RESUMO
BACKGROUND: The endoscopic retrograde cholangiopancreatography and magnetic resonance cholangiopancreatography were methods used for diagnosis of the diseases in the biliary and pancreatic ducts. AIM: Compare the diagnostic concordance among, analyzing sensitivity, specificity, positive predictive value, negative predictive value and accuracy. PATIENTS/METHODS: There were 41 patients in the studied group, divided in two groups: I--without biliary or pancreatic tract obstruction, and II--with obstruction. Group II was further divided in A--obstruction due to lithiasis, and B--due to other causes. RESULTS: Concordance between the two methods was found in 67% in group I and 82% in group II. Sensitivity of endoscopic retrograde cholangiopancreatography was 94% and magnetic resonance cholangiopancreatography was 89%. Specificity of endoscopic retrograde cholangiopancreatography was 100% and magnetic resonance cholangiopancreatography was 67%. Magnetic resonance cholangiopancreatography positive predictive value was 93%, the negative predictive value was 50% and the accuracy was 85%. CONCLUSION: Both methods showed the same sensitivity.
Assuntos
Colangiografia/métodos , Colestase/diagnóstico , Imageamento por Ressonância Magnética/métodos , Pancreatopatias/diagnóstico , Ductos Pancreáticos/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Colangiopancreatografia Retrógrada Endoscópica/métodos , Constrição Patológica/diagnóstico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ductos Pancreáticos/patologia , Valor Preditivo dos Testes , Sensibilidade e EspecificidadeRESUMO
This prospective multicentric randomized open trial was designed to evaluate the efficacy of ranitidine 150 mg bid vs 300 mg nocte in the short-term (4 weeks) treatment of duodenal ulcer in 15 Brazilian centers. On the basis of a randomization table 190 patients with endoscopically confirmed duodenal ulcer were allocated to receive either ranitidine 150 mg bid (94 pts) or 300 mg nocte (96 pts). The 2 treatment groups were well matched for age, sex, duration of ulcer disease, number and size of ulcers, duration of current episode, intensity of ulcer pain, alcohol and coffee intake and smoking habits. They were endoscopically controlled at the end of the 4 weeks. At 4 weeks 78 of 94 patients (83.0%) had their ulcers healed with the 150 mg bid regimen as opposed to 79 of 96 patients (82.3%) allocated to the 300 mg nocte dosage. This difference was not statistically significant. Ulcer symptoms diminished with treatment in both groups. The tolerability and compliance was excellent in both groups. The results show that ranitidine 300 mg nocte is as effective in the short-term treatment of duodenal ulcer as ranitidine 150 mg bid. Considering the greater simplicity of administration enhancing patient compliance, the treatment with 300 mg nocte is preferable.
Assuntos
Úlcera Duodenal/tratamento farmacológico , Ranitidina/administração & dosagem , Adolescente , Adulto , Brasil , Esquema de Medicação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ranitidina/efeitos adversos , Ranitidina/uso terapêuticoAssuntos
Adolescente , Adulto , Pessoa de Meia-Idade , Humanos , Masculino , Feminino , Cimetidina , Úlcera DuodenalRESUMO
Os autores apresentam dois casos de leiomioma de esofago. O principal sintoma foi disfagia. O diagnostico foi realizado pela radiologia e endoscopia. Tratados pela enucleacao extramucosa, nao apresentaram complicacoes pos-operatorias,com regressao total dos sintomas. Sao discutidos os aspectos clinicos, diagnosticos e terapeuticos, relacionando-os a uma revisao da literatura