RESUMO
Social isolation (SI) is related to adverse neurobehavioral effects and neurochemical changes when it occurs early in development. On the other hand, environmental enrichment (EE) is associated with a reduction in anxiety-like and depression-like behavior, as well as an increase in serotonin (5-HT) levels in the prefrontal cortex and hippocampus in rodents. This study systematically reviewed the effects of SI and EE on emotional behavior and serotonergic system components in rats after weaning. Primary experimental studies that used subgroups of rats subjected to SI, EE, and normal social conditions after weaning were considered eligible. Studies that used transgenic rodents, ex vivo studies, in vitro studies, human research, or in silico studies were ineligible. Two authors completed searches in Medline/PubMed, LILACS, Scopus, Web of Science, EMBASE, and Open Gray. The Kappa index was calculated to assess agreement between reviewers and assess study quality. The results showed that the animals exposed to EE showed better adaptation to a new environment. Furthermore, EE increased 5-HT levels in the hippocampus and prefrontal cortex of rodents. Thus, it appears that an EE during the critical period of development may reduce anxiety/depression-like behaviors, as well as increase long-term neurotransmitter response.
Assuntos
Emoções , Meio Ambiente , Serotonina , Isolamento Social , Animais , Ratos , Ansiedade , Comportamento Animal/fisiologia , Emoções/fisiologia , Hipocampo/metabolismo , Córtex Pré-Frontal/metabolismo , Serotonina/metabolismo , Isolamento Social/psicologia , DesmameRESUMO
A infância é o período crucial para o desenvolvimento humano, onde as brincadeiras vivenciadas por crianças nos espaços públicos de lazer contribuem para o seu desenvolvimento físico, cognitivo e social. Mas, a problemática da pandemia da COVID-19 acarretou o distanciamento da população a esses espaços, resultando em uma nova configuração de vivenciar o brincar. O estudo tem como objetivo, registrar as características e singularidades da vivência cotidiana de jogos e brincadeiras por crianças em praças e parques públicos da cidade de Vitória de Santo Antão durante a flexibilização das medidas de restrições impostas pela pandemia da COVID-19. Através de um estudo exploratório descritivo, analítico. Foi possível observar que o comportamento do brincar estava atrelado à utilização dos equipamentos de lazer infantil presentes nas praças, e a pandemia da COVID-19, não atrapalhou de forma significativa esta ação.
Childhood is the crucial period for human development, where the games experienced by children in public leisure spaces contribute to their physical, cognitive, and social development. But, the problem of the COVID-19 pandemic led to the distancing of the population from these spaces, resulting in a new configuration of experiencing play. The study aims to record the characteristics and singularities of the daily experience of games and games by children in squares and public parks in the city of Vitória de Santo Antão during the easing of the restriction measures imposed by the COVID-19 pandemic. Through an exploratory descriptive, analytical study. It was possible to observe that the behavior of playing was linked to the use of children's leisure equipment present in the squares, and the COVID-19 pandemic did not significantly interfere with this action.
Assuntos
Área UrbanaRESUMO
Abstract Objective: The objective of this study was to analyze masticatory characteristics in children from 7 to 10 years, and to compare these characteristics among normal weight, overweight and obese children. Methods: This is a cross-sectional study, conducted in northeast Brazil, with a sample of 160 children, aged 7 to 10 years. The authors evaluated: nutritional and dental status; food intake; masticatory parameters and orofacial myofunctional characteristics. The children were divided according to nutritional status into normal weight (n = 101), overweight (n = 33) and obesity (n = 26) groups. Results: The results showed that Obese children had a larger bite size (g) (median = 6.0, Q1-Q3 = 4.0-9.0, p = 0.049) and performed fewer masticatory sequences (median = 3.0, Q1-Q3 = 2.0-3.2, p = 0.024) than children with normal weight (median = 5.0, Q1-Q3 = 4.0-7.0; median = 4.0, Q1-Q3 = 3.0-5.0). Furthermore, obese children finished feeding in a shorter time (s) (median = 62.5, Q1-Q3 = 50.5-70.0, p = 0.039) than normal weight children (median = 66.0, Q1-Q3 = 56.5-78.0) and overweight children (median = 66.0, Q1-Q3 = 58.0-81.5). Conclusions: The present results suggest that obese children present changes in mastication, evidenced by larger bite-size, performing fewer masticatory sequences and rapid mastication, which may contribute to increased food consumption and the development of excess weight.
