RESUMO
Heart transplantation is an infrequent treatment modality in advanced congenital cardiopathy. We present the case of a 17-years old youngster coursing with a dilated Fallot's tetralogy, in terminal stage, who was subjected to an orthotopic heart transplantation. We present the most relevant data on his management during the 53 months after the surgery and discuss the long-term perspectives, which are comparable to those expected in transplanted patients due to other cardiac disorders.
Assuntos
Transplante de Coração , Tetralogia de Fallot/cirurgia , Adolescente , Progressão da Doença , Transplante de Coração/métodos , Humanos , MasculinoRESUMO
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is a common form of cancer which is found throughout the world. In recent years, the rates of HCC seem to have increased in European and North American countries. Herein, a retrospective review of necroscopy records over a 25-year period was undertaken in order to determine the incidence of HCC in a Mexican population. METHODOLOGY: A retrospective review of necroscopy records was performed to determine the incidence of HCC and then to determine the presence or absence of associated cirrhosis in these cases. The tumor/cirrhosis relationship was determined by computing the TC/T and TC/C indexes. RESULTS: Of 12556 autopsies studied, 73 cases of histologically proven HCC were reported, representing a total necropsy carcinoma incidence of 0.59%. Fifty-five cases were associated with cirrhosis (0.43%), and 18 were not (0.14%). HCC was two times more common in males (67%) than in females (33%), with a ratio of 2:1. During this period, the necropsy incidence of HCC rose steadily to twice its original level (1965-69 incidence 0.35%; 1985-89 incidence 0.69%). The necropsy incidence of cirrhosis was 4% (329 males, 185 females). The overall TC/T index was 75% (87% for males and 50% for females). The overall TC/C index was 10.7% (13% for males and 6.4% for females). CONCLUSIONS: There was a two-fold increase in the incidence of HCC in the Mexican population studied over a 25-year period. HCC was associated with cirrhosis in the majority of cases. HCC was two times more common in males than in females in patients with cirrhosis; in patients without cirrhosis, the ratio was 1:1. The incidence of cirrhosis was 4%, which remained unchanged with the passage of time.
Assuntos
Carcinoma Hepatocelular/epidemiologia , Cirrose Hepática/epidemiologia , Neoplasias Hepáticas/epidemiologia , Idoso , Autopsia/estatística & dados numéricos , Feminino , Humanos , Incidência , Masculino , México/epidemiologia , Estudos Retrospectivos , Fatores de TempoRESUMO
The Intracardiac ectopic thyroid is an extremely rare condition and there is no previous report on this subject in Mexico. This is the case of a 33 years old woman, with normal thyroid function. She was found to have an intracardiac tumor in the interventricular septum. The intraoperative biopsy showed typical thyroid follicules; tumor removal left a septal defect that was closed with a dacron patch suture. Two years follow-up showed normal echocardiographic images, good clinical status an normal thyroid functioning. A brief review of the literature is included.
Assuntos
Coristoma/patologia , Cardiopatias/patologia , Glândula Tireoide , Adulto , Coristoma/cirurgia , Feminino , Cardiopatias/cirurgia , HumanosRESUMO
Hepatoblastoma is the most frequent primary malignant liver neoplasm in childhood; in adults it is extremely rare and only 27 cases have been published. The prognosis of this neoplasm is poor because it is usually discovered late. Surgery, chemotherapy and liver transplantation have been tried with poor results. We present two adult patients who were diagnosed with an epithelial hepatoblastoma. The pathogenesis, histologic features and current management is reviewed.
Assuntos
Hepatoblastoma/diagnóstico , Neoplasias Hepáticas/diagnóstico , Adulto , Biópsia , Emergências , Evolução Fatal , Feminino , Hepatoblastoma/patologia , Hepatoblastoma/cirurgia , Humanos , Laparotomia , Fígado/patologia , Neoplasias Hepáticas/patologia , Neoplasias Hepáticas/cirurgia , PrognósticoRESUMO
El presente caso reviste interes debido a que es un ejemplo representativo de lo que los procedimientos no invasivos de imagen pueden ayudar al diagnostico de padecimientos neoplasicos. En particular la ultrasonografia, que es considerada por algunos, como poco util en la valoracion de la glandula suprarenal. En nuestro paciente mostro imagenes caracteristicas aun mas demostrativas que con la misma tomografia computada, debido probablemente a su gran tamano. El estudio fue completado con arteriografia. El estudio anatomopatologico comprobo la impresion diagnostica inicial
Assuntos
Adulto , Humanos , Masculino , Angiografia , Tomografia Computadorizada por Raios X , Ultrassonografia , Neoplasias das Glândulas SuprarrenaisAssuntos
Aorta Abdominal/cirurgia , Prótese Vascular , Artérias Carótidas/transplante , Animais , Aneurisma Aórtico/etiologia , Prótese Vascular/efeitos adversos , Artérias Carótidas/efeitos dos fármacos , Bovinos , Feminino , Ficina/farmacologia , Masculino , Preservação de Órgãos , Pepsina A/farmacologia , Ratos , Ratos Endogâmicos , Amido/análogos & derivados , Amido/farmacologia , Transplante HeterólogoRESUMO
A case of Krabbe's leukodystrophy is reported in a male child 18 months old, with evolution of 12 months. The clinical, radiological, pathological and genetic studies are described. Besides, this case was the basis to review the topic of leukodystrophy and the corresponding literature, considering that this is an uncommon disease in our milieu.