de perfilhos com desfolhação e sem o meristema apical. Os números de perfilhos basais e aéreos foram menores próximo da planta daninha. Este local também apresentou menores números de perfilhos vegetativos, reprodutivos, vivos, mortos e totais, quando comparado ao local distante da planta daninha. Os pesos de perfilhos vegetativos e reprodutivos foram maiores no local próximo do que no distante da planta daninha. Os perfilhos próximos da planta daninha apresentaram maiores comprimento do pseudocolmo e de lâmina foliar, superior número de folha viva e inferior número de folha pastejada em relação aos distantes. A ocorrência da planta S. sisymbrifolium ocasiona variabilidade espacial da vegetação no pasto de U. decumbens cv. Basilisk...

The objective of this study was to evaluate the effects of the weed Solanum sisymbriifolium (sticky nightshade) on the number and characteristics of Urochloa decumbens cv. Basilisk tillers in pasture continuously stocked by cattle. Two sites of the same pasture were evaluated, one site located close (0.5 m) to the main stalk of the weed and the other located at a distance where no weed was growing within a radius of 2.0 m. The number, weight and morphology of the tillers were evaluated in a completely randomized design with three repetitions. At the site distant from the weed, a higher population density of defoliated tillers without apical meristem was observed. The number of basal and aerial tillers was smaller close to the weed plant. This site was also characterized by smaller numbers of vegetative, reproductive, live, dead and total tillers when compared to the site distant from the weed plant. The weight of vegetative and reproductive tillers was higher at the site close to the weed plant. Tillers close to the weed plant exhibited a greater length of the pseudostem and leaf blade, a larger number of live leaves, and fewer grazed leaves compared to distant tillers. The occurrence of S. sisymbriifolium results in spatial variability of vegetation in U. decumbens cv. Basilisk pasture...

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Objetivou-se avaliar os efeitos da planta daninha Solanum sisymbrifolium (joá-bravo) sobre o número e as características de perfilhos de Urochroa decumbens cv. Basilisk em pasto sob lotação contínua com bovinos. Foram avaliados dois locais do mesmo pasto, sendo um próximo, localizado a 0,5 m do caule principal da planta daninha, e outro distante, onde não havia ocorrência desta planta em 2,0 m de raio, por meio da quantificação do número, peso e morfologia dos perfilhos. O delineamento foi inteiramente ao acaso com três repetições. No local distante da planta daninha houve maior densidade populacional de perfilhos com desfolhação e sem o meristema apical. Os números de perfilhos basais e aéreos foram menores próximo da planta daninha. Este local também apresentou menores números de perfilhos vegetativos, reprodutivos, vivos, mortos e totais, quando comparado ao local distante da planta daninha. Os pesos de perfilhos vegetativos e reprodutivos foram maiores no local próximo do que no distante da planta daninha. Os perfilhos próximos da planta daninha apresentaram maiores comprimento do pseudocolmo e de lâmina foliar, superior número de folha viva e inferior número de folha pastejada em relação aos distantes. A ocorrência da planta S. sisymbrifolium ocasiona variabilidade espacial da vegetação no pasto de U. decumbens cv. Basilisk...(AU)

The objective of this study was to evaluate the effects of the weed Solanum sisymbriifolium (sticky nightshade) on the number and characteristics of Urochloa decumbens cv. Basilisk tillers in pasture continuously stocked by cattle. Two sites of the same pasture were evaluated, one site located close (0.5 m) to the main stalk of the weed and the other located at a distance where no weed was growing within a radius of 2.0 m. The number, weight and morphology of the tillers were evaluated in a completely randomized design with three repetitions. At the site distant from the weed, a higher population density of defoliated tillers without apical meristem was observed. The number of basal and aerial tillers was smaller close to the weed plant. This site was also characterized by smaller numbers of vegetative, reproductive, live, dead and total tillers when compared to the site distant from the weed plant. The weight of vegetative and reproductive tillers was higher at the site close to the weed plant. Tillers close to the weed plant exhibited a greater length of the pseudostem and leaf blade, a larger number of live leaves, and fewer grazed leaves compared to distant tillers. The occurrence of S. sisymbriifolium results in spatial variability of vegetation in U. decumbens cv. Basilisk pasture...(AU)

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Schwannomas reach 8 to 10% of all intracranial tumors. Most originate at the vestibular root of VIII cranial nerve, but trigeminal tumors are infrequent. We present the case of a patient admitted at the National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez" (Mexico City) with a mass occupying the infratemporal fossa with involvement of nearby structures. Schwannomas with extension to the infratemporal fossa are rare. We review the anatomy of this region, the surgical approaches, which have been used and propose a different approach.

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On 3 September 2002, the Spanish national centre of epidemiology (Centro Nacional de Epidemiologia--CNE) was alerted to a high number of gastroenteritis cases in Spanish tourists who had travelled to a hotel in Punta Cana on different days during august 2002. Entamoeba hystolitica cysts have been visualised by microscopy in the stools of several patients that sought medical attention in the Dominican Republic. The CNE informed the health authorities in the Dominican Republic and conducted in conjunction an epidemiological investigation. A descriptive study of the 76 initial cases estimated a mean illness duration of 5.1+2.9 days and a exposure period of 3.6+2.2 days. Following a retrospective cohort study, the attack rate was found to be 32.4%. Consequently, 216 (95% CI=114.75-317.25) spanish tourists had probably developed the illness. Stool samples were collected in Spain from untreated patients who still felt unwell. None of the samples were positive for E.hystolitica. On 10 September, a hygiene inspection was undertaken at the hotel. Samples of the ice and meals served at the buffet that day, yielded coliform bacteria. Consumption of water from the resort water system was the only risk factor associated with the symptoms (RR= 3.55; 95% CI =1.13-10.99). To avoid similar outbreaks occurring again at the hotel, it is essential to regularly monitor the water quality and to improve food handling hygiene standards. Basic food hygiene training for food handlers should be mandatory. An international guideline for the management foodborne and waterborne outbreaks among tourists in holiday resorts should be drawn up, involving all competent authorities of both destination and tourist origin countries.

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Ultrathin sections of microfilaria of W. bancrofti embedded in the hydrophilic resin L.R. White were incubated with sera from patients with a typical picture of filarial tropical pulmonary eosinophilia (TPE) and sera from patients of a non-endemic region for filariasis regarding intestinal helminths. Both groups had a similar pattern of labelling, except that the labelling intensity was higher with the sera of patients with filarial TPE. The present study indicates relevant epitopes recognised by sera from TPE-patients and also individuals with intestinal helminths in all tissues of microfilaria of W. bancrofti, instead of being localised in a specific nematode region. These findings suggest that sera from people from an area not endemic for filaria, harbouring intestinal helminths, also share antifilarial antibodies that recognise antigens of microfilaria of W. bancrofti.

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