RESUMO
Childhood obesity is a significant public health problem. Studies show that obese children are more likely to become obese adults. In an attempt to ascertain the factors associated with childhood obesity, research has shown that this condition is associated with changes in food consumption and masticatory performance. The aim of this study was thus to evaluate food consumption and masticatory performance in normal weight, overweight and obese children aged 7 - 12 years. A cross-sectional study was carried out with 92 children aged 7 - 12 years, of both sexes, from a public school in a Brazilian municipality. The children were divided into the following groups: normal weight (n = 48), overweight (n = 26) and obese (n = 18). Anthropometric parameters, food consumption, food consistency preference, and masticatory performance were evaluated. Pearson's chi-square test was used to compare categorical variables. To compare numerical variables, the one-way ANOVA test was applied. For variables not conforming to a normal distribution, the Kruskal-Wallis test was used. The level of statistical significance was set at p ≤ 0.05. Our results show that the children with obesity consumed fewer fresh foods (median = 3, IQI = 4.00-2.00, p = 0.026), consumed more ultra-processed foods (median = 4, IQI = 4.00-2.00, p = 0.011), performed fewer mastication sequences (median = 2, IQI = 3.00-2.00, p = 0.007), and ate faster (median = 58.50, IQI = 69.00-48.00, p = 0.026) compared to children of normal weight. We conclude that children with obesity exhibit differences in food consumption and masticatory performance compared to children of normal weight.
Assuntos
Sobrepeso , Obesidade Infantil , Masculino , Adulto , Feminino , Humanos , Criança , Estudos Transversais , Antropometria , Mastigação , Índice de Massa CorporalRESUMO
OBJECTIVE: The objective of this study was to analyze masticatory characteristics in children from 7 to 10 years, and to compare these characteristics among normal weight, overweight and obese children. METHODS: This is a cross-sectional study, conducted in northeast Brazil, with a sample of 160 children, aged 7 to 10 years. The authors evaluated: nutritional and dental status; food intake; masticatory parameters and orofacial myofunctional characteristics. The children were divided according to nutritional status into normal weight (n = 101), overweight (n = 33) and obesity (n = 26) groups. RESULTS: The results showed that Obese children had a larger bite size (g) (median = 6.0, Q1-Q3 = 4.0-9.0, p = 0.049) and performed fewer masticatory sequences (median = 3.0, Q1-Q3 = 2.0-3.2, p = 0.024) than children with normal weight (median = 5.0, Q1-Q3 = 4.0-7.0; median = 4.0, Q1-Q3 = 3.0-5.0). Furthermore, obese children finished feeding in a shorter time (s) (median = 62.5, Q1-Q3 = 50.5-70.0, p = 0.039) than normal weight children (median = 66.0, Q1-Q3 = 56.5-78.0) and overweight children (median = 66.0, Q1-Q3 = 58.0-81.5). CONCLUSIONS: The present results suggest that obese children present changes in mastication, evidenced by larger bite-size, performing fewer masticatory sequences and rapid mastication, which may contribute to increased food consumption and the development of excess weight.
Assuntos
Sobrepeso , Obesidade Infantil , Humanos , Criança , Mastigação , Estudos Transversais , Aumento de PesoRESUMO
Active play can contribute to the reduction of sedentary time and generate potential benefits for the performance of fundamental motor skills in children. Thus, the aim of this systematic review was to provide a synthesis of evidence on the contributions of active play to fundamental motor skills in children aged 2 to 5 years typically developed, as well as to verify the differences between the intervention protocols used in the studies. The studies were identified by searching the PubMed, Web of Science and Lilacs databases. Clinical trials available in English, conducted in typically developing children, were included, and studies with the theme of electronic games were excluded. Two independent researchers examined the studies and conducted data extraction. Eight articles were included in the systematic review; three identified that children who experienced interventions with free active play had better performance in handling and balance skills. Four studies identified that children who practiced guided active play had better performance in locomotion, manipulation and balance skills, one study found no significant difference. We concluded that the practice of active play, especially guided active play, positively contributes to the fundamental motor skills of children aged 3 to 5 years typically developed. (AU)
