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J Med Case Rep ; 18(1): 223, 2024 Apr 25.
Artigo em Inglês | MEDLINE | ID: mdl-38659067

RESUMO

BACKGROUND: Optic neuritis (ON) is an inflammatory demyelinating condition of the optic nerve, with various causes. Its incidence is higher in children and young adults than in older adults of both genders, but is more common in women than in men. ON is rarely associated with mydriasis, and it is seldom triggered by vaccines against tetanus and diphtheria. CASE REPORT: A 36-year-old Caucasian woman presented with bilateral ON that had started 18 days after administration of a booster dose of the double adult vaccine (dT) against diphtheria and tetanus. Bilateral mydriasis persisted after treatment and clinical resolution of the ON. She experienced severe headache, blurred vision, decreased visual acuity in the right eye and bilateral mydriasis, a diagnosis confirmed by imaging tests. Treatment with oral corticosteroids resulted in rapid resolution of the neuritis; however, mydriasis persisted for several months. CONCLUSION: This study describes a very unusual case of bilateral ON associated with prolonged mydriasis after vaccination against tetanus and diphtheria that regressed after treatment with oral corticosteroids. Prolonged mydriasis was the manifestation that differed from the other cases previously described.


Assuntos
Midríase , Neurite Óptica , Humanos , Neurite Óptica/induzido quimicamente , Neurite Óptica/etiologia , Feminino , Adulto , Midríase/induzido quimicamente , Midríase/etiologia , Vacinação/efeitos adversos , Resultado do Tratamento , Vacina contra Difteria e Tétano/efeitos adversos
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