RESUMO
This paper presents a two-stage motion compensation coding scheme for image sequences in hemodynamics. The first stage of the proposed method implements motion compensation, and the second stage corrects local pixel intensity distortions with a context adaptive linear predictor. The proposed method is robust to the local intensity distortions and the noise that often degrades these image sequences, providing lossless and near-lossless quality. Our experiments with lossless compression of 12bits/pixel studies indicate that, potentially, our approach can perform 3.8%, 2% and 1.6% better than JPEG-2000, JPEG-LS and the method proposed by Scharcanski [1], respectively. The performance tends to improve for near-lossless compression. Therefore, this work presents experimental evidence that for coding image sequences in hemodynamics, an adequate motion compensation scheme can be more efficient than the still-image coding methods often used nowadays.
Assuntos
Algoritmos , Angiografia/métodos , Artefatos , Compressão de Dados/métodos , Intensificação de Imagem Radiográfica/métodos , Humanos , Movimento (Física) , Reprodutibilidade dos Testes , Sensibilidade e EspecificidadeRESUMO
This paper presents a context adaptive coding method for image sequences in hemodynamics. The proposed method implements motion compensation through of a two-stage context adaptive linear predictor. It is robust to the local intensity changes and the noise that often degrades these image sequences, and provides lossless and near-lossless quality. Our preliminary experiments with lossless compression of 12 bits/pixel studies indicate that, potentially, our approach can perform 3.8%, 2% and 1.6% better than JPEG-2000, JPEG-LS and the method proposed in [1], respectively. The performance tends to improve for near-lossless compression.
Assuntos
Algoritmos , Angiografia/métodos , Compressão de Dados/métodos , Aumento da Imagem/métodos , Interpretação de Imagem Assistida por Computador/métodos , Processamento de Sinais Assistido por Computador , Gravação em Vídeo/métodos , Humanos , Reprodutibilidade dos Testes , Sensibilidade e EspecificidadeRESUMO
BACKGROUND: The most common complication experienced by patients who have undergone mammary implant surgery is capsular contracture. This matter concerns physicians and patients, but to date, there is no effective way to avoid this complication. Surgical intervention usually is required. In 2002, the use of zafirlukast, a leukotriene inhibitor (a drug used for asthma treatment), was reported for the treatment of capsular contracture, with good results. METHODS: For this study, 30 female Wistar rats were used. These animals received two silicone implants each: one with a smooth surface and one with a textured surface. All the animals received daily intraperitoneal injections for 90 days and were divided as follows: control group (C) receiving only saline solution, experimental group 1 (E-I) receiving 1.25 mg/kg/day of zafirlukast, and experimental group 2 (E-II) receiving 5 mg/kg/day of zafirlukast. Histologic analysis used hematoxilin and eosin to verify vessels, capsule thickness, and inflammatory cells. Immunoistochemical analysis with smooth muscle anti-actin antibody was used for myofibroblast verification. Picro-Sirius under polarized light was used for collagen analysis. RESULTS: Textured implant experimental groups presented smaller numbers of vessels, thinner capsules, lower collagen density, and smaller numbers of mastocytes and eosinophils than the control group. No significant differences were found in smooth surface implants, as compared with the control group. CONCLUSION: Zafirlukast reduced the occurrence of factors directly and indirectly connected with capsular contracture.