Brincadeiras ativas podem contribuir para redução do tempo sedentário e gerar potenciais benefícios para o desempenho das habilidades motoras fundamentais em crianças. Assim, o objetivo desta revisão sistemática foi fornecer uma síntese das evidências sobre as contribuições do brincar ativo para a habilidades motoras fundamentais em crianças de 2 a 5 anos tipicamente desenvolvidas, bem como verificar as diferenças entre os protocolos de intervenção utilizados nos estudos. Os estudos foram identificados por meio de busca nas bases de dados PubMed, Web of Science e Lilacs. Foram incluídos os ensaios clínicos disponíveis em inglês, realizados em crianças com desenvolvimento típico, e excluídos os estudos com a temática de jogos eletrônicos. Dois pesquisadores independentes examinaram os estudos e conduziram a extração de dados. Oito artigos foram incluídos na revisão sistemática; três identificaram que as crianças que vivenciaram intervenções com brincadeira ativa livre tiveram melhor desempenho nas habilidades de manuseio e equilíbrio. Quatro estudos identificaram que crianças que praticavam brincadeiras ativas orientadas tinham melhor desempenho nas habilidades de locomoção, manipulação e equilíbrio, um estudo não encontrou diferença significativa. Concluímos que a prática da brincadeira ativa, especialmente a orientada, contribui positivamente para o desempenho das habilidades motoras fundamentais de crianças de 3 a 5 anos tipicamente desenvolvidas. (AU)
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Jogos e Brinquedos , Escolas Maternais , Criança , Destreza Motora , PubMed , Crescimento e Desenvolvimento , Comportamento Sedentário , LILACS , Revisão Sistemática , LocomoçãoRESUMO
Maternal nutrition is an environmental determinant for offspring growth and development, especially in critical periods. Nutritional imbalances during these phases can promote dysregulations in food intake and feeding preference in offspring, affecting body composition. The aim of this review is to summarize and discuss the effects of maternal high-fat diet (HFD) on offspring feeding behavior and body composition. A search was performed in the PUBMED, SCOPUS, Web of Science, and LILACS databases. Inclusion criteria were studies in rodents whose mothers were submitted to HFD that assessed outcomes of food or caloric intake on offspring and food preference associated or not with body weight or body composition analysis. At the end of the search, 17 articles with the proposed characteristics were included. In these studies, 15 articles manipulated diet during pregnancy and lactation, 1 during pregnancy only, and 1 during lactation only. Maternal exposure to a HFD leads to increased food intake, increased preference for HFDs, and earlier food independence in offspring. The offspring from HFD mothers present low birthweight but become heavier into adulthood. In addition, these animals also exhibited greater fat deposition on white adipose tissue pads. In conclusion, maternal exposure to HFD may compromise parameters in feeding behavior and body composition of offspring, impairing the health from conception until adulthood.
Assuntos
Composição Corporal , Peso Corporal , Dieta Hiperlipídica/efeitos adversos , Comportamento Alimentar , Exposição Materna/efeitos adversos , Obesidade/patologia , Efeitos Tardios da Exposição Pré-Natal/patologia , Feminino , Humanos , Fenômenos Fisiológicos da Nutrição Materna , Obesidade/etiologia , Gravidez , Efeitos Tardios da Exposição Pré-Natal/etiologiaRESUMO
ABSTRACT Studies have shown that changes in mastication are related to overweight in children and adolescents as these changes influence the increase in food consumption. The objective of this article was to characterize, through a systematic review, the mastication in children and adolescents with overweight or obesity. For this, two independent authors performed a systematic review of the electronic databases: Medical Literature Analysis and Retrieval System Online, Scopus, Cumulative Index to Nursing and Allied Health, Web of Science and Latin American and Caribbean Literature in Health Sciences. Masticatory characteristics were considered as primary outcomes; the methods of analyzing mastication, the physical characteristics of the foods/materials used in the analyses and the fasting time were considered as secondary outcomes. This review was prepared in accordance with the items of the preferential reports for systematic analysis and meta-analysis. The systematic review protocol was submitted to the International Prospective Registry of Systematic Reviews. Nine articles were included in this review. The reviewed articles suggest that children and/or adolescents with overweight or obese present masticatory damages because they have worse masticatory performance and altered orofacial myofunctional characteristics.
RESUMO Estudos têm demonstrado que alterações na mastigação estão relacionadas ao excesso de peso em crianças e adolescentes, o que pode levar ao aumento do consumo alimentar. O objetivo deste artigo foi caracterizar, através de uma revisão sistemática, a mastigação em crianças e adolescentes com sobrepeso ou obesidade. Para isso, dois autores independentes realizaram uma revisão sistemática nas bases de dados eletrônicas Medical Literature Analysis and Retrieval System Online, Scopus, Cumulative Index to Nursing and Allied Health, Web of Science e Literatura Latino-Americana e do Caribe em Ciências da Saúde. As características mastigatórias foram consideradas desfechos primários; os métodos de análise da mastigação, as características físicas dos alimentos/materiais utilizados nas análises e o tempo de jejum foram classificados como desfechos secundários. Esta revisão foi elaborada de acordo com os itens dos relatórios preferenciais para análise sistemática e metanálises. O protocolo de revisão sistemática foi submetido ao Registro Internacional Prospectivo de Revisões Sistemáticas. Nove artigos foram incluídos nesta revisão. Os resultados dos artigos revisados sugerem que crianças e/ou adolescentes com sobrepeso ou obesidade apresentam danos mastigatórios, pois possuem pior performance mastigatória e características miofuncionais orofaciais alteradas.
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Adulto , Sistema Estomatognático/fisiologia , Criança , Adolescente , Sobrepeso , Mastigação/fisiologia , ObesidadeRESUMO
AIM: The aim of this study was to evaluate the effects of maternal exposure to a high-fat diet associated with neonatal administration of kaempferol on somatic growth, biochemical profile and feeding behavior in offspring. MATERIALS AND METHODS: Wistar rats were distributed according to diet during pregnancy and lactation into Control (C; 3.4 kcal/g; 12% kcal/lipids) or High-fat (HFD; 4.6 kcal/g; 51% kcal/lipids) groups. In the offspring, vehicle (V) or kaempferol (K, 1 mg/kg) were administered from the 8th until the 21st postnatal day (PND). Maternal body weight (BW), caloric intake and adiposity were measured. In the offspring, somatic growth parameters were evaluated on the 7th, 14th, 21st, 25th and 30th PND, except for BW, which was measured from the 8th to the 21st and from the 25th to the 30th PND. Feeding behavior was assessed by food intake and behavioral satiety sequence (BSS) on the 30th PND. The biochemical profile and relative weight of adipose tissue of offspring were also measured. KEY FINDINGS: Dams exposed to HFD showed no difference in body weight and caloric intake but exhibited increased adiposity. Neonatal administration of kaempferol increased body weight after weaning and somatic growth in the offspring of HFD dams. Neonatal kaempferol also reduced adiposity and serum creatinine levels in offspring. Neither maternal diet nor kaempferol altered offspring feeding behavior. SIGNIFICANCE: Neonatal administration of kaempferol promotes increased somatic growth post-weaning, reduces adiposity, and does not alter feeding behavior in offspring from high-fat dams.
Assuntos
Adiposidade/efeitos dos fármacos , Comportamento Alimentar/efeitos dos fármacos , Quempferóis/farmacologia , Tecido Adiposo , Animais , Animais Recém-Nascidos/metabolismo , Peso Corporal/efeitos dos fármacos , Dieta Hiperlipídica , Ingestão de Energia/efeitos dos fármacos , Feminino , Quempferóis/metabolismo , Lactação/efeitos dos fármacos , Masculino , Exposição Materna/efeitos adversos , Fenômenos Fisiológicos da Nutrição Materna , Obesidade/tratamento farmacológico , Gravidez , Ratos , Ratos Wistar , DesmameRESUMO
The neurotransmitter serotonin (5-HT) acts as an important regulator of the critical neurodevelopmental processes and thus alterations in 5-HT signaling early promotes permanent structural and functional changes in brain. The selective serotonin reuptake inhibitors (SSRIs), as fluoxetine and citalopram, blocking serotonin transporter (SERT) at the presynaptic neuron, which regulates extracellular 5-HT levels. Evidence suggests that the exposure to SSRIs in the neurodevelopmental period may alters 5-HT signaling sensitivity on food intake control. The aim of the present study was to evaluate the effects of neonatal exposure to fluoxetine on molecular and cellular components of the serotonergic system and food intake control in young animals. Methods: The animals were divided according to experimental manipulation, Fluoxetine Group (FG): male pups received application of fluoxetine (10â¯mg/kg, 10⯵L/g) and Saline Group (SG): male pups received saline application (0.9% NaCl, 10⯵L/g), both throughout lactation (PND1-PND21). They evaluated body weight, food intake, SERT gene and protein expression, serotonin content in the hypothalamus. The neonatal exposure to fluoxetine promoted reduction in body weight, disturb the serotonin hypophagic response, and increase the serotonin and SERT hypothalamic in young animals. We conclude that the changes of components of the serotonergic system by neonatal exposure to fluoxetine may be responsible for disturb the inhibitory action of serotonin on food intake.